Elaidic Acid-d17

Elaidic Acid-d17 is intended for use as an internal standard for the quantification of elaidic acid (Cay-90250) by GC- or LC-MS. Elaidic acid is a monounsaturated trans fatty acid and the 9-trans isomer of oleic acid (Cay-90260, Cay-24659) that has been found in partially hydrogenated cooking oils. It reduces HHT and HETE formation and increases synthesis of prostaglandin E2 (PGE2, Cay-14010), PGF2alpha (Cay-16010, Cay-16020), PGD2 (Cay-12010), and thromboxane B2 (TXB2, Cay-19030) induced by arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) in isolated human platelets. Elaidic acid (0.1-5 mmol/L) induces apoptosis in human umbilical vein endothelial cells (HUVECs). In vivo, elaidic acid (100 mg/kg) reduces cardiac and hepatic autophagy induced by palmitic acid (Cay-10006627) in mice.Formal Name: (E)-octadec-9-enoic-11,11,12,12,13,13,14,14,15,15,16,16,17,17,18,18,18-d17 acid. Synonyms: C18:1(9E)-d17, 9(E)-Oleic Acid-d17, FA 18:1-d17, trans-Oleic Acid-d17. Molecular Formula: C18H17D17O2. Formula Weight: 299.6. Purity: >99% deuterated forms (d1-d17). Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml. SMILES: [2H]C(/C=C/CCCCCCCC(O)=O)([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]. InChi Code: InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9+/i1D3,2D2,3D2,4D2,5D2,6D2,7D2,8D2. InChi Key: ZQPPMHVWECSIRJ-GSLIECEWSA-N. Side Chain Carbon Sum: 18:1.