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Eicosapentaenoic acid-d10 (EPA-d10) is an oxidation-resistant form of EPA that is deuterated at its bis-allylic sites, which are the targets of lipid peroxidation. The substitution of deuterium for hydrogen atoms in fatty acids at bis-allylic sites can reduce lipid peroxidation at those sites by decreasing the rate of hydrogen abstraction, an effect known as the kinetic isotope effect. Formal Name: (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic-7,7,10,10,13,13,16,16,19,19-d10 acid. Synonyms: C20:5(5Z,8Z,11Z,14Z,17Z)-d10 C20:5-d10 n-3 EPA-d10 FA 20:5-d10 Timnodonic Acid-d10. Molecular Formula: C20H20D10O2. Formula Weight: 312.5. Purity: >95%. Formulation (Request formulation change): A 5 mg/ml solution in ethanol. Solubility: Ethanol: Sparingly soluble: 1-10 mg/ml. SMILES: OC(CCC/C=C\C([2H])([2H])/C=C\C([2H])([2H])/C=C\C([2H])([2H])/C=C\C([2H])([2H])/C=C\C([2H])([2H])C)=O. InChi Code: InChI=1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15-/i2D2,5D2,8D2,11D2,14D2. InChi Key: JAZBEHYOTPTENJ-REVZQTCTSA-N. Storage: -20°C. Stability: > 2 years.
Keywords:
C20:5(5Z,8Z,11Z,14Z,17Z)-d10, C20:5-d10 n-3, EPA-d10, FA 20:5-d10, Timnodonic Acid-d10, (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic-7,7,10,10,13,13,16,16,19,19-d10 acid
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