DSPE-Polysarcosine66

DSPE-polysarcosine66 is an amine-functionalized hydrophilic polymer. It is a polysarcosine-labeled form of 1,2-distearoyl-rac-glycero-3-phosphoethanolamine (DSPE). Polysarcosines have been used as alternatives to PEGylation in lipid nanoparticles (LNPs) and to reduce the immunogenicity of administered proteins in vivo.Formal Name: (2R)-3-((hydroxy(2-(2-(methyl((methylamino)methyl)amino)acetamido)ethoxy)phosphoryl)oxy)propane-1,2-diyl distearate. Synonyms: 1,2-Dioctadecanoyl-rac-glycero-3-Phosphoethanolamine-Polysarcosine66, 1,2-Distearoyl-rac-glycero-3-PE Polysarcosine66, 1,2-Distearoyl-rac-glycero-3-Phosphatidylethanolamine-Polysarcosine66, 1,2-Distearoyl-rac-glycero-3-Phosphoethanolamine-Polysarcosine66, 1,2-DPSE-Polysarcosine66, DSPE-pSar66, 18:0/18:0-PE-Polysarcosine66, PE(18:0/18:0)-Polysarcosine66. Molecular Formula: (C3H5NO)nC43H87N2O8P. Formula Weight: 862.2. Purity: >95%. Formulation: (Request formulation change), A solution in methanol. Solubility: Chloroform: Soluble. SMILES: CCCCCCCCCCCCCCCCCC(OC[C@@](COP(O)(OCCNC(CN(C)CNC)=O)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)=O. InChi Code: InChI=1S/C46H92N3O9P/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-45(51)55-40-43(41-57-59(53,54)56-38-37-48-44(50)39-49(4)42-47-3)58-46(52)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h43,47H,5-42H2,1-4H3,(H,48,50)(H,53,54)/t43-/m1/s1. InChi Key: IEQBKEBGSVOKGN-VZUYHUTRSA-N.