DSPE-PEG(2000)-TCO

DSPE-PEG(2000)-TCO is a PEGylated derivative of 1,2-distearoyl-sn-3-phosphoethanolamine (1,2-DSPE) that contains a trans-cyclooctene (TCO) moiety, which reacts with tetrazine rings and can be used for bioorthogonal ligation of lipid nanoparticles (LNPs). Formal Name: (2R)-3-((((1-(((S,E)-cyclooct-4-en-1-yl)oxy)-1,9-dioxo-5,8-dioxa-2,10-diazadodecan-12-yl)oxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl distearate. Synonyms: 1,2-Distearoyl-sn-glycero-3-PE-Polyethylene Glycol-2000-trans-cyclooctene 1,2-Distearoyl-sn-glycero-3-Phosphoethanolamine-Polyethylene Glycol-2000-trans-cyclooctene. Molecular Formula: (C2H4O)nC53H99N2O12P. Purity: >95%. Formulation (Request formulation change): A solid. Solubility: DMSO: Slightly soluble: 0.1-1 mg/ml Ethanol: Sparingly soluble: 1-10 mg/ml. SMILES: O=C(NCCOP(O)(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O)=O)OCCOCCNC(O[C@H]1CCC/C=C/CC1)=O. Storage: -20°C. Stability: > 4 years.