Docosanoic Acid

Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils. It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM). Docosanoic acid inhibits rat DNA polymerase beta and human DNA polymerase lambda activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM. Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet. Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.CAS Number: 112-85-6. Synonyms: Behenic Acid, C22:0, DCA, FA 22:0, NSC 32364. Molecular Formula: C22H44O2. Formula Weight: 340.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 3 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml. SMILES: CCCCCCCCCCCCCCCCCCCCCC(=O)O. InChi Code: InChI=1S/C22H44O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h2-21H2,1H3,(H,23,24). InChi Key: UKMSUNONTOPOIO-UHFFFAOYSA-N. Side Chain Carbon Sum: 22:0.