Docosahexaenoyl Serinol

Docosahexaenoyl serinol is a derivative of 2-docosahexaenoyl glycerol (2-DG). It inhibits the growth of A549 human lung adenocarcinoma cells (IC50 = 0.48 µM). It also inhibits degranulation of RBL-2H3 mast cells (IC50 = 16 µM). Oral administration of docosahexaenoyl serinol (20 mg/animal) suppresses the IgE-dependent passive cutaneous anaphylaxis (PCA) reaction by 17% in mice.Formal Name: N-(1,3-dihydroxypropan-2-yl)docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenamide. CAS Number: 1638355-62-0. Synonyms: Docosahexaenoyl Serinolamide. Molecular Formula: C25H39NO3. Formula Weight: 401.6. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Chloroform: soluble. SMILES: CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(NC(CO)CO)=O. InChi Code: InChI=1S/C25H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(29)26-24(22-27)23-28/h3-4,6-7,9-10,12-13,15-16,18-19,24,27-28H,2,5,8,11,14,17,20-23H2,1H3,(H,26,29)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-. InChi Key: WLQISWHMHISXMV-KUBAVDMBSA-N.