Cholesteryl Myristate

Cholesteryl myristate is a cholesterol ester. Levels of cholesteryl myristate are increased in the serum, liver, and aorta in rabbits fed a high-cholesterol diet and positively correlate with development of non-alcoholic fatty liver disease (NAFLD). Plasma levels of cholesteryl myristate also positively correlate with the presence of unstable atherosclerotic plaques in coronary artery disease. Cholesterol myristate has been used in the composition of lipid nanoparticles (LNPs) as a drug carrier systems for drugs with low water solubility.Formal Name: (3beta)-cholest-5-en-3-ol 3-tetradecanoate. CAS Number: 1989-52-2. Synonyms: Cholesterol Myristate, Cholesteryl Tetradecanoate, Myristic Acid cholesteryl ester, NSC 226867. Molecular Formula: C41H72O2. Formula Weight: 597.0. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: Chloroform: 10 mg/mL. SMILES: C[C@]12C(C[C@@H](OC(CCCCCCCCCCCCC)=O)CC2)=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4([C@@H](CCCC(C)C)C)[H]. InChi Code: InChI=1S/C41H72O2/c1-7-8-9-10-11-12-13-14-15-16-17-21-39(42)43-34-26-28-40(5)33(30-34)22-23-35-37-25-24-36(32(4)20-18-19-31(2)3)41(37,6)29-27-38(35)40/h22,31-32,34-38H,7-21,23-30H2,1-6H3/t32-,34+,35+,36-,37+,38+,40+,41-/m1/s1. InChi Key: SJDMTGSQPOFVLR-ZPQCIJQQSA-N. Side Chain Carbon Sum: 14:0.