Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10006400-1 1 mg -

6 - 10 business days*

Cay10006400-5 5 mg -

6 - 10 business days*

Cay10006400-10 10 mg -

6 - 10 business days*

Cay10006400-50 50 mg -

6 - 10 business days*

20-HETE is an important metabolite of arachidonic acid in the vasculature, especially in the... more
Product information "CAY10462"
20-HETE is an important metabolite of arachidonic acid in the vasculature, especially in the kidney, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. Alkylaryl imidazoles have been shown to inhibit certain CYP450 enzymes, including the CYP4A enzymes associated with 20-HETE synthesis. CAY10462 is the hydrochloride salt of CAY10434 and selective inhibitor of the 20-HETE synthase CYP4A11 exhibiting an IC50 of 8.8 nM when tested in human renal microsomes. CAY10434 is nearly 200 times less potent as an inhibitor of 1A, 1C, and 3A CYP450 enzymes. Formal Name: 6-[4-(1H-imidazol-1-yl)phenoxy]-N,N-dimethyl-1-hexanamine, dihydrochloride. CAS Number: 502656-68-0. Molecular Formula: C17H25N3O . 2HCl. Formula Weight: 360.3. Purity: >98%. Formulation: A crystalline solid. Solubility: DMSO: 15 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 202, 246 nm. SMILES: CN(C)CCCCCCOC1=CC=C(N2C=CN=C2)C=C1.Cl.Cl. InChi Code: InChI=1S/C17H25N3O.2ClH/c1-19(2)12-5-3-4-6-14-21-17-9-7-16(8-10-17)20-13-11-18-15-20,,/h7-11,13,15H,3-6,12,14H2,1-2H3,2*1H. InChi Key: SRCWAJONAASSNJ-UHFFFAOYSA-N.
Keywords: 6-[4-(1H-imidazol-1-yl)phenoxy]-N,N-dimethyl-1-hexanamine, dihydrochloride
Supplier: Cayman Chemical
Supplier-Nr: 10006400


Application: CYP4A11 inhibitor
MW: 360.3 D
Formula: C17H25N3O . 2HCl
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 502656-68-0| Matching products

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