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A family of related G-protein coupled receptors that bind sphingosine-1 phosphate (S1P) as a high-affinity ligand have recently been cloned. S1P3/EDG3 is a member of this family that is widely expressed in many tissues, signaling via the ERK-½ and PLC/IP3 pathways. CAY10444 is a selective antagonist of S1P binding to the S1P3 receptor, blocking the calcium increase in HeLa cells by about 40% when present at 10 µM. Formal Name: 2-undecyl-thiazolidine-4-carboxylic acid. CAS Number: 298186-80-8. Synonyms: BML-241. Molecular Formula: C15H29NO2S. Formula Weight: 287.5. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: .5 mg/ml, DMF:PBS (pH 7.2)(1:3): .15 mg/ml. SMILES: [H]N1C(CCCCCCCCCCC)SC[C@H]1C(O)=O. InChi Code: InChI=1S/C15H29NO2S/c1-2-3-4-5-6-7-8-9-10-11-14-16-13(12-19-14)15(17)18/h13-14,16H,2-12H2,1H3,(H,17,18). InChi Key: FNBSOIBCKUUVJJ-UHFFFAOYSA-N.