C8 Ceramide-mPEG(2000)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
Cay41954-1	1 mg		-	-	6 - 10 business days*		399.00€
Cay41954-5	5 mg		-	-	6 - 10 business days*		798.00€

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A PEGylated form of C8 ceramide, has been used in the generation of lipoplexes and lipid... more

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Product information "C8 Ceramide-mPEG(2000)"

A PEGylated form of C8 ceramide, has been used in the generation of lipoplexes and lipid particles for the delivery of plasmid DNA and siRNA in vitro and in vivo, lipid particles encapsulating plasmid DNA and containing C8 MPEG(2000) ceramide have a higher transfection efficiency than those containing C14- or C20 MPEG(2000) ceramide in BHK cells, lipoplexes containing C8 MPEG(2000) ceramide and encapsulating siRNAs targeting HPV E7 peptide and Mcl-1 induce apoptosis in Ca Ski and SiHa cervical cancer cells, intravaginal administration of lipoplexes containing C8 MPEG(2000) ceramide accumulate in vaginal tissue in mice. Formulation: A solid. InChI: . InChIKey: . SMILES: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC(CCCCCCC)=O)COC(CCC(OCCOC)=O)=O

Keywords:	Capryl Ceramide Methoxy Polyethylene Glycol-2000, N-Capryl-D-erythro-Sphingosine mPEG(2000), N-Octanoyl-D-erythro-Sphingosine mPEG(2000), a-[4-[[(2S,3R,4E)-3-hydroxy-2-[(1-oxooctyl)amino]-4-octadecen-1-yl]oxy]-1,4-dioxobutyl]-methoxy-poly(oxy-1,2-ethanedi
Supplier:	Cayman Chemical
Supplier-Nr:	41954