C20 Sphingomyelin (d18:1/20:0)

C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin (Cay-13104) and in human plasma where it is positively correlated with insulin resistance in obese humans. C20 sphingomyelin is also upregulated in the liver of a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder. The plasma concentration of C20 sphingomyelin is decreased in men with prostate cancer. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1917]Formal Name: 4-hydroxy-7S-[(1R,2E)-1-hydroxy-2-hexadecen-1-yl]-N,N,N-trimethyl-9-oxo-3,5-dioxa-8-aza-4-phosphaoctacosan-1-aminium, 4-oxide, inner salt. CAS Number: 121999-68-6. Synonyms: N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine, SM(d18:1/20:0). Molecular Formula: C43H87N2O6P. Formula Weight: 759.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform:Methanol (14:1): soluble, Ethanol: soluble, Methanol: soluble. SMILES: O=C(CCCCCCCCCCCCCCCCCCC)N[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)[C@H](O)/C=C/CCCCCCCCCCCCC. InChi Code: InChI=1S/C43H87N2O6P/c1-6-8-10-12-14-16-18-20-21-22-23-25-27-29-31-33-35-37-43(47)44-41(40-51-52(48,49)50-39-38-45(3,4)5)42(46)36-34-32-30-28-26-24-19-17-15-13-11-9-7-2/h34,36,41-42,46H,6-33,35,37-40H2,1-5H3,(H-,44,47,48,49)/b36-34+/t41-,42+/m0/s1. InChi Key: AADLTHQNYQJHQV-SVLGDMRNSA-N.