Butenoyl PAF

Butenoyl PAF
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay60929-1 1 mg -

3 - 10 business days*

80.00€
Cay60929-5 5 mg -

3 - 10 business days*

360.00€
Cay60929-10 10 mg -

3 - 10 business days*

640.00€
Cay60929-50 50 mg -

3 - 10 business days*

2,800.00€
 
Butenoyl and butanoyl PAF are both products of the oxidative decomposition of 2-arachidonoyl... more
Product information "Butenoyl PAF"
Butenoyl and butanoyl PAF are both products of the oxidative decomposition of 2-arachidonoyl phospholipids. Oxygenation of C-5 of the 5,6 double bond followed by cleavage of the hydroperoxide results in a PAF-like compound with a 4-carbon residue esterified in the sn-2 position, similar oxidized lipid products also act as ligands for oxidized lipid receptors and peroxisome proliferator-activated receptor. Although butenoyl PAF is 10-fold less potent than PAF as a PAF receptor agonist, it is present in amounts 100-fold greater than enzymatically generated PAF. Therefore, oxidation of LDL phospholipids generates physiologically relevant bioactive PAF-like molecules. Formal Name: 1-O-hexadecyl-2-O-(2E-butenoyl)-sn-glyceryl-3-phosphocholine. CAS Number: 474944-25-7. Molecular Formula: C28H56NO7P. Formula Weight: 549.7. Purity: >98%. Formulation: A solution in ethanol. Solubility: DMF: 10 mg/ml, DMSO: .5 mg/ml, Ethanol: Miscible, PBS (pH 7.2): 5 mg/ml. SMILES: O=C(/C=C/C)O[C@@H](COP([O-])(OCC[N+](C)(C)C)=O)COCCCCCCCCCCCCCCCC. InChi Code: InChI=1S/C28H56NO7P/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-20-23-33-25-27(36-28(30)21-7-2)26-35-37(31,32)34-24-22-29(3,4)5/h7,21,27H,6,8-20,22-26H2,1-5H3/b21-7+/t27-/m1/s1. InChi Key: SRZBVCCSIMMDOV-UUUXUCBLSA-N. Side Chain Carbon Sum: 20:1.
Keywords: 1-O-hexadecyl-2-O-(2E-butenoyl)-sn-glyceryl-3-phosphocholine
Supplier: Cayman Chemical
Supplier-Nr: 60929

Properties

Application: Bioactive lipid assays
MW: 549.7 D
Formula: C28H56NO7P
Purity: >98%
Format: Solution

Database Information

CAS : 474944-25-7| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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