Arachidonoyl amide

Arachidonoyl amide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10007295-5 5 mg -

3 - 10 business days

42.00€
Cay10007295-10 10 mg -

3 - 10 business days

79.00€
Cay10007295-25 25 mg -

3 - 10 business days

187.00€
Cay10007295-50 50 mg -

3 - 10 business days

330.00€
 
Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and... more
Product information "Arachidonoyl amide"
Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase (FAAH). Arachidonoyl amide is an analog of anandamide (AEA) that lacks the hydroxyethyl moiety. It is hydrolyzed by FAAH more effectively than AEA but exhibits significantly weaker binding to the human CB1 receptor with a Ki of 9.6 µM. Arachidonoyl amide and AEA exhibit similar binding and translocation into cells via the AEA transporter. It inhibits [3H]-AEA uptake into human astrocytoma cells with an IC50 of 9 µM. Arachidonoyl amide also inhibits rat glial gap junction cell-cell communication by 90% at a concentration of 20 µM.
Keywords: Arachidonamide, Arachidonic Acid amide, 5Z,8Z,11Z,14Z-eicosatetraenamide
Supplier: Cayman Chemical
Supplier-Nr: 10007295-5

Properties

Application: Bioactive lipid assays
MW: 303.5 D
Formula: C20H33NO
Purity: >98%
Format: Solution

Database Information

CAS : 85146-53-8| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H336, EUH066
P Phrases: P210, P240, P241, P242, P243, P261, P264, P271, P280, P312, P303+P361+P353, P304+P340, P305+P351+P338, P337+P313, P370+P378, P405, P403+P233, P403+P235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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