Allolithocholic Acid

Allolithocholic acid is a secondary allomonohydroxy bile acid. It activates large-conductance calcium-activated potassium channels (BK/KCas, EC50 = 44.21 µM in Xenopus oocytes expressing the rat channel). Fecal levels of allolithocholic acid are increased in patients with colorectal cancer. Allolithocholic acid has also been found in the urine of infants with biliary atresia.Formal Name: (3alpha,5alpha)-3-hydroxy-cholan-24-oic acid. CAS Number: 2276-94-0. Synonyms: 3alpha-hydroxy-5alpha-Cholanoic Acid, allo-LCA. Molecular Formula: C24H40O3. Formula Weight: 376.6. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Slightly soluble, Ethanol: Slightly soluble, Methanol: Slightly soluble. SMILES: C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C. InChi Code: InChI=1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16+,17-,18+,19-,20+,21+,23+,24-/m1/s1. InChi Key: SMEROWZSTRWXGI-NWFSOSCSSA-N.