all-trans Retinal

all-trans Retinal is a natural retinoid that is derived from vitamin A. It is the oxidation product of all-trans retinol and associates with cellular retinol-binding protein-I (CRBP-I) and CRBP-II (Kds = 50 and 90 nM, respectively), which are involved in the intracellular transport of retinol. all-trans Retinal is also an intermediate of the phototransduction pathway of photoreceptors, including rhodopsin and bacterial opsins. As a chemically reactive aldehyde, all-trans retinal can form toxic conjugates with proteins and lipids, leading to degeneration of the retina.Formal Name: retinal. CAS Number: 116-31-4. Synonyms: Retinaldehyde, Vitamin A aldehyde. Molecular Formula: C20H28O. Formula Weight: 284.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/mL, DMSO: 16 mg/mL, Ethanol: 25 mg/mL, Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL. lambdamax: 248, 380 nm. SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C([H])=O)C(C)(C)CCC1. InChi Code: InChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+. InChi Key: NCYCYZXNIZJOKI-OVSJKPMPSA-N.