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SQ 29,548
Item number: Cay19025-1
SQ 29,548 is a highly selective TP receptor antagonist which binds to the human recombinant TP receptor with a Ki of 4.1 nM. It inhibits the aggregation of washed human platelets induced by U-46619 with an IC50 of 0.06 µM. It antagonizes U-46619 induced contraction of rat and guinea pig tracheal, arterial, and...
| Keywords: | [1S-[1alpha,2alpha(Z),3alpha,4alpha]]-7-[3-[[2-[(phenylamino)carbonyl]hydrazino]methyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-he... |
| Application: | TP receptor antagonist |
| CAS | 98672-91-4 |
| MW: | 387.5 D |
From 132.00€
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25-hydroxy Cholesterol
Item number: Cay11097-5
25-hydroxy Cholesterol is an oxysterol. It is formed from cholesterol by cholesterol-25-hydroxylase, and its production can be induced by inflammation or infection. 25-hydroxy Cholesterol suppresses endogenous cholesterol synthesis by binding to insulin-induced gene (INSIG) proteins and preventing sterol regulatory...
| Keywords: | 25-OH Cholesterol, cholest-5-ene-3beta,25-diol |
| Application: | Metabolic studies |
| CAS | 2140-46-7 |
| MW: | 402.7 D |
From 45.00€
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Prostaglandin D2-d4
Item number: Cay312010-25
Prostaglandin D2-d4 (PGD2-d4) is intended for use as an internal standard for the quantification of PGD2 by GC- or LC-mass spectrometry. PGD2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of...
| Keywords: | PGD2-d4, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid |
| Application: | Standard |
| CAS | 211105-29-2 |
| MW: | 356.5 D |
From 148.00€
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Palmitoyl Ethanolamide
Item number: Cay90350-5
Palmitoyl ethanolamide (PEA) is an endogenous fatty N-acyl ethanolamine and a derivative of the endocannabinoid arachidonoyl ethanolamide (AEA, Cay-90050). It selectively activates peroxisome proliferator-activated receptor alpha (PPARalpha, EC50 = 3.1 µM) over PPARbeta/delta and PPARgamma in HeLa cells expressing...
| Keywords: | Palmidrol, PEA, N-(2-hydroxyethyl)-hexadecanamide |
| Application: | Bioactive lipid assays |
| CAS | 544-31-0 |
| MW: | 299.5 D |
From 53.00€
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10(S),17(S)-DiHDHA
Item number: Cay10008128-25
Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities. 10(S),17(S)-DiHDHA is a DHA metabolite, also referred to as protectin DX (PDX). It is produced by an apparent double lipoxygenase...
| Keywords: | 10(S),17(S)-DiHDoHE, PDX, Protectin DX, 10(S),17(S)-dihydroxy-4Z,7Z,11E,13Z,15E,19Z-docosahexaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 871826-47-0 |
| MW: | 360.5 D |
From 280.00€
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Leukotriene E4
Item number: Cay20410-25
Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4, leaving only the cysteinyl group still attached to the fatty acid backbone. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities...
| Keywords: | LTE4, 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 75715-89-8 |
| MW: | 439.6 D |
From 229.00€
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AMG 1541
Item number: Cay44932-1
AMG 1541 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. LNPs containing AMG 1541 accumulate in the muscle or liver after intramuscular or intravenous administration, respectively, in mice. AMG 1541-containing LNPs encapsulating...
| Keywords: | (1,4,7,10,13,16-hexaazacyclooctadecane-1,4,7,10,13,16-hexayl)hexakis(2-hydroxypropane-3,1-diyl)... |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 3092408-38-0 |
| MW: | 1784.63 D |
From 110.00€
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Phosphatidylethanolamine (bovine liver)
Item number: Cay45091-1
Phosphatidylethanolamine is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids. In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It...
| Keywords: | PE (bovine liver) |
| Application: | Glycerophospholipid |
| CAS | 383907-31-1 |
From 69.00€
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol (sodium...
Item number: Cay45187-10
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol is a glycerophospholipid formed by phospholipase D in the presence of ethanol. It has commonly been used as a biomarker of alcohol consumption and can be detected in the blood for approximately one month.. SMILES:...
| Keywords: | 16:0-18:1 Phosphatidylethanol-IsoPure, 1-Hexadecanoyl-2-(9(Z)-octadecenoyl)-sn-glycero-3-phosphoethanol,... |
| Application: | Phospholipid, alcohol consumption biomarker |
| CAS | 322647-55-2 |
| MW: | 724.98 D |
From 68.00€
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Cholesteryl Hemisuccinate (tris salt)
Item number: Cay45505-100
Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity. It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 µM, respectively. Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize...
| Keywords: | Cholesterol Hemisuccinate, Cholesterol Hydrogen Succinate, Cholesterol Monosuccinate, Succinate Cholesterol Monoester,... |
| Application: | Cholesterol ester, anticancer agent, ionizable anionic detergent, emulsifying agent |
| CAS | 102601-49-0 |
| MW: | 607.87 D |
From 95.00€
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Turonicin A
Item number: Cay45511-1
Turonicin A is a polyketide synthase-derived linear polyene originally isolated from Streptomyces that has antifungal and antibacterial activities. It is active against C. albicans, S. cerevisiae, B. subtilis, and S. aureus (MICs = 2.7, 0.7, 85, and 340 nM, respectively).. SMILES:...
| Keywords: | (2E,4E,6E,8E,12E,14S,15S,16S,17R,18E,20E,22E,24E,26E,29S,30S,33R,35S,37S,38E,41R,43S,45R,47S,48E,51S,52E,55R)-58-guanidino... |
| Application: | Polyketide, antifungal / antibacterial agent |
| CAS | 3059457-35-8 |
| MW: | 1138.49 D |
From 355.00€
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Myristoyl Tetrapeptide-12 (acetate)
Item number: Cay45604-10
Myristoyl tetrapeptide-12 is a polymeric acylated biosurfactant. It has a critical micelle concentration of less than 200 ppm in aqueous minimal essential media (MEM) and is active against E. coli, C. albicans, P. aeruginosa, and S. aureus (MICs = =100 ppm). Formulations containing myristoyl tetrapeptide-12 have...
| Keywords: | Myr-Lys-Ala-Lys-Ala-NH2, N2-(1-oxotetradecyl)-L-lysyl-L-alanyl-L-lysyl-L-alaninamide, acetate |
| Application: | Polymeric acylated biosurfactant |
| MW: | 625.9 D |
From 42.00€
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