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NEW
Bofanglutide (trifluoroacetate salt)
Item number: Cay44596-1
A GLP-1 derivative, binds to GLP-1R in HEK293 cells expressing the human receptor (IC50 = 3.67 nM), enhances glucose-stimulated insulin secretion in isolated mouse pancreatic beta-cells at 30 and 90 nM, decreases non-fasting blood glucose levels in db/db mice (ED50 = 3.024 nmol/kg), reduces food and water intake and...
| Keywords: | GZR18, 7-37-glucagon-like peptide 1... |
| Application: | GLP-1 derivative |
| MW: | 4141.7 D |
From 169.00€
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NEW
LipidLaunch(TM) SM-102 LNP (naked mole-rat cGAS)
Item number: Cay44929-5
An SM-102-based LNP solution for expressing naked mole-rat cGAS, composed of SM-102, cholesterol, 1,2-DSPC, and DMG-PEG(2000) at a molar ratio of 50:38.5:10:1.5 and encapsulating mRNA encoding His-tagged naked mole-rat cGAS, intended for the overexpression of His-tagged naked mole-rat cGAS in vitro and can be used...
| Application: | SM-102-based LNP solution for expressing naked mole-rat cGAS |
673.00€
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NEW
Taraxerol
Item number: Cay40136-1
A pentacyclic triterpene with diverse biological activities, reduces proliferation of MDA-MB-468 and SK-BR-3 breast cancer cells (IC50s = 100.5 µM and 84.48 µM, respectively), inhibits Nrf2, promotes degradation of GPX4, and induces ferroptosis in MDA-MB-468 and SK-BR-3 cells, reduces tumor growth in an SK-BR-3...
| Keywords: | 3beta-Taraxerol, Alnulin, Skimmiol, 13alpha-methyl-27-norolean-14-en-3beta-ol |
| Application: | Bioactive pentacyclic triterpene |
| CAS | 127-22-0 |
| MW: | 426.72 D |
From 75.00€
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NEW
YK-712
Item number: Cay43736-1
An ionizable cationic lipid, has been used in the generation of LNPs for the delivery of mRNA in vitro and in vivo, intramuscular administration of YK-712-containing LNPs encapsulating OVA-encoding mRNA accumulate primarily in the liver in mice, while YK-712-TLR-LNPs accumulate primarily in the spleen, intramuscular...
| Keywords: | 8-[[5-(2-decyl-1,3-dioxolan-4-yl)pentyl](2-hydroxyethyl)amino]-octanoic acid, 1-octylnonyl ester |
| Application: | Ionizable cationic lipid, LNP generation |
| CAS | 2965384-81-8 |
| MW: | 724.21 D |
From 115.00€
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NEW
BSA-Docosahexaenoate Polyunsaturated Fatty Acid Complex...
Item number: Cay44865-5
A BSA complex with DHA, has been used for efficient fatty acid delivery to cells in culture for monitoring fatty acid oxidation or similar processes in various cellular metabolic studies. SMILES: . InChi Code: . InChi Key:
| Keywords: | Bovine Serum Albumin-Docosahexaenoate, BSA-DHA |
| Application: | DHA-BSA complex, cell culture |
286.00€
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NEW
LipidLaunch(TM) SM-102 LNP (human cGAS)
Item number: Cay44930-5
An SM-102-based LNP solution for expressing human cGAS, composed of SM-102, cholesterol, 1,2-DSPC, and DMG-PEG(2000) at a molar ratio of 50:38.5:10:1.5 and encapsulating mRNA encoding His-tagged human cGAS, intended for the overexpression of His-tagged human wild-type cGAS in vitro and can be used in a variety of...
| Application: | SM-102-based LNP solution for expressing human cGAS |
673.00€
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Lipid S4 (hydrochloride)
Item number: Cay44984-1
An ionizable cationic lipid for LNP brain targeting, has been used in the generation of LNPs for the delivery of mRNA in vitro and in vivo, contains the 5-HT3 ligand SR-527227, which allows lipid S4-based LNPs to be targeted to the brain, lipid S4 LNPs containing lipid S4 and encapsulating mRNA encoding GFP...
| Keywords: | di(octan-3-yl) 9,9'-((6-((1-(6-chloropyridin-2-yl)piperidin-4-yl)amino)-6-oxohexyl)azanediyl)dinonanoate, monohydrochloride |
| Application: | Ionizable cationic lipid, brain targeting LNP generation |
| MW: | 898.19 D |
From 130.00€
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NEW
ALC-0307
Item number: Cay45037-1
An ionizable cationic lipid, has been used in the generation of LNPs for the delivery of mRNA in vitro and in vivo, radiolabeled ALC-0307-containing, CD4 antibody-conjugated LNPs encapsulating mRNA encoding luciferase selectively bind to CD4+ T cells in vitro, intravenous administration of ALC-0307-containing, CD4...
| Keywords: | di(heptadecan-9-yl) 8,8'-((3-(dimethylamino)propyl)azanediyl)dioctanoate |
| Application: | Ionizable cationic lipid, LNP generation |
| CAS | 2985009-50-3 |
| MW: | 863.5 D |
From 67.00€
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NEW
1-Palmitoleoyl-2-vaccenoyl-rac-glycero-3-phosphoethanolamine
Item number: Cay45071-1
A phospholipid. SMILES: OP(OCC(OC(CCCCCCCCC/C=C\CCCCCC)=O)COC(CCCCCCC/C=C\CCCCCC)=O)(OCCN)=O. InChi Code:...
| Keywords: | 1-(9(Z-Hexadecenoyl)-2-(11(Z)-octadecenoyl)-rac-glycero-3-phosphoethanolamine, 1-Palmitoleoyl-2-vaccenoyl... |
| Application: | Phospholipid |
| CAS | 1832660-38-4 |
| MW: | 715.99 D |
From 52.00€
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NEW
1-Palmitoyl-2-erucoyl-sn-glycero-3-phosphoethanolamine
Item number: Cay45089-1
A phospholipid. SMILES: O=P(OCC[NH3+])([O-])OC[C@H](OC(CCCCCCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O. InChi Code:...
| Keywords: | 1-Hexadecanoyl-2-(13(Z)-docosenoyl)-sn-glycero-3-phosphoethanolamine, 1-Palmitoyl-2-erucoyl Phosphatidylethanolamine,... |
| Application: | Phospholipid |
| CAS | 158957-33-6 |
| MW: | 774.12 D |
From 57.00€
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NEW
3(R)-hydroxy Palmitic Acid
Item number: Cay45136-10
A hydroxy fatty acid, component of lipid A and plipastatin A1. SMILES: OC(C[C@H](O)CCCCCCCCCCCCC)=O. InChi Code: InChI=1S/C16H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15(17)14-16(18)19/h15,17H,2-14H2,1H3,(H,18,19)/t15-/m1/s1. InChi Key: CBWALJHXHCJYTE-OAHLLOKOSA-N
| Keywords: | D-3-hydroxy Hexadecanoic Acid, D-3-hydroxy Palmitic Acid, FA 16:0,O, NSC 179484, (3R)-3-hydroxy-hexadecanoic acid |
| Application: | Hydroxy fatty acid |
| CAS | 20595-04-4 |
| MW: | 272.43 D |
From 75.00€
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DSPE-PEG(2000)-tetrazine
Item number: Cay45240-1
A PEGylated and clickable form of DSPE, has been used in the generation of LNPs for the delivery of small molecules in vitro and in vivo, LNPs containing DSPE-PEG(2000)-tetrazine and encapsulating SN-38 decrease the viability of HER2-overexpressing NIH3T6.7 cells pre-incubated with trans-cyclooctene-conjugated...
| Keywords: | DSPE-PEG(2000)-Tz,... |
| Application: | PEGylated, clickable DSPE, LNP generation |
| CAS | 3101670-39-4 |
From 134.00€
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