Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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MEL-A
MEL-A

Item number: Cay33858-1

MEL-A is a glycolipid biosurfactant that is produced from vegetable oils by Pseudozyma yeasts. Mixtures of MEL-A isoforms have been used as moisturizing agents in cosmetics, as well as to improve the low-temperature fluidity of biodiesel and hydrocarbon fuels. This product is a mixture of MEL-A isoforms with...
Keywords: Mannosylerythritol Lipid A,...
Application: Glycolipid biosurfactant
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8-iso-15-keto Prostaglandin F2alpha
8-iso-15-keto Prostaglandin F2alpha

Item number: Cay16390-50

8-iso-15-keto Prostaglandin F2alpha (8-iso-15-keto PGF2alpha) is a metabolite of the isoprostane 8-iso PGF2alpha in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2alpha) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2alpha is...
Keywords: 8-epi-15-keto PGF2alpha, 8-iso-15-keto PGF2alpha, 9alpha,11alpha-dihydroxy-15-oxo-(8beta)-prosta-5Z,13E-dien-1-oic acid
Application: 8-iso PGF2alpha metabolite, vasoconstrictor
CAS 191919-01-4
MW: 352.5 D
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10(E),12(Z)-Conjugated Linoleic Acid-d7
10(E),12(Z)-Conjugated Linoleic Acid-d7

Item number: Cay26482-1

Solulibility: Ethanol: Sparingly Soluble: 1-10 mg/ml: .
Keywords: 10(E),12(Z)-Octadecadienoic Acid-d7, 10E,12Z-CLA-d7, FA 18:2-d7, t10,c12-CLA-d7, trans-10,cis-12-Conjugated Linoleic...
Application: PPAR alpha agonist
MW: 287.49 D
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Leukotriene B4-d4
Leukotriene B4-d4

Item number: Cay320110-10

Leukotriene B4-d4 (LTB4-d4) is intended for use as an internal standard for the quantification of LTB4 (Cay-20110) by GC- or LC-MS. LTB4 is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion...
Keywords: LTB4-d4, 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic-6,7,14,15-d4 acid
Application: Standard
CAS 124629-74-9
MW: 340.5 D
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beta-Cortol
beta-Cortol

Item number: Cay33412-5

beta-Cortol is an endogenous metabolite of cortisol (hydrocortisone, Cay-20739). It is formed from cortisol via the intermediate metabolite 5beta-tetrahydrocortisol, which is dehydrogenated by 20beta-hydroxysteroid dehydrogenase (20beta-HSD) in the liver to produce beta-cortol. Urinary levels of beta-cortol have...
Keywords: NSC 58792, 5beta-pregnane-3alpha,11beta,17,20R,21-pentol
Application: Endogenous cortisol metabolite, obesity marker
CAS 667-65-2
MW: 368.51 D
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Docosahexaenoyl-L-carnitine (chloride)
Docosahexaenoyl-L-carnitine (chloride)

Item number: Cay38350-1

Docosahexaenoyl-L-carnitine is a long-chain acylcarnitine composed of docosahexaenoic acid (DHA, Cay-90310) and L-carnitine (Cay-21489). Decreased venous cord plasma levels of docosahexaenoyl-L-carnitine are associated with babies born small for gestational age.Formal Name:...
Keywords: C22:6 Carnitine, CAR 22:6, L-Carnitine cervonoyl ester, L-Cervonoylcarnitine,...
Application: Long-chain acylcarnitine
MW: 508.13 D
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503O13
503O13

Item number: Cay38628-10

503O13 is an ionizable cationic lipidoid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vivo. LNPs containing 503O13 and encapsulating siRNA targeting mRNA encoding Factor VII decrease serum Factor VII levels in mice.. Solulibility: Ethanol: Soluble: Methanol: Soluble.
Keywords: 7,11-dimethyl-4,14-bis[3-oxo-3-(tridecyloxy)propyl]-4,7,11,14-tetraazaheptadecanedioic acid, 1,17-ditridecyl ester
Application: Ionizable cationic lipidoid, LNP formation
CAS 1566560-20-0
MW: 1206 D
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Lipid 114
Lipid 114

Item number: Cay41158-1

Lipid 114 is an ionizable cationic lipid (pKa = ~6.8) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vitro and in vivo. Lipid 114-containing LNPs accumulate in the liver and, to a lesser extent, the kidneys in mice. LNPs containing lipid 114 and encapsulating siRNA...
Keywords: ditetradecyl 4,8,17-tris(3-oxo-3-(tetradecyloxy)propyl)-4,8,13,17-tetraazaicosanedioate
Application: Ionizable cationic lipid, LNP formation
MW: 1544.51 D
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A28-C6B2
A28-C6B2

Item number: Cay42017-1

A28-C6B2 is an ionizable cationic lipid (pKa = 6.43) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. LNPs containing A28-C6B2 accumulate primarily in the spleen in mice after intravenous administration and target F4/80+ macrophages, Cd11c+ dendritic cells, and to...
Keywords: bis(2-butyloctyl) 6,6'-((5-hydroxypentyl)azanediyl)dihexanoate
Application: Ionizable cationic lipid, LNP formation
MW: 668.09 D
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Phocaecholic Acid
Phocaecholic Acid

Item number: Cay42499-1

Phocaecholic acid is a bile acid that has been found in duck (A. platyrhynchos) bile.. Solulibility: DMSO: Soluble: =10 mg/ml: Ethanol: Soluble: =10 mg/ml.
Keywords: (23R)-hydroxy CDCA, (23R)-hydroxy Chenodeoxycholic Acid, PhCA, beta-Phocaecholic Acid,...
Application: Bile acid
CAS 105369-89-9
MW: 408.57 D
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Si5-N14
Si5-N14

Item number: Cay42520-1

Si5-N14 is a siloxane-incorporated ionizable cationic lipidoid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA and single-guide RNA (sgRNA) in vitro and in vivo. LNPs containing Si5-N14 and encapsulating a luciferase mRNA reporter exhibit increased cellular uptake via...
Keywords: 3,3',3'',3'''-(((1,1,3,3-tetramethyldisiloxane-1,3-diyl)bis(propane-3,1-diyl))bis(azanetriyl))tetrakis(N-tetradecylpropana...
Application: Siloxane-incorporated ionizable cationic lipidoid, LNP formation
CAS 3006860-57-4
MW: 1318.31 D
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Anti-NASH Agent 1
Anti-NASH Agent 1

Item number: Cay42614-10

Anti-NASH agent 1 is an anti-non-alcoholic steatohepatitis (NASH) agent and a derivative of the PPARalpha and PPARdelta agonist GFT505 (elafibranor, Cay-23508). It inhibits free fatty acid-induced triglyceride accumulation and aspartate aminotransferase (AST) activity in HepG2 cells when used at a concentration of...
Keywords: Anti-Non-Alcoholic Steatohepatitis Agent 1,...
Application: Anti-NASH (anti-non-alcoholic steatohepatitis) agent
CAS 2409685-41-0
MW: 423.6 D
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