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Leukotriene D4
Item number: Cay20310-25
Leukotriene D4 (LTD4) is an active metabolite of LTC4 (Cay-20210) and a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is formed via metabolism of LTC4 by gamma-glutamyl transpeptidase. Like LTC4, LTD4 (0.01-0.1 pM) induces contractions in isolated guinea pig parenchymal strips and tracheal...
| Keywords: | LTD4, 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 73836-78-9 |
| MW: | 496.7 D |
From 231.00€
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Fingolimod (hydrochloride)
Item number: Cay10006292-50
Fingolimod is an immune modulator, a prodrug form of the sphingosine-1-phosphate (S1P) receptor agonist FTY720 phosphate (Cay-10008639), and a derivative of myriocin (Cay-63150). It selectively inhibits calcium-dependent cytosolic phospholipase A2 (cPLA2) over calcium-independent PLA2 (iPLA2) and secretory PLA2...
| Keywords: | FTY720, 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, hydrochloride |
| Application: | Immune Modulator |
| CAS | 162359-56-0 |
| MW: | 343.9 D |
From 112.00€
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Thromboxane B2-d4
Item number: Cay319030-25
Thromboxane B2-d4 (TXB2-d4) is intended for use as an internal standard for the quantification of TXB2 (Cay-19030) by GC- or LC-MS. TXB2 is a non-enzymatically derived, stable, inactive metabolite of TXA2, which is highly unstable. Serum levels of TXB2 positively correlate with platelet COX-1 activation. Urinary...
| Keywords: | TXB2-d4, 9alpha,11,15S-trihydroxy-thromba-5Z,13E-dien-1-oic-3,3,4,4-d4 acid |
| Application: | Standard |
| CAS | 1346112-79-5 |
| MW: | 374.5 D |
From 271.00€
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Leukotriene C4
Item number: Cay20210-25
Leukotriene C4 (LTC4) is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A)...
| Keywords: | LTC4, 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 72025-60-6 |
| MW: | 625.8 D |
From 231.00€
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13,14-dihydro-15-keto Prostaglandin D2
Item number: Cay12610-1
13,14-dihydro-15-keto Prostaglandin D2 (13,14-dihydro-15-keto PGD2) is a metabolite of PGD2 (Cay-12010) which is formed through the 15-hydroxy PGDH pathway. 13,14-dihydro-15-keto PGD2 was recently identified as a selective agonist for the CRTH2/DP2 receptor. It also inhibits ion flux in a canine colonic mucosa...
| Keywords: | 13,14-dihydro-15-keto PGD2, 9alpha-hydroxy-11,15-dioxo-prost-5Z-en-1-oic acid |
| Application: | CRTH2 receptor agonist, DP2 receptor agonist |
| CAS | 59894-07-4 |
| MW: | 352.5 D |
From 193.00€
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5(S)-HETE-d8
Item number: Cay334230-25
5(S)-HETE-d8 is intended for use as an internal standard for the quantification of 5-HETE by GC- or LC-MS. (±)5-HETE is formed via non-enzymatic oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). 5(S)- and 5(R)-HETE are formed by lipoxygenase-mediated oxidation of arachidonic acid.Formal Name:...
| Keywords: | 5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid |
| Application: | Standard |
| CAS | 330796-62-8 |
| MW: | 328.5 D |
From 295.00€
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6-keto Prostaglandin F1alpha
Item number: Cay15210-1
6-keto Prostaglandin F1alpha (6-keto PGF1alpha) is the inactive, non-enzymatic hydrolysis product of PGI2. 6-keto PGF1alpha serves as a useful marker of PGI2 biosynthesis in vivo. When [3H]-PGI2 is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [3H]-6-keto PGF1alpha.Formal...
| Keywords: | 6-keto PGF1alpha, 6-oxo-9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 58962-34-8 |
| MW: | 370.5 D |
From 145.00€
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Tafluprost
Item number: Cay10005440-25
Tafluprost is a prodrug form of the FP receptor agonist tafluprost (free acid) (Cay-10005439) and a derivative of prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020). It decreases pupillary diameter in cats when applied topically at doses of 0.0001 or 0.001% v/v. Ocular administration of tafluprost (0.0005% v/v)...
| Keywords: | AFP-168, 15,15-difluoro-9alpha,11alpha-dihydroxy-16-phenoxy-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, isopropyl... |
| Application: | FP receptor agonist |
| CAS | 209860-87-7 |
| MW: | 452.5 D |
From 147.00€
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PAF C-16
Item number: Cay60900-5
PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways. It is a potent mediator of neutrophil migration, and the production of reactive oxygen species, and IL-6 in human macrophages. It is a more potent mediator of...
| Keywords: | Platelet-activating Factor C-16, 1-O-hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine |
| Application: | Bioactive lipid assays |
| CAS | 74389-68-7 |
| MW: | 523.7 D |
From 54.00€
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15(S)-HETE-d8
Item number: Cay334720-25
15(S)-HETE-d8 is intended for use as an internal standard for the quantification of 15(S)-HETE (Cay-34720) by GC- or LC-MS. (±)15-HETE and 15(S)-HETE are formed via non-enzymatic and 15-lipoxygenase-mediated oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607), respectively. 15(R)-HETE is formed by...
| Keywords: | 15(S)-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid |
| Application: | Standard |
| CAS | 84807-87-4 |
| MW: | 328.5 D |
From 265.00€
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NEW
RO3244794
Item number: Cay25350-1
An IP receptor antagonist (Ki = 20 nM in isolated human platelets), selective for the IP receptor over a panel of 50 receptors at 10 µM but does bind to EP3, EP4, and TP receptors and the adenosine A3 receptor (Kis = 4,169, 1,820, 8,128, and 4,786 nM, respectively), inhibits carbaprostacyclin-induced cAMP...
| Keywords: | 4-fluoro-N-[[[5-(4-fluorophenyl)-2-benzofuranyl]methoxy]carbonyl]-D-phenylalanine |
| Application: | IP receptor antagonist |
| CAS | 361457-01-4 |
| MW: | 451.42 D |
From 227.00€
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NEW
BSA-NBD-Palmitate Saturated Fatty Acid Complex (1 mM)
Item number: Cay44501-5
A BSA complex with NBD-palmitic acid, can be used for efficient fatty acid delivery to cells in culture for the purpose of monitoring fatty acid oxidation or similar processes in various cellular metabolic studies, can be used to visualize lipid uptake using fluorescence microscopy. SMILES: . InChi Code: . InChi Key:
| Keywords: | Bovine Serum Albumin-NBD-PA, Bovine Serum Albumin-NBD-Palmitate, BSA-NBD-PA |
| Application: | BSA, NBD-palmitic acid complex, cell culture |
309.00€
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