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Pregnanolone
Item number: Cay42751-1
Pregnanolone is a neurosteroid and an active metabolite of pregnenolone (Cay19864). It is formed from pregnenolone via the intermediates progesterone (Cay15876) and 5beta-dihydroprogesterone (Cay34644). Pregnanolone enhances the binding of flunitrazepam to GABAA receptors in rat brain homogenate (EC50 = 237 nM) and...
| Keywords: | 3alpha,5beta-P, 3alpha,5beta-Tetrahydroprogesterone, 5beta-Pregnan-3alpha-ol-20-one, Eltanolone, NSC 82867, SKF 6455,... |
| Application: | Pregnenolone active metabolite, neurosteroid |
| CAS | 128-20-1 |
| MW: | 318.5 D |
From 51.00€
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Androst-5-enediol Sulfate (sodium salt)
Item number: Cay43450-1
Androst-5-enediol sulfate is a metabolite of 5-androstenediol. SMILES C[C@]12C(C[C@@H](OS([O-])(=O)=O)CC2)=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4O.[Na+] InChi Code...
| Keywords: | 5-Androstenediol 3-sulfate, androst-5-ene-3beta,17beta-diol, 3-(hydrogen sulfate), monosodium salt |
| Application: | 5-Androstenediol metabolite |
| CAS | 131211-33-1 |
| MW: | 392.49 D |
From 147.00€
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5beta-Cholanic Acid-3,7-dione
Item number: Cay43575-1
5beta-Cholanic acid-3,7-dione is a synthetic bile acid. It decreases bile volume and bile levels of cholic acid and cholesterol in rabbits when administered at a dose of 5 mg/kg. SMILES C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](CC(CC4)=O)([H])CC3=O)C InChi Code...
| Keywords: | 3,7-Diketochenodeoxycholic Acid, 3,7-Dioxo-5beta-cholan-24-oic Acid, Dehydrochenodeoxycholic Acid,... |
| Application: | Synthetic bile acid |
| CAS | 859-97-2 |
| MW: | 388.55 D |
From 45.00€
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Ganglioside GD3 . disodium salt (bovine brain)
Item number: AG-CN2-9005-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Keywords: | GD3 . 2Na, Disialoganglioside GD3 . 2Na |
| Application: | Acidic glycosphingolipid |
| CAS | 62010-37-1 |
| MW: | 1470,8 D |
From 226.00€
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1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC
Item number: Cay10009864-10
1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Cay-10011298) and arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques....
| Keywords: | 18:0/20:4-PC, 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-Phosphatidylcholine,... |
| Application: | Bioactive lipid assays |
| CAS | 35418-59-8 |
| MW: | 810.1 D |
From 126.00€
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Arachidonic Acid Oxylipin MaxSpec(R) LC-MS Mixture
Item number: Cay20666-1
The Arachidonic Acid Oxylipin MaxSpec(R) LC-MS Mixture contains oxylipin metabolites derived from arachidonic acid (Item No 90010). The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct use in LC-MS...
| Application: | MS |
810.00€
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Arachidic Acid
Item number: Cay9000339-50
Arachidic acid is a long-chain saturated fatty acid that has been found in peanut butter and anaerobic fungi. It inhibits rabbit neutrophil aggregation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP, Cay-21495) when used at a concentration of 5 µM. Formulations containing arachidic acid have been used as...
| Keywords: | n-Eicosanoic Acid, Arachic Acid, C20:0, Icosanoic Acid, NSC 93983, eicosanoic acid |
| Application: | Bioactive lipid assays |
| CAS | 506-30-9 |
| MW: | 312.5 D |
From 37.00€
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TY 52156
Item number: Cay19119-5
TY 52156 is a selective sphingosine-1-phosphate receptor 3 (SIP3) antagonist (Ki = 110 nM). It preferentially inhibits the S1P-induced increase in intracellular calcium in Chinese hamster ovary cells expressing S1P3 over cell expressing S1P1, S1P2, or S1P4. TY 52156 has been shown to suppress FTY720-induced S1P3...
| Keywords: | N-(4-chlorophenyl)-3,3-dimethyl-2-oxobutanimidic acid, 2-(4-chlorophenyl)hydrazide |
| Application: | S1PR3 antagonist |
| CAS | 934369-14-9 |
| MW: | 364.3 D |
From 51.00€
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Hyodeoxycholic Acid
Item number: Cay20294-5
Hyodeoxycholic acid (HDCA) is a secondary bile acid. It is produced from lithocholic acid (Cay-20253) by gut bacteria. Dietary administration of HDCA (1.25% w/w) decreases plasma VLDL and LDL cholesterol levels and reduces fasting glucose levels and atherosclerotic lesion size in LDL receptor knockout mice fed a...
| Keywords: | HDCA, NSC 60672, alpha-Hyodeoxycholic Acid, (5beta)-3alpha,6alpha-dihydroxy-cholan-24-oic acid |
| Application: | Secondary bile acid |
| CAS | 83-49-8 |
| MW: | 392.6 D |
From 89.00€
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C22 Sphingomyelin (d18:1/22:0)
Item number: Cay24451-500
C22 Sphingomyelin is a naturally occurring form of sphingomyelin (Cay-22674, Cay-24345). Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyelin levels are decreased in T-47D mammary epithelial cells and increased in...
| Keywords: | N-docosanoyl-D-erythro-Sphingosylphosphorylcholine, SM(d18:1/22:0), Sphingomyelin (d18:1/22:0),... |
| CAS | 94359-12-3 |
| MW: | 787.2 D |
485.00€
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5(S)-HEPE
Item number: Cay32210-25
5(S)-HEPE is an active metabolite of eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). It is formed from EPA by 5-lipoxygenase (5-LO). 5(S)-HEPE is an agonist of G protein-coupled receptor 119 (GPR119). It increases cAMP accumulation in CHO-K1 cells expressing human GPR119 when used at a concentration...
| Keywords: | 5S-hydroxy-6E,8Z,11Z,14Z,17Z-eicosapentaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 92008-51-0 |
| MW: | 318.5 D |
From 180.00€
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(±)11-HEPE
Item number: Cay32500-25
(±)11-HEPE is produced by non-enzymatic oxidation of eicosapentaenoic acid. It contains equal amounts of 11(S)-HEPE and 11(R)-HEPE. The biological activity of (±)11-HEPE has not been clearly documented.Formal Name: (±)-11-hydroxy-5Z,8Z,12E,14Z,17Z-eicosapentaenoic acid. CAS Number: 99217-78-4. Molecular Formula:...
| Keywords: | (±)-11-hydroxy-5Z,8Z,12E,14Z,17Z-eicosapentaenoic acid |
| Application: | Bioactive lipid studies |
| CAS | 99217-78-4 |
| MW: | 318.5 D |
From 180.00€
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