No results were found for the filter!
Lipid-based Drug Delivery Tools
1,2-Dioleoyl-sn-glycero-3-PE
Item number: Cay15091-100
1,2-Dioleoyl-sn-glycero-3-PE (1,2-DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. The compound features the same diacylglycerol stereochemistry as that of the natural compound. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex...
| Keywords: | 1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine, 1,2-DOPE, 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine |
| Application: | Emulsifier |
| CAS | 4004-05-1 |
| MW: | 744.1 D |
From 137.00€
*
Glycolithocholic Acid
Item number: Cay21723-1
Glycolithocholic acid is a glycine-conjugated form of the secondary bile acid lithocholic acid (Cay-20253). It is increased in the liver of mice fed a diet supplemented with ursodeoxycholic acid (Cay-15121). Glycolithocholic acid levels are decreased in the plasma following subcutaneous administration of...
| Keywords: | Lithocholylglycine, N-[(3alpha,5beta)-3-hydroxy-24-oxocholan-24-yl]-glycine |
| CAS | 474-74-8 |
| MW: | 433.6 D |
From 69.00€
*
C24:1 Ceramide (d18:1/24:1(15Z))
Item number: Cay62530-1
Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase. C24:1 Ceramide (d18:1/24:1(15Z)) is one of the most abundant naturally occurring ceramides. Ceramides mediate many diverse biological activities, as has been demonstrated in studies...
| Keywords: | Cer(d18:1/24:1(15Z)), Ceramide (d18:1/24:1(15Z)), Nervonic Ceramide, N-Nervonoyl-D-erythro-Sphingosine,... |
| Application: | Bioactive lipid assays |
| CAS | 54164-50-0 |
| MW: | 648.1 D |
From 51.00€
*
(±)13-HpODE
Item number: Cay10704-100
(±)13-HpODE is a racemic mixture of hydroperoxides derived non-enzymatically from linoleic acid through the action of reactive oxygen species. Lipid hydroperoxides, including 13-HpODE, have limited direct biological actions, such as the activation of lipoxygenases. Normally, (±)13-HpODE is rapidly reduced to...
| Keywords: | (±)13-hydroperoxy-9Z,11E-octadecadienoic acid |
| Application: | Bioactive lipid studies |
| CAS | 23017-93-8 |
| MW: | 312.4 D |
From 154.00€
*
Laurdan
Item number: Cay19706-10
Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of laurdan can be used to identify phospholipid phase. When excited at 340 nm, GP values are 0.6 and -0.2 for gel...
| Keywords: | 1-[6-(dimethylamino)-2-naphthalenyl]-1-dodecanone |
| Application: | Membrane permeable fluorescent probe, GP quantitation |
| CAS | 74515-25-6 |
| MW: | 353.5 D |
From 73.00€
*
omega-3 Arachidonic Acid
Item number: Cay90011-1
omega-3 Arachidonic acid is a rare PUFA found in trace amounts in dietary sources. omega-3 Fatty acids are now known to be essential for infant growth and development and protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders. In human platelet membranes, omega-3...
| Keywords: | omega-3 AA, 8Z,11Z,14Z,17Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 24880-40-8 |
| MW: | 304.5 D |
From 104.00€
*
Phosphatidylglycerol (egg) (sodium salt)
Item number: Cay25846-500
Phosphatidylglycerol is a naturally occurring anionic phospholipid and a constituent of plant, animal, and bacterial cell membranes. It is less abundant than phosphatidylethanolamine (Cay-16878, Cay-24332) in prokaryotes and eukaryotes and phosphatidylcholine (Cay-24343, Cay-24370) in eukaryotes. It is formed via a...
| Keywords: | L-alpha-Phosphatidylglycerols (egg), PGs (egg) |
| Application: | Phosphatidylglycerol mixture, membrane phospholipid |
| CAS | 383907-64-0 |
From 110.00€
*
Docosahexaenoic Acid (peroxide free)
Item number: Cay17932-10
Docosahexaenoic acid (DHA) is a long-chain omega-3 polyunsaturated fatty acid (PUFA) found in fish and algal oils. It comprises approximately 40% of total brain PUFAs and is abundant in grey matter and retinal membranes. DHA typically represents 0.52-7.5% of human total plasma fatty acids. It is produced from...
| Keywords: | 4,7,10,13,16,19-Docosahexaenoic Acid, C22:6 n-3, C22:6(4Z,7Z,10Z,13Z,16Z,19Z), Cervonic Acid, DHA,... |
| Application: | Long-chain omega-3 PUFA |
| CAS | 6217-54-5 |
| MW: | 328.5 D |
From 40.00€
*
C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)
Item number: Cay24879-1
C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide (Cay-24870, Cay-24871, Cay-24872) that contains an adamantanyl group in place of the fatty acyl chain. It inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay when used at a...
| Keywords: | AdaGb3, Adamantyl Gb3, C2 Adamantanyl Ceramide Trihexoside (d18:1/2:0),... |
| Application: | Bioactive sphingolipid |
| CAS | 261155-87-7 |
| MW: | 962.17 D |
651.00€
*
Aranidipine
Item number: Cay40813-10
Aranidipine is an antagonist of voltage-gated calcium channel Cav3.2. It inhibits inward currents in Xenopus oocytes expressing human Cav3.2 channels when used at a concentration of 10 µM. Aranidipine (10 mg/kg) decreases mean blood pressure and increases heart rate in spontaneously hypertensive rats (SHRs). It...
| Keywords: | MPC-1304, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-yridinedicarboxylic acid, 3-methyl 5-(2-oxopropyl) ester |
| Application: | Cav3.2 antagonist |
| CAS | 86780-90-7 |
| MW: | 388.4 D |
From 76.00€
*
Grayanotoxin I
Item number: Cay42644-100
Grayanotoxin I is a diterpene toxin that has been found in R. ponticum nectar, a component of mad honey. It increases resting sodium permeability in squid axonal membranes when used at a concentration of 10 µM. Grayanotoxin I (0.25, 0.5, and 1 mg/kg) induces proteinuria and reduces serum levels of alanine...
| Keywords: | Acetylandromedol, Andromedotoxin, Asebotoxin, GTX I, NSC 26711, Rhodotoxin, grayanotoxane-3beta,5,6beta,10,14R,16-hexol,... |
| Application: | Diterpene toxin, reversible Nav1.x agonist |
| CAS | 4720-09-6 |
| MW: | 412.52 D |
From 193.00€
*
Pseudoginsenoside RT5
Item number: Cay42388-1
Pseudoginsenoside RT5 is an ocotillol-type ginsenoside that has been found in P. quinquefolium. SMILES C[C@]12[C@]3([C@@]([C@@H](C[C@]1([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])[C@H](C2)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO)C)O)([H])[C@]([C@]6(O[C@H](CC6)C(C)(O)C)C)([H])CC3)C InChi Code...
| Keywords: | 24(R)-Pseudoginsenoside RT5, Ginsenoside RT-5, (3beta,6alpha,12beta,24R)-20,24-epoxy-3,12,25-trihydroxydammaran-6-yl,... |
| Application: | Ginsenoside |
| CAS | 98474-78-3 |
| MW: | 654.87 D |
From 58.00€
*