No results were found for the filter!
Prostaglandin E2-1-glyceryl ester
Item number: Cay10140-1
2-Arachidonoyl glycerol (2-AG, Cay-62160) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures and isolated enzyme preparations results in...
| Keywords: | PGE2-1-glyceryl ester, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, 1-glyceryl ester |
| Application: | Bioactive lipid assays |
| CAS | 37497-47-5 |
| MW: | 426.6 D |
From 137.00€
*
(±)5(6)-DiHETE
Item number: Cay10467-25
Eicosapentaenoic acid (EPA, Cay-90110) is an omega-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils. EPA is metabolized, in part, through cytochrome P450-catalyzed epoxidation followed by conversion to the vicinal diols by epoxide hydrolases. (±)5(6)-DiHETE is a possible metabolite...
| Keywords: | (±)5,6-dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic acid |
| Application: | Metabolic studies |
| CAS | 845673-97-4 |
| MW: | 336.5 D |
From 162.00€
*
Palmitoleoyl Ethanolamide
Item number: Cay10965-5
N-acylethanolamines (NAEs) are lipid-derived signaling compounds. For example, arachidonoyl ethanolamide is an endogenous cannabinoid (CB) that activates the CB1 and CB2 receptors. Palmitoleoyl Ethanolamide (POEA) is an NAE that is produced endogenously from palmitoleic acid. Unlike arachidonoyl ethanolamide and...
| Keywords: | POEA, N-(2-hydroxyethyl)-9Z-hexadecenamide |
| Application: | Standard |
| CAS | 94421-67-7 |
| MW: | 297.5 D |
From 97.00€
*
(±)16(17)-DiHDPA
Item number: Cay18176-50
(±)16(17)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid (DHA, Cay-90310). It has been shown to inhibit VEGF-induced angiogenesis and reduce cancer cell metastasis in mice.Formal Name: (±)16,17-dihydroxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid. CAS Number: 1345275-27-5. Molecular...
| Keywords: | (±)16,17-dihydroxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid |
| Application: | Angiogenesis inhibitor |
| CAS | 1345275-27-5 |
| MW: | 362.5 D |
From 132.00€
*
C20 Sphingomyelin (d18:1/20:0)
Item number: Cay24450-500
C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin (Cay-13104) and in human plasma where it is positively correlated with insulin resistance in obese humans. C20 sphingomyelin is also upregulated in...
| Keywords: | N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine, SM(d18:1/20:0),... |
| Application: | Naturally occurring sphingolipid |
| CAS | 121999-68-6 |
| MW: | 759.2 D |
485.00€
*
15-deoxy-Delta12,14-Prostaglandin J2-d4
Item number: Cay318570-25
15-deoxy-Delta12,14-PGJ2-d4 contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 15-deoxy-Delta12,14-PGJ2 by GC- or LC-mass spectrometry. 15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is a metabolite of PGJ2....
| Keywords: | 15-deoxy-Delta12,14-PGJ2-d4, 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic-3,3,4,4-d4 acid |
| Application: | Standard |
| CAS | 1542166-82-4 |
| MW: | 320.5 D |
From 151.00€
*
(±)11-HDHA
Item number: Cay33450-25
(±)11-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. DHA is metabolized to 11(S)-HDHA by human platelets and canine retina. In addition to 11(S)-HDHA, 14(S)-HDHA is also produced by platelets....
| Keywords: | (±)11-HDoHE, 11-hydroxy Docosahexaenoic Acid, (±)11-hydroxy-4Z,7Z,9E,13Z,16Z,19Z-docosahexaenoic acid |
| Application: | Oxidative stress marker |
| CAS | 87018-59-5 |
| MW: | 344.5 D |
From 119.00€
*
Docosatetraenoyl Ethanolamide
Item number: Cay90385-5
Docosatetraenoyl ethanolamide (DEA) is an endocannabinoid containing docosatetraenoic acid in place of the arachidonate moiety of AEA. DEA acts on CB1 receptors with potency and efficacy similar to that of AEA. However, its specific role and relative importance as a cannabinergic neurotransmitter have not been...
| Keywords: | DEA, N-(2-hydroxyethyl)-7Z,10Z,13Z,16Z-docosatetraenamide |
| Application: | Bioactive lipid assays |
| CAS | 150314-35-5 |
| MW: | 375.6 D |
From 105.00€
*
Docosahexaenoic Acid ethyl ester
Item number: Cay9090310-100
Docosahexaenoic acid (DHA) ethyl ester is an esterified form of the omega-3 fatty acid DHA (Cay-90310, Cay-17950). DHA ethyl ester increases plasma and erythrocyte membrane DHA levels in rats without altering the content of the omega-6 fatty acid arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) when...
| Keywords: | Cervonic Acid ethyl ester, DHA ethyl ester, 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid, ethyl ester |
| Application: | Bioactive lipid assays |
| CAS | 81926-94-5 |
| MW: | 356.5 D |
From 69.00€
*
Pyrrophenone
Item number: Cay13294-500
The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes (LTs). Pyrrophenone inhibits cPLA2alpha with an IC50 of 4.2 nM...
| Keywords: | N-[[(2S,4R)-1-[2-(2,4-difluorobenzoyl)benzoyl]-4-[(triphenylmethyl)thio]-2-pyrrolidinyl]methyl]-4-[(Z)-(2,4-dioxo-5-thiazo... |
| Application: | cPLA2 inhibitor |
| CAS | 341973-06-6 |
| MW: | 850 D |
From 189.00€
*
25(S)-27-hydroxy Cholesterol
Item number: Cay14791-1
The liver x receptors (LXRalpha and LXRbeta) are nuclear hormone receptors whose native ligands, oxysterols, induce the expression of genes involved in cholesterol and fatty acid metabolism. 27-hydroxy Cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRalpha and LXRbeta in...
| Keywords: | (25S)-26-hydroxy cholesterol, (25S)-cholest-5-ene-3beta,26-diol |
| Application: | LXR alpha / beta activator |
| CAS | 56845-83-1 |
| MW: | 402.7 D |
From 89.00€
*
Lipid-based Drug Delivery Tools
1,2-Dioleoyl-sn-glycero-3-PE
Item number: Cay15091-100
1,2-Dioleoyl-sn-glycero-3-PE (1,2-DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. The compound features the same diacylglycerol stereochemistry as that of the natural compound. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex...
| Keywords: | 1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine, 1,2-DOPE, 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine |
| Application: | Emulsifier |
| CAS | 4004-05-1 |
| MW: | 744.1 D |
From 137.00€
*