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Docosatetraenoyl Ethanolamide
Item number: Cay90385-5
Docosatetraenoyl ethanolamide (DEA) is an endocannabinoid containing docosatetraenoic acid in place of the arachidonate moiety of AEA. DEA acts on CB1 receptors with potency and efficacy similar to that of AEA. However, its specific role and relative importance as a cannabinergic neurotransmitter have not been...
| Keywords: | DEA, N-(2-hydroxyethyl)-7Z,10Z,13Z,16Z-docosatetraenamide |
| Application: | Bioactive lipid assays |
| CAS | 150314-35-5 |
| MW: | 375.6 D |
From 105.00€
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Docosahexaenoic Acid ethyl ester
Item number: Cay9090310-100
Docosahexaenoic acid (DHA) ethyl ester is an esterified form of the omega-3 fatty acid DHA (Cay-90310, Cay-17950). DHA ethyl ester increases plasma and erythrocyte membrane DHA levels in rats without altering the content of the omega-6 fatty acid arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) when...
| Keywords: | Cervonic Acid ethyl ester, DHA ethyl ester, 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid, ethyl ester |
| Application: | Bioactive lipid assays |
| CAS | 81926-94-5 |
| MW: | 356.5 D |
From 69.00€
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Pyrrophenone
Item number: Cay13294-500
The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes (LTs). Pyrrophenone inhibits cPLA2alpha with an IC50 of 4.2 nM...
| Keywords: | N-[[(2S,4R)-1-[2-(2,4-difluorobenzoyl)benzoyl]-4-[(triphenylmethyl)thio]-2-pyrrolidinyl]methyl]-4-[(Z)-(2,4-dioxo-5-thiazo... |
| Application: | cPLA2 inhibitor |
| CAS | 341973-06-6 |
| MW: | 850 D |
From 189.00€
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25(S)-27-hydroxy Cholesterol
Item number: Cay14791-1
The liver x receptors (LXRalpha and LXRbeta) are nuclear hormone receptors whose native ligands, oxysterols, induce the expression of genes involved in cholesterol and fatty acid metabolism. 27-hydroxy Cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRalpha and LXRbeta in...
| Keywords: | (25S)-26-hydroxy cholesterol, (25S)-cholest-5-ene-3beta,26-diol |
| Application: | LXR alpha / beta activator |
| CAS | 56845-83-1 |
| MW: | 402.7 D |
From 89.00€
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Lipid-based Drug Delivery Tools
1,2-Dioleoyl-sn-glycero-3-PE
Item number: Cay15091-100
1,2-Dioleoyl-sn-glycero-3-PE (1,2-DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. The compound features the same diacylglycerol stereochemistry as that of the natural compound. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex...
| Keywords: | 1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine, 1,2-DOPE, 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine |
| Application: | Emulsifier |
| CAS | 4004-05-1 |
| MW: | 744.1 D |
From 137.00€
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Glycolithocholic Acid
Item number: Cay21723-1
Glycolithocholic acid is a glycine-conjugated form of the secondary bile acid lithocholic acid (Cay-20253). It is increased in the liver of mice fed a diet supplemented with ursodeoxycholic acid (Cay-15121). Glycolithocholic acid levels are decreased in the plasma following subcutaneous administration of...
| Keywords: | Lithocholylglycine, N-[(3alpha,5beta)-3-hydroxy-24-oxocholan-24-yl]-glycine |
| CAS | 474-74-8 |
| MW: | 433.6 D |
From 69.00€
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C24:1 Ceramide (d18:1/24:1(15Z))
Item number: Cay62530-1
Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase. C24:1 Ceramide (d18:1/24:1(15Z)) is one of the most abundant naturally occurring ceramides. Ceramides mediate many diverse biological activities, as has been demonstrated in studies...
| Keywords: | Cer(d18:1/24:1(15Z)), Ceramide (d18:1/24:1(15Z)), Nervonic Ceramide, N-Nervonoyl-D-erythro-Sphingosine,... |
| Application: | Bioactive lipid assays |
| CAS | 54164-50-0 |
| MW: | 648.1 D |
From 51.00€
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(±)13-HpODE
Item number: Cay10704-100
(±)13-HpODE is a racemic mixture of hydroperoxides derived non-enzymatically from linoleic acid through the action of reactive oxygen species. Lipid hydroperoxides, including 13-HpODE, have limited direct biological actions, such as the activation of lipoxygenases. Normally, (±)13-HpODE is rapidly reduced to...
| Keywords: | (±)13-hydroperoxy-9Z,11E-octadecadienoic acid |
| Application: | Bioactive lipid studies |
| CAS | 23017-93-8 |
| MW: | 312.4 D |
From 154.00€
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Laurdan
Item number: Cay19706-10
Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of laurdan can be used to identify phospholipid phase. When excited at 340 nm, GP values are 0.6 and -0.2 for gel...
| Keywords: | 1-[6-(dimethylamino)-2-naphthalenyl]-1-dodecanone |
| Application: | Membrane permeable fluorescent probe, GP quantitation |
| CAS | 74515-25-6 |
| MW: | 353.5 D |
From 73.00€
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omega-3 Arachidonic Acid
Item number: Cay90011-1
omega-3 Arachidonic acid is a rare PUFA found in trace amounts in dietary sources. omega-3 Fatty acids are now known to be essential for infant growth and development and protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders. In human platelet membranes, omega-3...
| Keywords: | omega-3 AA, 8Z,11Z,14Z,17Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 24880-40-8 |
| MW: | 304.5 D |
From 104.00€
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Phosphatidylglycerol (egg) (sodium salt)
Item number: Cay25846-500
Phosphatidylglycerol is a naturally occurring anionic phospholipid and a constituent of plant, animal, and bacterial cell membranes. It is less abundant than phosphatidylethanolamine (Cay-16878, Cay-24332) in prokaryotes and eukaryotes and phosphatidylcholine (Cay-24343, Cay-24370) in eukaryotes. It is formed via a...
| Keywords: | L-alpha-Phosphatidylglycerols (egg), PGs (egg) |
| Application: | Phosphatidylglycerol mixture, membrane phospholipid |
| CAS | 383907-64-0 |
From 110.00€
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Docosahexaenoic Acid (peroxide free)
Item number: Cay17932-10
Docosahexaenoic acid (DHA) is a long-chain omega-3 polyunsaturated fatty acid (PUFA) found in fish and algal oils. It comprises approximately 40% of total brain PUFAs and is abundant in grey matter and retinal membranes. DHA typically represents 0.52-7.5% of human total plasma fatty acids. It is produced from...
| Keywords: | 4,7,10,13,16,19-Docosahexaenoic Acid, C22:6 n-3, C22:6(4Z,7Z,10Z,13Z,16Z,19Z), Cervonic Acid, DHA,... |
| Application: | Long-chain omega-3 PUFA |
| CAS | 6217-54-5 |
| MW: | 328.5 D |
From 40.00€
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