Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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1-Oleoyl-2-hydroxy-sn-glycero-3-PA (sodium salt)
1-Oleoyl-2-hydroxy-sn-glycero-3-PA (sodium salt)

Item number: Cay62215-1

1-Oleoyl-2-hydroxy-sn-glycero-3-PA is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of PLD or through a two step process involving liberation of DAG by PLC followed by phosphorylation of DAG by diglycerol kinase....
Keywords: Oleoyl-sn-3-glycerophosphate, 9Z-octadecenoic acid, (2R)-2-hydroxy-3-(phosphonooxy)propyl ester, monosodium salt
Application: Bioactive lipid assays
CAS 325465-93-8
MW: 458.5 D
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(±)12(13)-DiHOME
(±)12(13)-DiHOME

Item number: Cay10009832-100

(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME (Cay-52450), a cytochrome P450-derived epoxide of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) also known as isoleukotoxin. It is formed from 12(13)-EpOME by soluble epoxide hydrolase (sEH) in neutrophils. 12(13)-DiHOME is toxic to Sf21 cells expressing sEH...
Keywords: Isoleukotoxin diol, 12,13-dihydroxy-9Z-octadecenoic acid
Application: Bioactive lipid assays
CAS 263399-35-5
MW: 314.5 D
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alpha-Linolenic Acid
alpha-Linolenic Acid

Item number: Cay90210-50

alpha-Linolenic acid (ALA) is an essential omega-3 polyunsaturated fatty acid found in plants. It is converted to the longer-chain fatty acids eicosapentaenoic (Cay-90110, Cay-90110.1, Cay-21908), docosapentaenoic (Cay-90165, Cay-21907), and docosahexaenoic acid (Cay-90310). It is also catabolized via fatty acid...
Keywords: ALA, C18:3 (9Z,12Z,15Z), C18:3 n-3, 9Z,12Z,15Z-octadecatrienoic acid
Application: Bioactive lipid studies
CAS 463-40-1
MW: 278.4 D
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12(S)-HETE-d8
12(S)-HETE-d8

Item number: Cay334570-25

12(S)-HETE-d8 is intended for use as an internal standard for the quantification of 12-HETE by GC- or LC-MS. (±)12-HETE is formed via non-enzymatic oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). 12(S)- and 12(R)-HETE are formed by 12(S)- and 12(R)-lipoxygenase-mediated oxidation of arachidonic...
Keywords: 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid
Application: Standard
CAS 84807-90-9
MW: 328.5 D
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Arachidonic Acid (peroxide free)
Arachidonic Acid (peroxide free)

Item number: Cay90010.1-100

Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient,...
Keywords: AA (peroxide free), 5Z,8Z,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 506-32-1
MW: 304.5 D
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12(S)-HETE
12(S)-HETE

Item number: Cay34570-25

12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.Formal Name: 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid. CAS Number: 54397-83-0. Synonyms: 12(S)-Hydroxyeicosatetraenoic Acid....
Keywords: 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 54397-83-0
MW: 320.5 D
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Dihomo-gamma-Linolenic Acid
Dihomo-gamma-Linolenic Acid

Item number: Cay90230-10

Dihomo-gamma-Linolenic Acid (DGLA, 20:3), an elongation product of gamma-linolenic acid (18:3), is rapidly metabolized by fatty acid desaturases to produce arachidonic acid (20:4). DGLA is metabolized through the cyclooxygenase pathway to produce 1-series prostaglandins, including PGE1. In mice, DGLA supplementation...
Keywords: cis-8,11,14-Eicosatrienoic Acid, DGLA, gamma-Homolinolenic Acid, 8Z,11Z,14Z-eicosatrienoic acid
Application: LTB4 receptor antagonist
CAS 1783-84-2
MW: 306.5 D
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Maresin 1
Maresin 1

Item number: Cay10878-10

Maresin 1 is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids. It is produced from docosahexaenoic acid (DHA, Cay-90310, Cay-17950) in human peripheral blood mononuclear cells (PBMCs). Maresin 1 (100 nM) reduces TNF-alpha-induced increases in reactive oxygen species (ROS) in...
Keywords: 7(R)-MaR1, 7(R)-Maresin 1, 7R,14S-dihydroxy-4Z,8E,10E,12Z,16Z,19Z-docosahexaenoic acid
Application: Inflammation studies
CAS 1268720-28-0
MW: 360.5 D
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Palmitic Acid
Palmitic Acid

Item number: Cay10006627-10

Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively. Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid...
Keywords: C16:0, hexadecanoic acid
Application: Bioactive lipid assays
CAS 57-10-3
MW: 256.4 D
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(±)19(20)-EpDPA
(±)19(20)-EpDPA

Item number: Cay10175-500

(±)-19(20)-EpDPA is an epoxide metabolite of docosahexaenoic acid (DHA, Cay-90310, Cay-17950). It is formed from DHA by various cytochrome P450 (CYP) isoforms. In vivo, (±)-19(20)-EpDPA (100 ng/animal, i.p.) suppresses hepatic crown-like structure (hCLS) formation and liver fibrosis in wild-type, but not...
Keywords: (±)19,20 EDP, (±)19,20-EpDPE, (±)19,20-epoxy Docosapentaenoic Acid, (±)19,20-epoxy DPA,...
Application: CYP450 metabolism studies
MW: 344.5 D
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12-oxo Phytodienoic Acid
12-oxo Phytodienoic Acid

Item number: Cay88520-1

12-oxo Phytodienoic acid (OPDA) is a biologically active, immediate precursor of 7-epi jasmonic acid. In addition to its link with jasmonic acid activity, OPDA appears to play an independent role in mediating resistance to pathogens and pests. As an endogenous signal transducer, OPDA has been shown to increase...
Keywords: 12-oxo PDA, OPDA, 4-oxo-5alpha-2Z-pentenyl)-2-cyclopentene-1alpha-octanoic acid
Application: Bioactive lipid assays
CAS 85551-10-6
MW: 292.4 D
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Leukotriene D4
Leukotriene D4

Item number: Cay20310-25

Leukotriene D4 (LTD4) is an active metabolite of LTC4 (Cay-20210) and a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is formed via metabolism of LTC4 by gamma-glutamyl transpeptidase. Like LTC4, LTD4 (0.01-0.1 pM) induces contractions in isolated guinea pig parenchymal strips and tracheal...
Keywords: LTD4, 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 73836-78-9
MW: 496.7 D
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