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CP-LC-1428
Item number: Cay41924-10
Lipid CP-LC-1428 is an ionizable cationic amino lipid derived from homocysteine, a naturally occurring amino acid. This lipid has demonstrated an efficient delivery and high protein expression of different kinds of RNA (mRNA, cRNA and saRNA) in vivo. Moreover, using a typical LNP formulation (IL/Ch/DOPE/PEG:...
| Keywords: | 6-methylheptyl... |
| Application: | Ionizable cationic amino lipid, homocysteine derivative |
| MW: | 1004.58 D |
From 229.00€
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Lipid 12T-O14
Item number: Cay41946-1
An amidine-incorporated degradable lipid (pKa 8.15), has been used in the generation of LNPs for the delivery of siRNA and mRNA in vitro or in vivo, LNPs containing lipid 12T-O14 and encapsulating GFP-targeting siRNA reduce GFP levels in HepG2-GFP cells, intramuscular delivery of LNPs containing lipid 12T-O14 and...
| Keywords: | tetradecyl 3-((4-((4-decylphenyl)amino)-4-iminobutyl)thio)propanoate |
| Application: | Amidine-incorporated degradable lipid, LNP formation |
| MW: | 603 D |
From 116.00€
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N-Lithocholyl-L-Alanine
Item number: Cay40929-100
A bile acid conjugate and an EPHA2 inhibitor (IC50 = 19.95 µM). Formulation: A solid. InChI: InChI=1S/C27H45NO4/c1-16(5-10-24(30)28-17(2)25(31)32)21-8-9-22-20-7-6-18-15-19(29)11-13-26(18,3)23(20)12-14-27(21,22)4/h16-23,29H,5-15H2,1-4H3,(H,28,30)(H,31,32)/t16-,17+,18-,19-,20+,21-,22+,23+,26+,27-/m1/s1. InChIKey:...
| Keywords: | N-[(3a,5beta)-3-hydroxy-24-oxocholan-24-yl]-L-alanine |
| Application: | Bile acid conjugate, EPHA2 inhibitor |
| CAS | 1428095-28-6 |
| MW: | 447.65 D |
From 110.00€
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DMT7
Item number: Cay41389-1
An ionizable cationic lipid (pKa = 6.5), has been used in the generation of LNPs for the delivery of mRNA and anticancer agents in vivo, LNPs containing DMT7 and encapsulating mRNA encoding Il-12 and MSA-2 decrease tumor volume, lung metastatic nodule numbers, and lung levels of CD4+ and CD8+ T cells in a 4T1 breast...
| Keywords: | 1-(2-(dimethylamino)ethyl)-3-((6Z,9Z,28Z,31Z)-heptatriaconta-6,9,28,31-tetraen-19-yl)thiourea |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 658.2 D |
From 105.00€
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Lipid A
Item number: Cay41708-1
An ionizable cationic lipid (pKa = 4.67). Formulation: A solution in ethanol. InChI: InChI=1S/C48H95NO5/c1-6-11-15-19-21-29-37-44(35-27-17-13-8-3)47(51)53-41-33-25-23-31-39-49(46(10-5)43-50)40-32-24-26-34-42-54-48(52)45(36-28-18-14-9-4)38-30-22-20-16-12-7-2/h44-46,50H,6-43H2,1-5H3. InChIKey:...
| Keywords: | 2-hexyl-decanoic acid, 1,1'-[[[1-(hydroxymethyl)propyl]imino]di-6,1-hexanediyl] ester |
| Application: | Ionizable cationic lipid |
| CAS | 2036273-20-6 |
| MW: | 766.27 D |
From 120.00€
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9,11-methane-epoxy Prostaglandin F1alpha
Item number: Cay10007850-100
A derivative of PGH1, induces aggregation of isolated rabbit platelet (EC50 = 0.88 µM) and contraction of rabbit aortic strips (EC50 = 0.11 µM), induces contraction of isolated guinea pig tracheas (EC50 = 3.4 µM). Formulation: A solution in methyl acetate. InChI:...
| Keywords: | 9,11-epoxymethano PGH1, 9,11-methane-epoxy PGF1alpha,... |
| Application: | Bioactive lipid assays |
| CAS | 72517-81-8 |
| MW: | 352.5 D |
From 116.00€
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O12-D3-I3
Item number: Cay41385-1
An ionizable cationic lipid (pKa = 6.39), has been used in the generation of LNPs for siRNA delivery in vitro and in vivo, LNPs containing O12-D3-I3 and encapsulating ferrocene and siRNA targeting Nrf2 or system xc- cystine/glutamate transporter decrease viability of HepG2 cells, LNPs containing O12-D3-I3 and an...
| Keywords: | didodecyl 3,3'-((3-(2-amino-3-(1H-imidazol-4-yl)propanamido)propyl)azanediyl)dipropionate |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 692.03 D |
From 60.00€
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DSPE-PEG(2000)-Biotin
Item number: Cay41914-10
A PEGylated and biotinylated form of DPSE, has been used in the generation of liposomes for the delivery of small molecules in vitro and in vivo, has been used in the formation of micelles as a precursor to immobilized liposomes for biolayer interferometry binding assays, liposomes containing DSPE-PEG(2000)-biotin...
| Keywords: | 1,2-Distearoyl-sn-glycero-3-PE-Polyethylene Glycol-2000-Biotin,... |
| Application: | PEGylated / biotinylated DPSE |
From 151.00€
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C8 Ceramide-mPEG(2000)
Item number: Cay41954-1
A PEGylated form of C8 ceramide, has been used in the generation of lipoplexes and lipid particles for the delivery of plasmid DNA and siRNA in vitro and in vivo, lipid particles encapsulating plasmid DNA and containing C8 MPEG(2000) ceramide have a higher transfection efficiency than those containing C14- or C20...
| Keywords: | Capryl Ceramide Methoxy Polyethylene Glycol-2000, N-Capryl-D-erythro-Sphingosine mPEG(2000),... |
| Application: | PEGylated C8 ceramide |
| CAS | 212116-76-2 |
From 411.00€
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C16 Ceramide-mPEG(2000)
Item number: Cay41955-1
A PEGylated form of C16 ceramide, has been used in the generation of microspheres, LNPs, and liposomes for the delivery of small molecules, mRNA, and plasmid DNA in vitro and in vivo, liposomes containing C16 ceramide-mPEG(2000) with a stearylated-INF7 and have been used to transfect plasmid DNA into MFLM-4 cells,...
| Keywords: | Cer(d18:1/16:0) MPEG(2000), MPEG(2000) Ceramide (d18:1/16:0), N-Hexadecanoyl-D-erythro-Sphingosine mPEG(2000),... |
| Application: | PEGylated C16 ceramide PEGylated form |
| CAS | 212116-78-4 |
From 74.00€
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