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Hyocholic Acid
Item number: Cay20293-1
Hyocholic acid is a primary bile acid in pigs and other mammals. It has also been found in urine samples from patients with cholestasis. Hyocholic acid is converted by gut microflora primarily to taurohyocholate and, to a lesser extent, taurocholic acid (Cay-16215) and tauro-beta-muricholic acid (Cay-20289) in mice....
| Keywords: | HCA, gamma-MCA, gamma-Muricholic Acid, (5beta)-3alpha,6alpha,7alpha-trihydroxy-cholan-24-oic acid |
| Application: | Bile acid |
| CAS | 547-75-1 |
| MW: | 408.6 D |
From 49.00€
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Prostaglandin E2 MaxSpec(R) Standard
Item number: Cay10007211-100
Prostaglandin E2 (PGE2) is one of the primary COX products of arachidonic acid (Cay-90010) and one of the most widely investigated PGs. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct...
| Keywords: | Dinoprostone, PGE2, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 363-24-6 |
| MW: | 352.5 D |
93.00€
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Myristic Acid
Item number: Cay13351-1
Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.Formal Name:...
| Keywords: | C14:0, NSC 5028, tetradecanoic acid |
| Application: | N-myristoylation |
| CAS | 544-63-8 |
| MW: | 228.4 D |
From 23.00€
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7-keto Cholesterol
Item number: Cay16339-5
7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL. It is produced by oxidation of cholesterol via ethanol-mediated lipid peroxidation or photodamage as well as oxidation of 7-dehydro cholesterol (Cay-14612) by the cytochrome P450 (CYP) isoform CYP7A1. 7-keto Cholesterol...
| Keywords: | 7-oxo Cholesterol, SC-4722, Delta5-Cholesterol-3beta-ol-7-one, 3beta-hydroxy-cholest-5-en-7-one |
| Application: | Bioactive sterol, CYP7A1 inhibitor |
| CAS | 566-28-9 |
| MW: | 400.6 D |
From 85.00€
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Hydrocortisone 21-hemisuccinate (sodium salt)
Item number: Cay18226-100
Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. It can bind to glucocorticoid receptors, initiating the transcription of anti-inflammatory and immunosuppressive mediators and inhibiting proinflammatory cytokine activity (IC50 = 6.7 µM for IL-6). It is commonly used to...
| Keywords: | Cortisol 21-hemisuccinate, Hydrocortisone sodium succinate, ST51037292, U-4905,... |
| Application: | Water-soluble cortisol derivative, GR ligand, pluripotent stem cell differentiation |
| CAS | 125-04-2 |
| MW: | 484.5 D |
From 53.00€
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U-75302
Item number: Cay70705-100
U-75302 is an LTB4 receptor antagonist with a Ki of 159 nM on guinea pig lung membranes. This activity is specific for the BLT1 receptor, U-75302 does not antagonize the binding of [3H]-LTB4 to the human BLT2 receptor.Formal Name: 6-(6-(3R-hydroxy-1E,5Z-undecadien-1-yl)-2-pyridinyl)-1,5S-hexanediol. CAS Number:...
| Keywords: | 6-(6-(3R-hydroxy-1E,5Z-undecadien-1-yl)-2-pyridinyl)-1,5S-hexanediol |
| Application: | LTB4 receptor antagonist |
| CAS | 119477-85-9 |
| MW: | 361.5 D |
From 130.00€
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MS-PPOH
Item number: Cay75770-10
Arachidonic acid is converted by microsomal CYP450 enzymes to a variety of epoxides, omega-1 and omega-hydroxylated compounds via what is known as the epoxidase pathway. MS-PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes. MS-PPOH inhibits the formation of...
| Keywords: | N-(methylsulfonyl)-2-(2-propynyloxy)-benzenehexanamide |
| Application: | Epoxygenation inhibitor |
| CAS | 206052-02-0 |
| MW: | 323.4 D |
From 36.00€
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Adrenic Acid
Item number: Cay90300-10
Adrenic acid is a naturally occurring polyunsaturated fatty acid (PUFA) formed through a 2-carbon chain elongation of arachidonic acid. It is present in the adrenal glands, brain, testis, and kidney. Although there is trace metabolism of adrenic acid in the forebrain, the renal medulla is the only tissue which...
| Keywords: | Adrenic Acid, 7Z,10Z,13Z,16Z-docosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 28874-58-0 |
| MW: | 332.5 D |
From 58.00€
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11(Z)-Eicosenoic Acid
Item number: Cay20606-100
11(Z)-Eicosenoic acid is one of several monounsaturated 20-carbon fatty acids. The combined C20:1 isomers constitute 70% of the total fatty acid pool in jojoba seed oil isolated from plants in the Arizona desert.Formal Name: 11Z-eicosenoic acid. CAS Number: 5561-99-9. Synonyms: cis-11-Eicosenoic Acid, FA 20:1....
| Keywords: | cis-11-Eicosenoic Acid, 11Z-eicosenoic acid |
| CAS | 5561-99-9 |
| MW: | 310.5 D |
From 102.00€
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Palmitelaidic Acid
Item number: Cay9001798-100
Palmitelaidic acid is a trans isomer of palmitoleic acid (Cay-10009871, Cay-21911) and dietary fatty acid that has been found in dairy fat products and various partially hydrogenated oils. It decreases nitric oxide (NO) production and levels of soluble E-selectin in isolated human aortic endothelial cells (HAECs)...
| Keywords: | 9-trans-Hexadecenoic Acid, C16:1(9E), (9E)-hexadecenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 10030-73-6 |
| MW: | 254.4 D |
From 68.00€
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Protectin D1
Item number: Cay10010390-10
Protectin D1 is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid (DHA, Cay-90310). DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to protectin D1 enzymatically. Protectin D1 increases phagocytosis of apoptotic polymorphonuclear leukocytes (PMNs) by macrophages in a...
| Keywords: | Neuroprotectin D1, Neuroprotectin D1/Protectin D1, NPD1, PD1, 10R,17S-dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid |
| Application: | Specialized pro-resolving mediator (SPM) |
| CAS | 660430-03-5 |
| MW: | 360.5 D |
From 192.00€
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Arachidonic Acid MaxSpec(R) Standard
Item number: Cay10007268-1
Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient,...
| Keywords: | AA, 5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Quantitative MS standard |
| CAS | 506-32-1 |
| MW: | 304.5 D |
97.00€
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