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10-oxo-12(Z)-Octadecenoic Acid
Item number: Cay36977-1
10-oxo-12(Z)-Octadecenoic acid is a metabolite of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) and an activator of transient receptor potential vanilloid 1 (TRPV1). It is formed from linoleic acid by conjugated linoleic acid dehydrogenase (CLA-DH) via a 10-hydroxy-12(Z)-octadecenoic acid intermediate and can...
| Keywords: | 10-keto-12Z-Octadecenoic Acid, 10-oxo-12-cis-Octadecenoic Acid |
| Application: | Linoleic acid metabolite, TRPV1 activator |
| CAS | 103521-29-5 |
| MW: | 296.5 D |
From 173.00€
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10-oxo-12(Z)-Octadecenoic Acid-d5
Item number: Cay36986-100
10-oxo-12(Z)-Octadecenoic acid-d5 is intended for use as an internal standard for the quantification of 10-oxo-12(Z)-octadecenoic acid (Cay-36977) by GC- or LC-MS. 10-oxo-12(Z)-Octadecenoic acid is a metabolite of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) and an activator of transient receptor potential...
| Keywords: | 10-keto-12Z-Octadecenoic Acid-d5, 10-oxo-12-cis-Octadecenoic Acid-d5, (Z)-10-oxooctadec-12-enoic-17,17,18,18,18-d5 acid |
| Application: | GC-MS, LC-MS internal standard, quantification, linoleic acid metabolite |
| MW: | 301.5 D |
From 269.00€
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TCL053
Item number: Cay37045-10
TCL053 is an ionizable cationic amino lipid. It has been used in the generation of lipid nanoparticles (LNPs) and has a pKa value of 6.8. LNPs containing TCL053 and encapsulating mRNA encoding the Cas9 nuclease, in combination with LNPs containing TCL053 and encapsulating single-guide RNA (sgRNA) targeting the...
| Keywords: | 2-(((4-(dimethylamino)butanoyl)oxy)methyl)-2-((((Z)-tetradec-9-enoyl)oxy)methyl)propane-1,3-diyl... |
| Application: | Ionizable amino lipid |
| CAS | 2361162-70-9 |
| MW: | 874.3 D |
From 180.00€
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5-Aminosalicylic Acid-d7
Item number: Cay37197-1
5-Aminosalicylic acid-d7 (5-ASA-d7) is intended for use as an internal standard for the quantification of 5-ASA (Cay-70265) by GC- or LC-MS. 5-ASA is a non-steroidal anti-inflammatory drug (NSAID) and an active metabolite of sulphasalazine (Cay-15025), basalazide (Cay-18680), and olsalazine (Cay-23661). It...
| Keywords: | 5-ASA-d7, Mesalamine-d7, Mesalazine-d7, 5-(amino-d2)-2-(hydroxy-d)benzoic-d3 acid-d |
| Application: | GC-MS, LC-MS, internal standard, quantification, COX inhibitor |
| MW: | 160.2 D |
From 166.00€
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(±)-10-hydroxy-12(Z)-Octadecenoic Acid
Item number: Cay37281-1
(±)-10-hydroxy-12(Z)-Octadecenoic acid is a racemic mixture of 10(R)-hydroxy-12(Z)-octadecenoic acid and 10(S)-hydroxy-12(Z)-octadecenoic acid. 10(S)-hydroxy-12(Z)-Octadecenoic acid, also known as HYA(TM), is a gut microbiome metabolite of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) that is formed by...
| Keywords: | 10-hydroxy-cis-12-Octadecenoic Acid, 10-hydroxy-12Z-octadecenoic acid |
| Application: | Oxylipin, linoleic acid metabolite |
| CAS | 34932-12-2 |
| MW: | 298.5 D |
From 47.00€
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(±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5
Item number: Cay37282-100
(±)-10-hydroxy-12(Z)-Octadecenoic acid-d5 is intended for use as an internal standard for the quantification of (±)-10-hydroxy-12(Z)-octadecenoic acid (Cay-37281) by GC- or LC-MS. (±)-10-hydroxy-12(Z)-Octadecenoic acid is an oxylipin and a metabolite of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909). It is formed...
| Keywords: | 10-hydroxy-cis-12-Octadecenoic Acid-d5, 10-hydroxyoctadec-12Z-enoic-17,17,18,18,18-d5 acid |
| Application: | GC-MS, LC-MS, internal standard, quantification, oxylipin, linoleic acid metabolite |
| MW: | 303.5 D |
From 243.00€
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PGS-IN-1
Item number: Cay37666-1
PGS-IN-1 is a non-steroidal anti-inflammatory drug (NSAID) and a dual inhibitor of COX and 5-lipoxygenase (5-LO, IC50s = 0.44 and 0.85 µM, respectively). It is selective for 5-LO over 12-LO (IC50 = >100 µM for the rabbit enzyme ). Oral administration of PGS-IN-1 (10 mg/kg per day) inhibits paw swelling and bone...
| Keywords: | KME-4, PG Synthetase Inhibitor 1, PGS Inhibitor 1, Prostaglandin Synthetase Inhibitor 1,... |
| Application: | NSAID, COX / 5-LO dual inhibitor |
| CAS | 102271-49-8 |
| MW: | 302.4 D |
From 42.00€
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OF-Deg-Lin
Item number: Cay37853-1
OF-Deg-Lin is an ionizable cationic lipid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro.Formal Name: 9Z,12Z-octadecadienoic acid, 1,1',1'',1'''-[(3,6-dioxo-2,5-piperazinediyl)bis(4,1-butanediylnitrilodi-2,1-ethanediyl)] ester. CAS Number: 1853202-95-5. Molecular...
| Keywords: | 9Z,12Z-octadecadienoic acid, 1,1',1'',1'''-[(3,6-dioxo-2,5-piperazinediyl)bis(4,1-butanediylnitrilodi-2,1-ethanediyl)] ester |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 1853202-95-5 |
| MW: | 1482.3 D |
From 115.00€
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Arachidonic Acid-d11 ethyl ester
Item number: Cay37970-100
Arachidonic acid-d11 ethyl ester is intended for use as an internal standard for the quantification of arachidonic acid ethyl ester (Cay-10008200) by GC- or LC-MS. Arachidonic acid ethyl ester is an esterified form of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It is commonly used as a source of...
| Keywords: | C20:4 (cis-5,8,11,14)-d11 ethyl ester, Ethyl (cis-5,8,11,14)-eicosatetraenoate-d11, Ethyl Arachidonate-d11,... |
| Application: | GC-MS, LC-MS internal standard, quantification, arachidonic acid ethyl ester |
| MW: | 343.6 D |
From 174.00€
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Docosahexaenoic Acid-d5 ethyl ester
Item number: Cay37971-100
Docosahexaenoic acid-d5 ethyl ester (DHA-d5 ethyl ester) is intended for use as an internal standard for the quantification of docosahexaenoic acid ethyl ester (Cay-9090310) by GC- or LC-MS. Docosahexaenoic acid (DHA) ethyl ester is an esterified form of the omega-3 fatty acid DHA (Cay-90310, Cay-17950). DHA ethyl...
| Keywords: | 4,7,10,13,16,19-Docosahexaenoic Acid-d5 ethyl ester, C22:6 n-3-d5 ethyl ester, C22:6(4Z,7Z,10Z,13Z,16Z,19Z)-d5 ethyl... |
| Application: | GC-MS, LC-MS internal standard, quantification, omega-3 PUFA ester |
| CAS | 159146-01-7 |
| MW: | 361.6 D |
From 174.00€
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CAY10795
Item number: Cay37981-1
CAY10795 is a 15-hydroxy prostaglandin dehydrogenase (15-PGDH) inhibitor (IC50 = 3 nM). It increases prostaglandin E2 (PGE2, Cay-14010) levels greater than 3-fold in IL-1beta-stimulated A549 human lung cells when used at a concentration of 500 nM. CAY10795 reduces 15-PGDH activity in the colon of mice when...
| Keywords: | 15-hydroxy Prostaglandin Dehydrogenase Inhibitor, 15-PGDH Inhibitor,... |
| Application: | 15-PGDH inhibitor |
| CAS | 2241676-74-2 |
| MW: | 398.5 D |
From 104.00€
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Ethyl HDFP
Item number: Cay38209-1
Ethyl HDFP is a lipase inhibitor. It inhibits 12 lipases, including fatty acid amide hydrolase (FAAH), fatty acid synthase (FASN), and alpha/beta-hydrolase domain-containing protein 4 (ABHD4), by greater than 75% in mouse T cell hybridoma lysates when used at a concentration of 2 µM. Ethyl HDFP inhibits...
| Keywords: | Ethyl P-Hexadecylphosphonofluoridate, Ethyl Hexadecylfluorophosphonate, p-hexadecyl-phosphonofluoridic acid, ethyl ester |
| Application: | Lipase inhibitor |
| CAS | 1407160-81-9 |
| MW: | 336.5 D |
From 57.00€
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