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YSK05
Item number: Cay35786-10
YSK05 is an ionizable cationic amino lipid (apparent pKa = ~6.5) that has been used in combination with other lipids in the formation of liposomes and lipid nanoparticles (LNPs). Administration of cyclic di-GMP (Cay-17144) in YSK05-containing liposomes increases serum levels of IFN-beta, IFN-gamma, IL-6, and...
| Keywords: | 1-methyl-4,4-bis[(9Z,12Z)-9,12-octadecadien-1-yloxy]-piperidine |
| Application: | Ionizable amino lipid, LNP formation |
| CAS | 1318793-78-0 |
| MW: | 628.1 D |
From 122.00€
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N-acetyl-2-Aminophenol
Item number: Cay35829-100
N-acetyl-2-Aminophenol is a derivative of the analgesic and antipyretic acetaminophen (Cay-10024) that has been found in P. fluorescens. It inhibits platelet aggregation induced by ADP (Cay-16778, Cay-21121) or arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) in isolated human platelet-rich plasma when used...
| Keywords: | 2-Acetamidophenol, 2-Acetaminophenol, AAP, N-acetyl-o-Aminophenol, N-acetyl-ortho-Aminophenol, NSC 3989, Orthocetamol,... |
| Application: | Acetaminophen derivative |
| CAS | 614-80-2 |
| MW: | 151.2 D |
From 42.00€
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Metapristone
Item number: Cay36380-1
Metapristone is an active metabolite of the glucocorticoid, progesterone, and androgen receptor antagonist mifepristone (Cay-10006317). It is formed from mifepristone by the cytochrome P450 (CYP) isoform CYP3A4. Metapristone is an antagonist of human glucocorticoid and progesterone receptors with relative affinities...
| Keywords: | N-desmethyl Mifepristone, N-desmethyl RU-486, RU-42633,... |
| Application: | Abortifacient mifepristone active metabolite |
| CAS | 104004-96-8 |
| MW: | 415.6 D |
From 119.00€
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1,2-Dioleoyl-sn-glycero-3-EPC (chloride)
Item number: Cay36473-10
1,2-Dioleoyl-sn-glycero-3-EPC is a cationic esterized phospholipid. It has been used in combination with other lipids in the formation of lipid bilayers.Formal Name: 4-ethoxy-N,N,N-trimethyl-10-oxo-7R-[[(9Z)-1-oxo-9-octadecenyl] oxy]-3,5,9-trioxa-4-phosphaheptacos-18Z-en-1-aminium 4-oxide, monochloride. CAS Number:...
| Keywords: | 1,2-Dioleoyl-sn-glycero-3-Ethylphosphocholine, 18:1-EPC, 4-ethoxy-N,N,N-trimethyl-10-oxo-7R-[[(9Z)-1-oxo-9-octadecenyl]... |
| Application: | Cationic esterized phospholipid, lipid bilayer formation |
| CAS | 474945-24-9 |
| MW: | 850.6 D |
From 80.00€
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DLin-DMA
Item number: Cay36701-10
DLin-DMA is an ionizable cationic amino lipid (pKa = 6.7) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of nucleic acids.Formal Name: N,N-dimethyl-2,3-bis[(9Z,12Z)-9,12-octadecadien-1-yloxy]-1-propanamine. CAS Number: 871258-12-7. Synonyms:...
| Keywords: | 1,2-Dilinoleyloxy-N,N-dimethyl-3-aminopropane, N,N-dimethyl-2,3-bis[(9Z,12Z)-9,12-octadecadien-1-yloxy]-1-propanamine |
| Application: | Ionizable amino lipid |
| CAS | 871258-12-7 |
| MW: | 616.1 D |
From 70.00€
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1-Oleoyl-2-Lauroyl-3-Palmitoyl-rac-glycerol
Item number: Cay36859-1
1-Oleoyl-2-lauroyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains oleic acid (Cay-90260, Cay-24659), lauric acid (Cay-10006626), and palmitic acid (Cay-10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in a variety of plant oils, including walnut, almond, poppy seed, and...
| Keywords: | 1-Olein-2-Laurin-3-Palmitin, TG(18:1/12:0/16:0), (9Z)-octadecenoic acid,... |
| Application: | Triacylglycerol |
| CAS | 1183882-29-2 |
| MW: | 777.3 D |
From 101.00€
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10-oxo-12(Z),15(Z)-Octadecadienoic Acid
Item number: Cay36976-100
10-oxo-12(Z),15(Z)-Octadecadienoic acid is an oxylipin. It is produced from alpha-linolenic acid (Cay-90210, Cay-21910) by the gut bacteria L. plantarum. Octadecadienoic acid reduces the increase in mRNA expression levels of the gene encoding SREBP-1c induced by the liver X receptor agonist T0901317 (Cay-71810) in...
| Keywords: | 10-oxo-12(Z),15(Z)-18:2, 10-oxo-12(Z),15(Z)-ODE, 10-oxo-12Z,15Z-octadecadienoic acid |
| Application: | Oxylipin gut microbiota metabolite |
| CAS | 1036406-73-1 |
| MW: | 294.4 D |
From 144.00€
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306-O12B-3
Item number: Cay37096-10
306-O12B-3 is an ionizable cationic lipidoid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of antisense oligonucleotides (ASOs). LNPs containing 306-O12B-3 localize to the liver after intravenous administration in mice. LNPs containing 306-O12B-3 in combination with other lipids...
| Keywords: | bis(2-(octyldisulfaneyl)ethyl) 3,3'-((4-methyl-11-oxo-12-oxa-15,16-dithia-4,8-diazatetracosyl)azanediyl)dipropionate |
| Application: | Cationic lipidoid, LNP formation, antisense oligonucleotide delivery |
| MW: | 974.6 D |
From 193.00€
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Cho-es-Lys
Item number: Cay37337-1
Cho-es-Lys is a cationic cholesterol derivative composed of cholesterol (Cay-9003100) conjugated to an L-lysine head group containing two primary amines (pKas = 10.48 and 9.46) via a hexanediol linker. It has been used for transfection of Cy3-pDNA in COS-7 cells. Cho-es-Lys nanocomplexes containing luciferase siRNA...
| Keywords: | CEL, L-lysine, 6-[[[(3beta)-cholest-5-en-3-yloxy]carbonyl]oxy]hexyl ester, 2,2,2-trifluoroacetate |
| Application: | Cationic cholesterol derivative w/two primary amines |
| CAS | 1356250-80-0 |
| MW: | 887.1 D |
From 47.00€
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24alpha-ethyl Cholesterol
Item number: Cay37386-10
24alpha-ethyl Cholesterol is a phytosterol that has been found in S. plebian and has diverse biological activities. It protects lard from thermal oxidation when used at concentrations of 0.02 and 0.04%. 24alpha-ethyl Cholesterol (100 µM) induces glucose uptake and lipolysis in primary rat differentiated adipocytes...
| Keywords: | beta-Sitosterol, 22,23-dihydro Stigmasterol, Cupreol, NSC 18173, NSC 49083, NSC 8096, Rhamnol, SKF 14463,... |
| Application: | Bioactive phytosterol |
| CAS | 83-46-5 |
| MW: | 414.7 D |
From 147.00€
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Ermanin
Item number: Cay37535-10
Ermanin is a methoxylated flavone that has been found in bee glue and has diverse biological activities. It increases the levels of intracellular reactive oxygen species (ROS) and decreases the levels of glutathione (GSH) in B16/F10 mouse melanoma cells and primary mouse melanocytes when used at concentrations of 8...
| Keywords: | 5,7-Dihydroxy-3,4'-dimethoxyflavone, Kaempferol 3,4'-di-O-methyl ether, NSC 31882,... |
| Application: | Bioactive methoxylated flavone |
| CAS | 20869-95-8 |
| MW: | 314.3 D |
From 57.00€
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306-O12B
Item number: Cay37549-10
306-O12B is an ionizable cationic lipidoid. It has been used in the generation of lipid nanoparticles (LNPs). Intravenous administration of LNPs containing 306-O12B and encapsulating an mRNA reporter accumulate specifically in the mouse liver. LNPs containing 306-O12B and encapsulating mRNA encoding the Cas9...
| Keywords: | tetrakis(2-(octyldisulfaneyl)ethyl) 3,3',3'',3'''-(((methylazanediyl)bis(propane-3,1-diyl))bis(azanetriyl))tetrapropionate |
| Application: | Ionizable cationic lipidoid, LNP formation |
| CAS | 2566523-06-4 |
| MW: | 1251.09 D |
From 162.00€
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