Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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Solanidine
Solanidine

Item number: Cay36433-1

Solanidine is a steroidal glycoalkaloid metabolite that has been found in potato (S. tuberosum) and has anticancer and teratogenic activities. It inhibits the growth of HT-29 colon and HepG2 liver cancer cells by 80.9 and 82.2%, respectively, when used at a concentration of 100 µg/ml. Solanidine (176 mg/kg) is...
Keywords: (-)-Solanidine, 22R,25S-Solanidine, NSC 76025, (3beta)-solanid-5-en-3-ol
Application: Steroidal glycoalkaloid metabolite, anticancer / teratogenic agent
CAS 80-78-4
MW: 397.6 D
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Anecortave Acetate
Anecortave Acetate

Item number: Cay36441-100

Anecortave acetate is a sterol lipid. It inhibits VEGF-induced increases in vascular generation, number, and length in isolated rat retinas when used at a concentration of 1 µM. Sub-tenon administration of anecortave acetate (7.5% w/v) prevents and reduces increases in intraocular pressure induced by prednisolone...
Keywords: AL 3789, NSC 15475, NSC 24345, 21-(acetyloxy)-17-hydroxy-pregna-4,9(11)-diene-3,20-dione
Application: Sterol lipid
CAS 7753-60-8
MW: 386.5 D
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3-Methyladipic Acid
3-Methyladipic Acid

Item number: Cay36452-10

3-Methyladipic acid is a catabolite of the branched-chain fatty acid phytanic acid (Cay-90360), which is ingested via the diet. It is formed from phytanic acid via omega- and then beta-oxidation in patients with adult Refsum disease, a disorder characterized by high levels of phytanic acid in the blood and tissues...
Keywords: NSC 22069, 3-methyl-hexanedioic acid
Application: Phytanic acid catabolite
CAS 3058-01-3
MW: 160.2 D
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UDP-N-acetyl-D-Galactosamine (sodium salt)
UDP-N-acetyl-D-Galactosamine (sodium salt)

Item number: Cay36506-1

UDP-N-acetyl-D-galactosamine is a nucleotide sugar that is used for glycosylation by glycosyltransferases, which transfer the N-acetyl-D-galactosamine (Cay-31728) moiety to various substrates.Formal Name: uridine 5'-(trihydrogen diphosphate), P'-[2-(acetylamino)-2-deoxy-alpha-D-galactopyranosyl] ester, disodium...
Keywords: UDP-GalNAc, Uridine 5'-diphosphate GalNAc, uridine 5'-(trihydrogen diphosphate),...
Application: Nucleotide sugar
CAS 108320-87-2
MW: 651.3 D
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4-Allylcatechol
4-Allylcatechol

Item number: Cay36542-10

4-Allylcatechol is a phenol that has been found in P. betle and has diverse biological activities. It scavenges DPPH (Cay-14805) radicals, reduces the formation of thiobarbituric acid reactive substances (TBARS), and inhibits xanthine oxidase in cell-free assays (IC50s = 20.17, 2, and 16.7 µM, respectively)....
Keywords: 1,2-Dihydroxy-4-allylbenzene, 4-Allylbenzene-1,2-diol, 4-Allylpyrocatechol, Hydroxychavicol,...
Application: Bioactive phenol
CAS 1126-61-0
MW: 150.2 D
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trans-Petroselinic Acid methyl ester
trans-Petroselinic Acid methyl ester

Item number: Cay36670-10

trans-Petroselinic acid methyl ester is a long-chain fatty acid methyl ester and esterified form of trans-petroselinic acid (Cay-20026).Formal Name: 6E-octadecenoic acid, methyl ester. CAS Number: 14620-36-1. Synonyms: Delta6-trans-Octadecenoic Acid methyl ester, trans-6-Octadecenoic Acid methyl ester, Petroselaidic...
Keywords: trans-6-Octadecenoic Acid methyl ester, Petroselaidic Acid methyl ester, Delta6-trans-Octadecenoic Acid methyl ester,...
Application: Long-chain fatty acid methyl ester
CAS 14620-36-1
MW: 296.5 D
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Asaraldehyde
Asaraldehyde

Item number: Cay36798-100

Asaraldehyde is a plant metabolite that has been found in D. carota and has diverse biological activities. It selectively inhibits COX-2 over COX-1 when used at a concentration of 100 µg/ml and inhibits aggregation of washed isolated rabbit platelet-rich plasma induced by arachidonic acid (Cay-90010, Cay-90010.1,...
Keywords: 2,4,5-Trimethoxybenzaldehyde, Asaronaldehyde, Asarylaldehyde, NSC 89299, 2,4,5-trimethoxy-benzaldehyde
Application: Bioactive plant metabolite
CAS 4460-86-0
MW: 196.2 D
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Pep2-8
Pep2-8

Item number: Cay36923-1

Pep2-8 is a peptide inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9, IC50 = 1.4 µM). It reverses PCSK9-induced decreases in surface LDL receptor levels and restores uptake of LDL in HepG2 cells in a concentration-dependent manner.Formal Name:...
Keywords: TVFTSWEEYLDWV-NH2,...
Application: PCSK9 peptide inhibitor
CAS 1541011-97-5
MW: 1715.9 D
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1-1(Z)-Octadecenyl-2-Arachidonoyl-sn-glycero-3-PC
1-1(Z)-Octadecenyl-2-Arachidonoyl-sn-glycero-3-PC

Item number: Cay37132-1

1-1(Z)-Octadecenyl-2-Arachidonoyl-sn-glycero-3-PC is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) at the sn-1 and sn-2 positions, respectively. It scavenges singlet oxygen in a cell-free assay.Formal Name:...
Keywords: 1-1(Z)-Octadecenyl-2-Arachidonoyl-sn-glycero-3-Phosphatidylcholine,...
Application: Plasmalogen
CAS 97802-56-7
MW: 794.1 D
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1-1(Z)-Octadecenyl-2-Adrenoyl-sn-glycero-3-PC
1-1(Z)-Octadecenyl-2-Adrenoyl-sn-glycero-3-PC

Item number: Cay37133-1

1-1(Z)-Octadecenyl-2-adrenoyl-sn-glycero-3-PC is a plasmalogen that contains 1(Z)-octadecenoic acid and adrenic acid (Cay-90300) at the sn-1 and sn-2 positions, respectively.Formal Name: (R)-2-(((7Z,10Z,13Z,16Z)-docosa-7,10,13,16-tetraenoyl)oxy)-3-(((Z)-octadec-1-en-1-yl)oxy)propyl (2-(trimethylammonio)ethyl)...
Keywords: 1-1(Z)-Octadecenyl-2-Adrenoyl-sn-glycero-3-Phosphatidylcholine, 1-1(Z)-Octadecenyl-2-Adrenoyl-sn-glycero-3-Phosphocholine,...
Application: Plasmalogen
MW: 822.2 D
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10-oxo-12(Z)-Octadecenoic Acid ethyl ester
10-oxo-12(Z)-Octadecenoic Acid ethyl ester

Item number: Cay37222-1

10-oxo-12(Z)-Octadecenoic acid ethyl ester is an ester form of 10-oxo-12(Z)-Octadecenoic acid (Cay-36977). It increases the expression of the gene encoding mitochondrial uncoupling protein 1 (Ucp1) in brown and white adipose tissue in a KKAy mouse model of obesity and diabetes.Synonyms: 10-keto-12Z-Octadecenoic Acid...
Keywords: 10-keto-12Z-Octadecenoic Acid ethyl ester, 10-oxo-12-cis-Octadecenoic Acid ethyl ester
Application: 10-oxo-12(Z)-octadecenoic acid, ester form
MW: 324.5 D
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DOG-IM4
DOG-IM4

Item number: Cay37441-1

DOG-IM4 is an ionizable cationic lipid (apparent pKa = 5.6) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA. Immunization with LNPs containing DOG-IM4 and encapsulating mRNA encoding influenza A hemagglutinin (HA) increases HA-inhibiting antibody titers (HI titers) in mice...
Keywords: N-[(25Z)-14-[(9Z)-9-octadecen-1-yloxy]-3,6,9,12,16-pentaoxatetratriacont-25-en-1-yl]-1H-imidazole-5-carboxamide
Application: Ionizable cationic lipid, LNP formation, mRNA delivery
CAS 2758097-38-8
MW: 862.32 D
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340 from 353 pages