Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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12-oxo-9(Z)-Dodecenoic Acid
12-oxo-9(Z)-Dodecenoic Acid

Item number: Cay37713-1

12-oxo-9(Z)-Dodecenoic acid is an omega-oxoacid and a metabolite of the omega-6 PUFA linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) and the omega-3 PUFA alpha-linolenic acid (Cay-90210, Cay-21910). It is formed from these PUFAs via lipoxygenase-produced 13-hydroperoxy intermediates by hydroperoxide lyase in...
Keywords: 12-keto-9Z-Dodecenoic Acid, 12-oxo-9-cis-Dodecenoic Acid, (9Z)-12-oxo-9-dodecenoic acid
Application: Linoleic acid / linolenic acid metabolite
CAS 60485-39-4
MW: 212.3 D
From 151.00€ *
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L202
L202

Item number: Cay37841-1

L202 is an ionizable cationic lipid (pKa = 6.04) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA. Intramuscular administration of LNPs containing L202 and encapsulating nucleoside-modified mRNA encoding pre-fusion stabilized severe acute respiratory syndrome coronavirus 2...
Keywords: 1-methyl-4-piperidinecarboxylic acid, 2-[9-oxo-9-[(3-pentyloctyl)oxy]nonyl]dodecyl ester
Application: Ionizable cationic lipid, LNP formation
CAS 2170488-92-1
MW: 650.1 D
From 169.00€ *
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246C10
246C10

Item number: Cay37907-10

246C10 is an ionizable cationic lipid (pKa = 6.75). It has been used in combination with other lipids in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. Intravenous administration of LNPs containing 246C10 and encapsulating an mRNA reporter selectively accumulate in mouse...
Keywords: 1,1',1'',1'''-[1,4-piperazinediylbis(3,1-propanediylnitrilo)]tetrakis-2-dodecanol
Application: Ionizable cationic lipid, LNP formation
CAS 2635329-26-7
MW: 937.6 D
From 151.00€ *
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Linoleic Acid-d11 ethyl ester
Linoleic Acid-d11 ethyl ester

Item number: Cay37973-100

Linoleic acid-d11 ethyl ester is intended for use as an internal standard for the quantification of linoleic acid ethyl ester (Cay-10008198) by GC- or LC-MS. Linoleic acid ethyl ester is an esterified form of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909). It is active against the bacteria S. mutans, A....
Keywords: C18:2 (cis-9,12)-d11 ethyl ester, Ethyl cis-9,12-Octadecadienoate-d11, Ethyl Linoleate-d11, Telfairic Acid-d11 ethyl...
Application: GC-MS, LC-MS internal standard, quantification, omega-6 PUFA ester
MW: 319.6 D
From 75.00€ *
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Lipid A4
Lipid A4

Item number: Cay38351-1

Lipid A4 is a branched-chain ionizable cationic lipidoid that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA. LNPs containing lipid A4 and encapsulating an mRNA reporter accumulate in the uterus, placenta, and ovaries, as well as to the spleen and liver, in pregnant mouse dams...
Keywords: 1,1'-((2-(2-(4-(2-((2-(2-(bis(2-hydroxydodecyl)amino)ethoxy)ethyl)(2-hydroxydodecyl)amino)ethyl)piperazin-1-yl)ethoxy)ethy...
Application: Branched-chain ionizable cationic lipidoid, LNP formation
CAS 2639634-71-0
MW: 1225 D
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5-(3'-Hydroxyphenyl)-gamma-Valerolactone
5-(3'-Hydroxyphenyl)-gamma-Valerolactone

Item number: Cay38519-10

5-(3'-Hydroxyphenyl)-gamma-valerolactone is a metabolite of various polyphenols, including (+)-catechin (Cay-70940) and (-)-epicatechin (Cay-11807). It is formed from these polyphenols by gut microbiota.Formal Name: dihydro-5-[(3-hydroxyphenyl)methyl]-2(3H)-furanone. CAS Number: 21618-91-7. Synonyms:...
Keywords: (3'-hydroxy)-PVL, 5-(3'-Hydroxyphenyl)-gamma-VL, delta-(3'-Hydroxyphenyl)-gamma-Valerolactone,...
Application: Various polyphenol metabolite
CAS 21618-91-7
MW: 192.2 D
From 69.00€ *
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C14-SPM
C14-SPM

Item number: Cay38785-10

C14-SPM is a polyamine branched-chain lipidoid. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of siRNA.Formal Name: 15,19,24,28-tetrakis(2-hydroxytetradecyl)-15,19,24,28-tetraazadotetracontane-13,30-diol. CAS Number: 2241864-59-3. Synonyms:...
Keywords: C14-Spermine, 15,19,24,28-tetrakis(2-hydroxytetradecyl)-15,19,24,28-tetraazadotetracontane-13,30-diol
Application: Polyamine branched-chain lipidoid, LNP formation
CAS 2241864-59-3
MW: 1476.6 D
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IR-117-17
IR-117-17

Item number: Cay40420-10

IR-117-17 is an ionizable cationic and biodegradable amino lipid. It has been used in the generation of lipid nanoparticles (LNPs). Nebulized administration of LNPs containing IR-117-17 and the cationic lipid 1,2-dioleoyl-2-trimethylammoniumpropane (1,2-DOTAP, Cay-15110), among other components, and encapsulating...
Keywords: A10-LIN, 5-(((3-(dibutylamino)propyl)amino)methyl)-6-hydroxyundecane-1,11-diyl (9Z,9'Z,12Z,12'Z)-bis(octadeca-9,12-dienoate)
Application: Ionizable cationic, biodegradable amino lipid, LNP formation
CAS 2940241-38-1
MW: 927.5 D
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Methylcarbamyl PAF C-8
Methylcarbamyl PAF C-8

Item number: Cay9000332-1

Methylcarbamyl PAF C-8 is the C-8 analog of Methylcarbamyl PAF C-16. Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. It is nearly equipotent with PAF C-16 in its ability to induce platelet...
Keywords: 1-O-octyl-2-O-(N-methylcarbamoyl)-sn-glyceryl-3-phosphorylcholine
Application: Bioactive lipid assays
MW: 426.5 D
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9-keto Tafluprost
9-keto Tafluprost

Item number: Cay9000349-1

9-keto Tafluprost is a derivative of the FP receptor agonist tafluprost (Cay-10005440).Formal Name: 7-[(1R,2R,3R)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3-hydroxy-5-oxocyclopentyl]-5-heptenoic acid, 1-methylethyl ester. CAS Number: 261179-75-3. Molecular Formula: C25H32F2O5. Formula Weight: 450.5. Purity:...
Keywords: 7-[(1R,2R,3R)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3-hydroxy-5-oxocyclopentyl]-5-heptenoic acid, 1-methylethyl ester
Application: Tafluprost (FP receptor agonist) derivative
CAS 261179-75-3
MW: 450.5 D
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19-alkyne Cholesterol
19-alkyne Cholesterol

Item number: Cay16446-1

19-alkyne Cholesterol is an alkyne derivative of cholesterol (Cay-9003100). It has been used to track cholesterol localization and subcellular distribution in NIH3T3 cells and to study the role of cholesterol in hedgehog (Hh) signal transduction in Shh-LIGHT2 cells using click chemistry and various reporter...
Keywords: 19-ethynyl Cholesterol, 10-ethynyl-19-norcholest-5-en-3beta-ol
Application: Cholesterol alkyne derivative, click chemistry
CAS 2058319-71-2
MW: 396.7 D
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Teleocidin A1
Teleocidin A1

Item number: Cay25482-1

Teleocidin A1, also known as lyngbyatoxin A, is a fungal metabolite that has been isolated from S. mediocidicus and is the R enantiomer of (S)-teleocidin A. It acts as a tumor promoter, inducing ornithine decarboxylase activity in mouse skin, increasing adhesion of HL-60 human leukemia cells (ED50 = 7 ng/ml), and...
Keywords: Lyngbyatoxin A,...
Application: Fungal metabolite, tumor promoter
CAS 70497-14-2
MW: 437.6 D
From 498.00€ *
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327 from 345 pages