Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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Myricetin 3-galactoside
Myricetin 3-galactoside

Item number: Cay36467-1

Myricetin 3-galactoside is a flavonoid that has been found in M. communis and has diverse biological activities. It inhibits xanthine oxidase in a cell-free assay when used at a concentration of 100 µg/ml. Myricetin 3-galactoside is cytotoxic to K562 cells (IC50 = 220 µg/ml) and inhibits hydrogen peroxide-induced...
Keywords: Myricetin 3-O-galactoside, Myricetin 3-O-beta-D-galactopyranoside, Myricetin 3-O-beta-galactopyranoside, Myricetin...
Application: Bioactive flavonoid
CAS 15648-86-9
MW: 480.4 D
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10-methyl Lauric Acid
10-methyl Lauric Acid

Item number: Cay36504-1

10-methyl Lauric acid is a methyl branched-chain fatty acid., It has been found in the Gram-positive bacteria B. acetylicum, as well as the mandibular gland secretions of carpenter ant species, including C. herculeanus, C. ligniperda, and C. pennsylvanicus.Formal Name: 10-methyl-dodecanoic acid. CAS Number:...
Keywords: 10-methyl Dodecanoic Acid, 10-methyl-dodecanoic acid
Application: Methyl branched-chain fatty acid
CAS 7416-57-1
MW: 214.3 D
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NT1-O14B
NT1-O14B

Item number: Cay37095-25

NT1-O14B is a tryptamine-containing ionizable cationic lipidoid. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Intravenous administration of LNPs containing NT1-O14B and the cationic lipidoid 306-O12B-3 (Cay-37096) encapsulating antisense oligonucleotides (ASOs)...
Application: Cationic lipidoid
CAS 2739805-64-0
MW: 769.2 D
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9A1P9
9A1P9

Item number: Cay37276-1

9A1P9 is a multi-tail ionizable cationic phospholipid. It induces membrane destabilization and has been used for organ-selective mRNA delivery to the spleen and liver and CRISPR-Cas9 gene editing in mice.Formal Name: 2-(dioctylamino)ethyl nonyl hydrogen phosphate. CAS Number: 2760467-57-8. Molecular Formula:...
Keywords: 2-(dioctylamino)ethyl nonyl hydrogen phosphate
Application: Multi-tail ionizable phospholipid, membrane destabilization inducer, organ-selective mRNA delivery
CAS 2760467-57-8
MW: 491.7 D
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BPH-1358
BPH-1358

Item number: Cay37402-5

BPH-1358 is an inhibitor of undecaprenyl diphosphate synthase (UPPS, IC50 = 0.11 µM for the E. coli and S. aureus enzymes), an enzyme involved in bacterial cell wall biosynthesis. It is also an inhibitor of farnesyl diphosphate synthase (FPPS, IC50 = 1.8 µM for the human enzyme), an enzyme in the mevalonate pathway...
Keywords: NSC 50460, N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-[1,1'-biphenyl]-4,4'-dicarboxamide
Application: uppS inhibitor
CAS 5352-53-4
MW: 601.5 D
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3-(3-Hydroxyphenyl)propionic Acid sulfate
3-(3-Hydroxyphenyl)propionic Acid sulfate

Item number: Cay9004103-5

3-(3-Hydroxyphenyl)propionic acid (3-HPPA) sulfate is a metabolite of a variety of phenols, including ferulic acid (Cay-19871), dihydroferulic acid, and dihydrocaffeic acid (Cay-28390), and the glycosides echinacoside (Cay-29927) and acteoside. Urinary excretion of 3-HPPA sulfate is reduced in protein-deficient mice...
Keywords: 3-HPPA sulfate, 3-(sulfooxy)-benzenepropanoic acid
Application: Phenol / glycoside metabolite
CAS 86321-32-6
MW: 246.2 D
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Phytanic Acid methyl ester
Phytanic Acid methyl ester

Item number: Cay10007422-50

Phytanic acid methyl ester is a long-chain fatty acid methyl ester and esterified form of phytanic acid (Cay-90360) that has been found in Greek tobacco.Formal Name: 3,7,11,15-tetramethyl-hexadecanoic acid, methyl ester. CAS Number: 1118-77-0. Synonyms: Methyl Phytanate, SFE 21:0. Molecular Formula: C21H42O2....
Keywords: Methyl Phytanate, 3,7,11,15-tetramethyl-hexadecanoic acid, methyl ester
Application: Long-chain fatty acid methyl ester
CAS 1118-77-0
MW: 326.6 D
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alpha-Linolenic Acid ethyl ester
alpha-Linolenic Acid ethyl ester

Item number: Cay10008199-50

alpha-Linolenic acid ethyl ester is an esterified form of alpha-linolenic acid (Cay-90210, Cay-21910). It increases cyclin E levels and the activity of Cdk2/cyclin E, ERK, and JNK in hepatic stellate cells when used at a concentration of 50 µM. alpha-Linolenic acid ethyl ester (25 µg/ml) inhibits the growth of S....
Keywords: ALAEE, Ethyl Linolenate, Ethyl alpha-Linolenate, LAEE, Linolenic Acid ethyl ester, 9Z,12Z,15Z-octadecatrienoic acid, ethyl...
Application: Bioactive lipid assays
CAS 1191-41-9
MW: 306.5 D
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7alpha-hydroxy Cholesterol
7alpha-hydroxy Cholesterol

Item number: Cay20098-10

7alpha-hydroxy Cholesterol is an oxysterol and a precursor in the biosynthesis of the bile acids cholic acid (CA, Cay-20250) and chenodeoxycholic acid (CDCA, Cay-10011286). It is formed via the oxidation of cholesterol (Cay-9003100) by cholesterol 7alpha-hydroxylase/CYP7A1 in rat liver microsomes. 7alpha-hydroxy...
Keywords: cholest-5-ene-3beta,7alpha-diol
CAS 566-26-7
MW: 402.7 D
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7-keto Deoxycholic Acid
7-keto Deoxycholic Acid

Item number: Cay35264-10

7-keto Deoxycholic acid is a metabolite of the primary bile acid cholic acid (Cay-20250). Fecal levels of 7-keto deoxycholic acid are elevated in rats fed a diet supplemented with cholic acid compared with rats fed a control diet or a diet supplemented with cholesterol (Cay-9003100). Hepatic levels of 7-keto...
Keywords: 5beta-Cholanic Acid-3alpha,12alpha-diol-7-one, 7-keto DCA, (5beta)-3alpha,12alpha-dihydroxy-7-oxo-cholan-24-oic acid
Application: Cholic acid metabolite
CAS 911-40-0
MW: 406.6 D
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beta-Cortolone
beta-Cortolone

Item number: Cay36224-5

beta-Cortolone is a metabolite of the glucocorticoid cortisol (hydrocortisone, Cay-20739). It is formed from cortisol by 20beta-hydroxysteroid dehydrogenase (20beta-HSD) via a 5beta-tetrahydrocortisol (Cay-34195) intermediate. Urinary levels of beta-cortolone are decreased in postmenopausal women with endometrial...
Keywords: 20beta-Cortolone, NSC 56997, (5beta)-3alpha,17,20R,21-tetrahydroxy-pregnan-11-one
Application: Cortisol metabolite
CAS 667-66-3
MW: 366.5 D
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Sulfuretin
Sulfuretin

Item number: Cay36569-5

Sulfuretin is a flavonoid that has been found in R. verniciflua and has diverse biological activities. It inhibits mushroom tyrosinase activity (IC50 = 13.64 µM). Sulfuretin decreases cytotoxicity induced by infectious hematopoietic necrosis virus (IHNV) in JFSP cells and viral hemorrhagic septicemia virus (VHSV) in...
Keywords: 3',4',6-Trihydroxyaurone, 3',4',6-Trihydroxybenzalcoumaranone, Suphuretin,...
Application: Bioactive aurone flavonoid
CAS 120-05-8
MW: 270.2 D
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323 from 345 pages