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NBD-Stearic Acid
Item number: Cay10011299-5
NBD-Stearic acid is a derivative of the long-chain saturated fatty acid stearic acid (Cay-10011298) that contains the fluorophore nitrobenzoxadiazole (NBD) at C-18. NBD-conjugated long-chain saturated fatty acids have been used as probes to study fatty acid uptake and fatty acid binding proteins (FABPs).Formal Name:...
| Keywords: | NBD-C18:0, NBD-Octadecanoic Acid, 18-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)octadecanoic acid |
| Application: | Stearic acid derivative, fluorescent fatty acid uptake/FABP probe |
| MW: | 462.6 D |
From 45.00€
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13(Z)-Eicosenoic Acid
Item number: Cay26169-10
13(Z)-Eicosenoic acid is an omega-7 fatty acid found in a variety of fish from the Indian, Atlantic, and Pacific oceans. It increases triglyceride accumulation in 3T3-L1 cells when used at a concentration of 50 µM.CAS Number: 17735-94-3. Synonyms: C20:1(13Z), C20:1 n-7, cis-13-Eicosenoic Acid, FA 20:1, Paullinic...
| Keywords: | cis-13-Eicosenoic Acid, C20:1 n-7, C20:1(13Z), Paullinic Acid |
| Application: | omega-7 fatty acid |
| CAS | 17735-94-3 |
| MW: | 310.5 D |
From 49.00€
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1-1(Z)-Hexadecenyl-2-Palmitoyl-d9-sn-glycero-3-PE
Item number: Cay27590-1
1-1(Z)-Hexadecenyl-2-palmitoyl-d9-sn-glycero-3-PE is intended for use as an internal standard for the quantification of 1-1(Z)-hexadecenyl-2-palmitoyl-sn-glycero-3-PE (Cay-28349) by GC- or LC-MS. 1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PE is a plasmalogen that contains 1(Z)-hexadecanoic acid and palmitic acid...
| Keywords: | 1-1(Z)-Hexadecenyl-2-Palmitoyl-d9-sn-glycero-3-Phosphoethanolamine,... |
| Application: | GC-MS, LC-MS, internal standard, plasmalogen |
| CAS | 2738509-20-9 |
| MW: | 685 D |
From 434.00€
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Lipoamide
Item number: Cay35336-250
Lipoamide is an amide derivative of lipoic acid (Cay-10005728). It is an essential cofactor for enzymes in the citric acid cycle and enzymes involved in the catabolism of glycine and branched-chain amino acids (BCAAs). Lipoamide is covalently attached to lysine residues in proteins via lipoylation, a...
| Keywords: | (±)-Thioctic Acid amide, DL-alpha-Lipoic Acid amide, NSC 90787, alpha-Lipoamide, 1,2-dithiolane-3-pentanamide |
| Application: | Lipoic acid amide derivative |
| CAS | 940-69-2 |
| MW: | 205.3 D |
From 44.00€
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5-(3',4'-Dihydroxyphenyl)-gamma-Valerolactone
Item number: Cay36690-10
5-(3',4'-Dihydroxyphenyl)-gamma-valerolactone is an active metabolite of various polyphenols, including (-)-epicatechin (Cay-11807) and procyanidin (Cay-29763). It is formed from these polyphenols by gut microbiota. 5-(3',4'-Dihydroxyphenyl)-gamma-valerolactone is an inhibitor of matrix metalloproteinase-1 (MMP-1)...
| Keywords: | (±)-delta-(3,4-Dihydroxyphenyl)-gamma-Valerolactone, 5-(3',4'-Dihydroxyphenyl)-gamma-VL,... |
| Application: | Polyphenol active metabolite, MMP inhibitor |
| CAS | 21618-92-8 |
| MW: | 208.2 D |
From 100.00€
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LP-01
Item number: Cay37278-25
LP-01 is an ionizable cationic amino lipid (pKa = ~6.1). It has been used in the generation of lipid nanoparticles (LNPs). LNPs containing LP-01 and encapsulating both Cas9 mRNA and modified single-guide RNA (sgRNA) for the transport protein transthyretin (Ttr) induce gene editing in liver cells in mice in a...
| Keywords: | CIN-16645, 9Z,12Z-octadecadienoic acid,... |
| Application: | Ionizable amino lipid, LNP formation, sgRNA delivery |
| CAS | 1799316-64-5 |
| MW: | 852.3 D |
From 163.00€
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Mevalonate (lithium salt)
Item number: Cay37476-1
Mevalonate is an intermediate in the mevalonate pathway of cholesterol synthesis. It inhibits cell death induced by the HMG-CoA reductase inhibitor simvastatin (Cay-10010344, Cay-10010345) in C2C12 myoblasts when used at concentrations ranging from 80 to 110 µM. Mevalonate (500 µM) reverses decreases in...
| Keywords: | Mevalonic Acid, MVA, Pentanoic Acid, 3,5-dihydroxy-3-methyl-pentanoic acid, lithium salt |
| Application: | Mevalonate pathway Intermediate |
| CAS | 2618458-93-6 |
| MW: | 148.2 D |
From 45.00€
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Estriol 6 CMO, Highly Purified (1,3,5(10)-Estratrien-3,...
Item number: E3560-42.10
Synonyms:, 1,3,5(10)-Estratrien-3, 16a, 17b-triol 6-carboxymethoxime, CAS No: 37654-41-4, Molecular Formula: C20H25NO6, Molecular Weight: 375.42, Appearance: Supplied as a lyophilized powder. Reconstitute with ddH2O or an organic solvent such as Methanol or Acetonitrile. Precursor: 1,3,5(10)-Estratrien-3, 16alpha,...
| CAS | 37654-41-4 |
From 378.00€
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Oleoyl Serinol
Item number: Cay13637-10
Oleoyl serinol is an analog of ceramide and an agonist of the cannabinoid receptor GPR119 that has an EC50 value of 12 µM for stimulating secretion of GLP-1 in mouse endocrine GLUTag cells. It has been found in E. coli that express human microbiota N-acyl synthase (hmNAS) genes. It induces cell death of F-11 murine...
| Keywords: | N-Oleoyl Serinol, S-18, N-[2-hydroxy-1-(hydroxymethyl)ethyl]-9Z-octadecenamide |
| Application: | GPR119 agonist |
| CAS | 72809-08-6 |
| MW: | 355.6 D |
From 62.00€
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1,2,3-Tridocosanoyl Glycerol
Item number: Cay26847-500
1,2,3-Tridocosanoyl glycerol is a triacylglycerol that contains docosanoic acid (Cay-9000338) at the sn-1, sn-2, and sn-3 positions. Formulations containing 1,2,3-tridocosanoyl glycerol have been used to form the lipid matrices of nanostructured lipid carriers and solid lipid nanoparticles (SLNs). Formulations...
| Keywords: | Glycerol Tribehenate, Glycerol Tridocosanoate, TG(22:0/22:0/22:0), Tribehenin, Tridocosanoin, Tridocosanoylglycerol,... |
| Application: | Triacylglycerol |
| CAS | 18641-57-1 |
| MW: | 1059.8 D |
From 93.00€
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BLT-1
Item number: Cay34989-5
BLT-1 is an inhibitor of scavenger receptor B1 (SR-BI). It inhibits uptake of [3H]cholesteryl ester-HDL in LDL receptor-deficient CHO cells expressing mouse SR-BI ((ldlA[mSR-BI]) cells, IC50 = 0.11 µM) and the efflux of cholesterol from ldlA[mSR-BI] cells to HDL (IC50 = 0.15 µM). BLT-1 (8 µM) induces developmental...
| Keywords: | Block Lipid Transport-1, 2-(2-hexylcyclopentylidene)-hydrazinecarbothioamide |
| Application: | SR-BI inhibitor |
| CAS | 321673-30-7 |
| MW: | 241.4 D |
From 67.00€
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Acetyl-CoA Synthase Inhibitor
Item number: Cay36023-5
Acetyl-CoA synthase inhibitor is an inhibitor of acetyl-CoA synthetase 2 (ACCS2, IC50 = 1.214 µM). It reduces oleic acid-induced increases in the number of histone H2AX-positive cells, a marker of DNA damage, in cultured human immortalized hepatocytes when used at a concentration of 50 µM.Formal Name:...
| Keywords: | ACCS2 Inhibitor, MDK6149, VY-3-249, N-(2,3-di-2-thienyl-6-quinoxalinyl)-N'-(2-methoxyethyl)-urea |
| Application: | ACCS2 inhibitor |
| CAS | 508186-14-9 |
| MW: | 410.5 D |
From 149.00€
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