Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
Close window
Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

32 from 345 pages
No results were found for the filter!
Stearidonic Acid
Stearidonic Acid

Item number: Cay90320-1

Stearidonic acid is an 18-carbon, omega-3 fatty acid which is a dietary precursor to EPA and DHA. Stearidonic acid is present in small amounts in seed oils, especially black currant seed oil. [Matreya, LLC. Catalog No. 1276]Formal Name: 6Z,9Z,12Z,15Z-octadecatetraenoic acid. CAS Number: 20290-75-9. Synonyms: FA...
Keywords: Moroctic Acid, 6Z,9Z,12Z,15Z-octadecatetraenoic acid
Application: Bioactive lipid assays
CAS 20290-75-9
MW: 276.4 D
From 71.00€ *
Review
Lipid-based Drug Delivery Tools
1,2-Dimyristoyl-sn-glycero-3-PC
1,2-Dimyristoyl-sn-glycero-3-PC

Item number: Cay15097-1

1,2-Dimyristoyl-sn-glycero-3-PC (DMPC) is a phospholipid containing 14:0 fatty acids at the sn-1 and sn-2 positions. It is a synthetic phosopholipid that has been used for liposome production in order to study the properties of lipid bilayer.Formal Name: 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine. CAS Number:...
Keywords: 1,2-Dimyristoyl-sn-glycero-3-Phosphocholine, 1,2-DMPC, 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine
Application: Liposome production
CAS 18194-24-6
MW: 677.9 D
From 147.00€ *
Review
Lipid-based Drug Delivery Tools
DLin-MC3-DMA
DLin-MC3-DMA

Item number: Cay34364-10

DLin-MC3-DMA is an ionizable cationic amino lipid (apparent pKa = 6.44) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of Factor VII siRNA in DLin-MC3-DMA-containing LNPs reduces plasma Factor VII protein levels in mice. Formulations containing...
Keywords: MC3, 4-(dimethylamino)-butanoic acid, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester
Application: Ionizable amino lipid
CAS 1224606-06-7
MW: 642.1 D
From 102.00€ *
Review
(±)15-HEPE
(±)15-HEPE

Item number: Cay32700-25

(±)15-HEPE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEPE and 15(S)-HEPE (Cay-32710). 15(S)-HEPE is formed from EPA via a 15(S)-HpEPE (Cay-42710) intermediate, which is produced by 15-lipoxygenase (15-LO) and reduced by glutathione peroxidase (GPX). (±)15-HEPE is active against P. acnes and S. aureus...
Keywords: (±)15-hydroxy Eicosapentaenoic Acid, (±)15-hydroxy EPA, 15-hydroxy-5Z,8Z,11Z,13E,17Z-eicosapentaenoic acid
Application: Bioactive lipid studies
CAS 88852-33-9
MW: 318.5 D
From 88.00€ *
Review
PAMAM Dendrimer G6.0 Amine (water solution)
PAMAM Dendrimer G6.0 Amine (water solution)

Item number: Cay39076-100

PAMAM dendrimer G6.0 amine (PAMAM G6.0) is a polyamidoamine (PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vivo. It is approximately 67 Å in diameter and has 256 surface groups. PAMAM G6.0 is active against clinical isolates of several bacteria (MICs = 0.25-25 µg/ml). It...
Keywords: PAMAM G6.0, Polyamidoamine Dendrimer G6.0
Application: Amine-terminated PAMAM dendrimer, in vivo drug delivery
CAS 163442-69-1
MW: 58046.1 D
From 116.00€ *
Review
Iloprost
Iloprost

Item number: Cay18215-1

Iloprost is a second generation structural analog of prostacyclin (PGI) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the human recombinant IP and EP1 receptors with a Ki of 11 nM. Iloprost constricts the isolated...
Keywords: Ciloprost, 6,9alpha-methylene-11alpha,15S-dihydroxy-16-methyl-prosta-5E,13E-dien-18-yn-1-oic acid
Application: PGI analog
CAS 78919-13-8
MW: 360.5 D
From 44.00€ *
Review
C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)
C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)

Item number: Cay24879-1

C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide (Cay-24870, Cay-24871, Cay-24872) that contains an adamantanyl group in place of the fatty acyl chain. It inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay when used at a...
Keywords: AdaGb3, Adamantyl Gb3, C2 Adamantanyl Ceramide Trihexoside (d18:1/2:0),...
Application: Bioactive sphingolipid
CAS 261155-87-7
MW: 962.17 D
631.00€ *
Review
Docosahexaenoic Acid (peroxide free)
Docosahexaenoic Acid (peroxide free)

Item number: Cay17932-10

Docosahexaenoic acid (DHA) is a long-chain omega-3 polyunsaturated fatty acid (PUFA) found in fish and algal oils. It comprises approximately 40% of total brain PUFAs and is abundant in grey matter and retinal membranes. DHA typically represents 0.52-7.5% of human total plasma fatty acids. It is produced from...
Keywords: 4,7,10,13,16,19-Docosahexaenoic Acid, C22:6 n-3, C22:6(4Z,7Z,10Z,13Z,16Z,19Z), Cervonic Acid, DHA,...
Application: Long-chain omega-3 PUFA
CAS 6217-54-5
MW: 328.5 D
From 38.00€ *
Review
Aranidipine
Aranidipine

Item number: Cay40813-10

Aranidipine is an antagonist of voltage-gated calcium channel Cav3.2. It inhibits inward currents in Xenopus oocytes expressing human Cav3.2 channels when used at a concentration of 10 µM. Aranidipine (10 mg/kg) decreases mean blood pressure and increases heart rate in spontaneously hypertensive rats (SHRs). It...
Keywords: MPC-1304, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-yridinedicarboxylic acid, 3-methyl 5-(2-oxopropyl) ester
Application: Cav3.2 antagonist
CAS 86780-90-7
MW: 388.4 D
From 73.00€ *
Review
Pseudoginsenoside RT5
Pseudoginsenoside RT5

Item number: Cay42388-1

Pseudoginsenoside RT5 is an ocotillol-type ginsenoside that has been found in P. quinquefolium. SMILES C[C@]12[C@]3([C@@]([C@@H](C[C@]1([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])[C@H](C2)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO)C)O)([H])[C@]([C@]6(O[C@H](CC6)C(C)(O)C)C)([H])CC3)C InChi Code...
Keywords: 24(R)-Pseudoginsenoside RT5, Ginsenoside RT-5, (3beta,6alpha,12beta,24R)-20,24-epoxy-3,12,25-trihydroxydammaran-6-yl,...
Application: Ginsenoside
CAS 98474-78-3
MW: 654.87 D
From 56.00€ *
Review
Grayanotoxin I
Grayanotoxin I

Item number: Cay42644-100

Grayanotoxin I is a diterpene toxin that has been found in R. ponticum nectar, a component of mad honey. It increases resting sodium permeability in squid axonal membranes when used at a concentration of 10 µM. Grayanotoxin I (0.25, 0.5, and 1 mg/kg) induces proteinuria and reduces serum levels of alanine...
Keywords: Acetylandromedol, Andromedotoxin, Asebotoxin, GTX I, NSC 26711, Rhodotoxin, grayanotoxane-3beta,5,6beta,10,14R,16-hexol,...
Application: Diterpene toxin, reversible Nav1.x agonist
CAS 4720-09-6
MW: 412.52 D
From 186.00€ *
Review
Pregnanolone
Pregnanolone

Item number: Cay42751-1

Pregnanolone is a neurosteroid and an active metabolite of pregnenolone (Cay19864). It is formed from pregnenolone via the intermediates progesterone (Cay15876) and 5beta-dihydroprogesterone (Cay34644). Pregnanolone enhances the binding of flunitrazepam to GABAA receptors in rat brain homogenate (EC50 = 237 nM) and...
Keywords: 3alpha,5beta-P, 3alpha,5beta-Tetrahydroprogesterone, 5beta-Pregnan-3alpha-ol-20-one, Eltanolone, NSC 82867, SKF 6455,...
Application: Pregnenolone active metabolite, neurosteroid
CAS 128-20-1
MW: 318.5 D
From 49.00€ *
Review
32 from 345 pages