Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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N-Palmitoyl Phenylalanine
N-Palmitoyl Phenylalanine

Item number: Cay20066-1

An N-acyl amide, inhibits pre-mRNA splicing in HeLa cell nuclear lysates (IC50 = ~150 µM) but has no splicing activity in intact HeLa cells. Formulation: A crystalline solid. InChI:...
Keywords: N-Hexadecanoyl Phenylalanine, N-(1-oxohexadecyl)-L-phenylalanine
Application: N-acyl amide
CAS 37571-96-3
MW: 403.6 D
From 251.00€ *
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DMPE-MPEG(2000)
DMPE-MPEG(2000)

Item number: Cay34649-50

DMPE-MPEG(2000) is a PEGylated derivative of 1,2-dimyristoyl-rac-glycero-3-PE (DMPE). It has been used in the synthesis of nanostructured lipid carriers (NLCs) for use in ocular administration of ciprofloxacin (Cay-14286).Formal Name:...
Keywords: 1,2-Dimyristoyl-rac-glycero-3-PE-methoxy-Polyethyleneglycol-2000, 1,2-DMPE-MPEG(2000),...
Application: DMPE PEGylated form
CAS 1254157-61-3
409.00€ *
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RM 137-15
RM 137-15

Item number: Cay38918-1

RM 137-15 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. LNPs containing RM 137-15 and encapsulating mRNA encoding a fluorescent reporter increase fluorescence in the livers of mice.Formal Name:...
Keywords: (9Z,9'Z)-((3,3'-((2-(4-methylpiperazin-1-yl)ethyl)azanediyl)bis(propanoyl))bis(oxy))bis(octadec-9-ene-18,7-diyl)...
Application: Ionizable cationic lipid, LNP formation
MW: 1441.3 D
From 108.00€ *
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Polysarcosine50
Polysarcosine50

Item number: Cay39049-1

Polysarcosine50 is an amine-functionalized hydrophilic polymer. It has been used in the synthesis of catechol-functionalized copolypeptoids that can be used to solubilize manganese oxide nanoparticles in aqueous solvents. Surface modification of liposomes with polysarcosine polymers between 10 and 400 units long...
Keywords: pSar50, N-butyl-2-(methyl((methylamino)methyl)amino)acetamide
Application: Amine-functionalized hydrophilic polymer, LNP, immunogenicity reducer
From 38.00€ *
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DSPE-Polysarcosine66
DSPE-Polysarcosine66

Item number: Cay39052-10

DSPE-polysarcosine66 is an amine-functionalized hydrophilic polymer. It is a polysarcosine-labeled form of 1,2-distearoyl-rac-glycero-3-phosphoethanolamine (DSPE). Polysarcosines have been used as alternatives to PEGylation in lipid nanoparticles (LNPs) and to reduce the immunogenicity of administered proteins in...
Keywords: 1,2-Dioctadecanoyl-rac-glycero-3-Phosphoethanolamine-Polysarcosine66, 1,2-Distearoyl-rac-glycero-3-PE Polysarcosine66,...
Application: Amine-functionalized hydrophilic polymer, LNP, immunogenicity reducer
MW: 862.2 D
From 83.00€ *
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N-Palmitoyl-DPPE (triethylammonium salt)
N-Palmitoyl-DPPE (triethylammonium salt)

Item number: Cay39195-1

N-Palmitoyl-DPPE is an N-acyl-phosphatidylethanolamine (NAPE).Formal Name: hexadecanoic acid, (1R)-1-(3-hydroxy-3-oxido-8-oxo-2,4-dioxa-7-aza-3-phosphatricos-1-yl)-1,2-ethanediyl ester, monotriethylammonium salt. Synonyms: N-Palmitoyl-1,2-Dipalmitoyl-sn-glycero-3-Phosphoethanolamine,...
Keywords: NAPE(16:0/16:0/16:0), N-Hexadecanoyl-1,2-Dihexadecanoyl-sn-glycero-3-Phosphoethanolamine,...
Application: N-acyl-phosphatidylethanolamine, hormone
MW: 1031.6 D
From 38.00€ *
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SAINT C-18
SAINT C-18

Item number: Cay39709-1

SAINT C-18 is a cationic lipid that has been used in the formation of liposomes for the delivery of plasmid DNA, proteins, siRNA, and small molecules. Complexes of SAINT C-18 with plasmid DNA encoding pigment epithelium-derived factor (PEDF) inhibit corneal neovascularization induced by complexes of SAINT C-18 with...
Keywords: SAINT-18, SAINT-2, SAINT-7, Synthetic Amphiphile INTeration C-18,...
Application: Cationic lipid, liposome formation
CAS 187587-97-9
MW: 644.5 D
From 147.00€ *
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SMA-200
SMA-200

Item number: IAX-700-202-3500

A nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilized by a chaperone molecular annulus. Lipodisq(TM) polymers are available as 4 defined structures (1:1, 2:1, 3:1, and 4:1 Styrene to MaleicAcid (SMA) rations) each individually operational within a selected pH...
Keywords: Lipodisq(TM) Styrene:Maleic Acid Copolymer 2:1
Application: Drug delivery system
MW: 7,500 D
From 173.00€ *
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SMA-300
SMA-300

Item number: IAX-700-203-3500

A nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilized by a chaperone molecular annulus. Lipodisq(TM) polymers are available as 4 defined structures (1:1, 2:1, 3:1, and 4:1 Styrene to MaleicAcid (SMA) rations) each individually operational within a selected pH...
Keywords: Lipodisq(TM) Styrene:Maleic Acid Copolymer 3:1
Application: Drug delivery system
MW: 9,500 D
From 173.00€ *
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DMPC (1,2-Dimyristoyl-sn-glycero-3-phosphocholine) (14:0 PC)
DMPC (1,2-Dimyristoyl-sn-glycero-3-phosphocholine) (14:0 PC)

Item number: IAX-700-400-5050

1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid utilized in liposomes and lipid bilayers for the study of biological membranes. Its utility extends to investigating the influence of lipids on enzymatic activity and protein function when formulated into nanodiscs, LNP or liposomes....
Keywords: 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (14:0 PC)
Application: Synthetic phospholipid
CAS 18194-24-6
MW: 677,9 D
From 77.00€ *
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Ciclesonide
Ciclesonide

Item number: LKT-C324091.100

Ciclesonide is an anti-inflammatory corticosteroid. Its active metabolite and several ciclesonide-acetal derivatives have been found to block RNA replication of the SARS-Cov-2 virus. Ciclesonide also inhibits lung cancer stem cells through Hedgehog signaling-mediated SOX2 regulation. Solubility: Insoluble in water....
Keywords: Alvesco, Omnaris, Zetonna, RPR251526, (R)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal...
Application: Corticosteroid
CAS 126544-47-6
MW: 540.7 D
From 139.00€ *
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Lauroylsarcosine (sodium salt)
Lauroylsarcosine (sodium salt)

Item number: Cay33718-100

Lauroylsarcosine is a fatty acid amide and detergent. It has been used to solubilize recombinant and membrane proteins.Formal Name: N-methyl-N-(1-oxododecyl)-glycine, monosodium salt. CAS Number: 137-16-6. Synonyms: Sarkosyl, SDDS, Sodium Lauroyl Sarcosinate, Sodium N-dodecanoyl Sarcosinate. Molecular Formula:...
Keywords: Sarkosyl, SDDS, Sodium Lauroyl Sarcosinate, Sodium N-dodecanoyl Sarcosinate, N-methyl-N-(1-oxododecyl)-glycine, monosodium...
Application: Fatty acid amide, detergent
CAS 137-16-6
MW: 293.4 D
From 56.00€ *
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314 from 345 pages