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C13-112-tri-tail
Item number: Cay38383-1
C13-112-tri-trail is an ionizable cationic lipid.Formal Name: 14-(2-hydroxytridecyl)-17,20-dioxa-14,23-diazahexatriacontane-12,25-diol. CAS Number: 1381861-96-6. Molecular Formula: C45H94N2O5. Formula Weight: 743.2. Purity: >90%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMSO:...
| Keywords: | 14-(2-hydroxytridecyl)-17,20-dioxa-14,23-diazahexatriacontane-12,25-diol |
| Application: | Ionizable cationic lipid |
| CAS | 1381861-96-6 |
| MW: | 743.2 D |
From 38.00€
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Lipid M
Item number: Cay38775-1
Lipid M is an ionizable cationic lipid (pKa = 6.75) that has been used in the generation of lipid nanoparticles (LNPs) for mRNA delivery in vivo. LNPs containing lipid M and encapsulating mRNA encoding influenza virus genes increase anti-influenza virus IgG titers in cynomolgus monkeys without inducing local edema,...
| Keywords: | 2-octyl-decanoic acid, 7-[(2-hydroxyethyl)[8-(nonyloxy)-8-oxooctyl]amino]heptyl ester |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2089251-57-8 |
| MW: | 710.2 D |
From 138.00€
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1,2-Dihexanoyl-sn-glycero-3-PS (sodium salt)
Item number: Cay39190-1
1,2-Dihexanoyl-sn-glycero-3-PS is a phospholipid containing hexanoic acid at the sn-1 and sn-2 positions.Formal Name: (2S,8R)-2-amino-5-hydroxy-11-oxo-8-[(1-oxohexyl)oxy]-4,6,10-trioxa-5-phosphahexadecanoic acid, 5-oxide, monosodium salt. CAS Number: 321862-85-5. Synonyms:...
| Keywords: | 1,2-Dicaproyl-sn-glycero-3-phosphatidylserine, 1,2-Dicaproyl-sn-glycero-3-phosphoserine,... |
| Application: | Phospholipid |
| CAS | 321862-85-5 |
| MW: | 477.4 D |
From 49.00€
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DLin-MC2-DMA
Item number: Cay39731-1
DLin-MC2-DMA is an ionizable cationic lipid (pKa = 5.64) that has been used in the formation of lipid nanoparticles (LNPs). LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding mouse coagulation Factor VII (FVII) reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg).Formal Name:...
| Keywords: | MC2, N,N-dimethyl-beta-alanine (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 1221271-55-1 |
| MW: | 628.1 D |
From 38.00€
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Lipid C2
Item number: Cay39783-1
Lipid C2 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs) for mRNA delivery in vivo. LNPs containing lipid C2 and encapsulating an mRNA reporter selectively accumulate in the liver and spleen but not the heart, lungs, or kidneys in mice. LNPs containing lipid C2 and...
| Keywords: | N1,N4-bis[2-[bis(2-hydroxytetradecyl)amino]ethyl]-1,4-piperazinedipropanamide |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 3003022-09-8 |
| MW: | 1163.9 D |
From 103.00€
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Juglanin
Item number: Cay39824-1
Juglanin is a flavonol that has been found in J. mandshurica and has diverse biological activities. It reduces the levels of reactive oxygen species (ROS) increased by oscillatory shear stress (OSS) in human aortic endothelial cells (HAECs) when used at concentrations of 2.5 and 5 µM. It also reduces OSS-induced...
| Keywords: | Kaempferol-3-O-arabinofuranose, 3-(alpha-L-arabinofuranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Application: | Bioactive flavonol |
| CAS | 5041-67-8 |
| MW: | 418.4 D |
From 93.00€
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12-oxo Stearic Acid
Item number: Cay40259-100
12-oxo Stearic acid is a saturated oxo fatty acid (SOFA) and metabolite of ricinoleic acid (Cay-10009369) that has been found in cow and goat milk. Dietary administration of 12-oxo stearic acid (0.25%) induces encephalomalacia in chicks fed a vitamin E-deficient diet.Formal Name: 12-oxo-octadecanoic acid. CAS...
| Keywords: | 12-keto Octadecanoic Acid, 12-keto Stearic Acid, 12-oxo C18:0, 12-oxo Octadecanoic Acid, NSC 2103, 12-oxo-octadecanoic acid |
| Application: | Ricinoleic acid metabolite, saturated oxo fatty acid (SOFA) |
| CAS | 925-44-0 |
| MW: | 298.5 D |
From 231.00€
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1-A-N
Item number: Cay40500-1
1-A-N is an ionizable cationic lipid (pKa = 6.8) that has been used in the generation of lipid nanoparticles (LNPs) for siRNA delivery in vivo. LNPs containing 1-A-N and encapsulating siRNA targeting the gene encoding CD45 reduce its gene expression in splenic T cells in mice.Formal Name:...
| Keywords: | 3-(2-((3r,5r,7r)-adamantan-1-yl)acetoxy)-2-((((3-(pyrrolidin-1-yl)propoxy)carbonyl)oxy)methyl)propyl... |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 698 D |
From 72.00€
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C9-200
Item number: Cay40862-1
C9-200 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs). LNPs containing C9-200 and encapsulating mRNA encoding erythropoietin (EPO) increase serum EPO levels in mice. LNPs containing C9-200 and encapsulating mRNA encoding the Cas9 nuclease and small-guide RNA (sgRNA)...
| Keywords: | 1,1'-((2-(4-(2-((2-(bis(2-hydroxynonyl)amino)ethyl)(2-hydroxynonyl)amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(nonan-2-ol) |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 926.5 D |
From 48.00€
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Lipid N2-3L
Item number: Cay40911-1
Lipid N2-3L is an ionizable cationic lipid (pKa = 8.99) that has been used in the generation of supramolecular lipid nanoparticles (SMLNPs) encapsulating mRNA for use in vitro and in vivo. SMLNPs containing lipid N2-3L and encapsulating a luciferase reporter accumulate at the site of injection and in the draining...
| Keywords: | 9Z-octadecenoic acid,... |
| Application: | Ionizable cationic lipid, SMLNP generation |
| CAS | 2924606-55-1 |
| MW: | 840.3 D |
From 116.00€
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N-Lithocholyl-L-Leucine
Item number: Cay40931-1
N-Lithocholyl-L-leucine is a bile acid conjugate composed of lithocholic acid (Cay-20253) and L-leucine (Cay-34342). It has been used in the formation of hydrogels.Formal Name: N-[(3alpha,5beta)-3-hydroxy-24-oxocholan-24-yl]-L-leucine. CAS Number: 2095154-73-5. Molecular Formula: C30H51NO4. Formula Weight: 489.7....
| Keywords: | N-[(3alpha,5beta)-3-hydroxy-24-oxocholan-24-yl]-L-leucine |
| Application: | Bile acid conjugate, hydrogel formation |
| CAS | 2095154-73-5 |
| MW: | 489.7 D |
From 58.00€
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Q1-ALC-0315 (iodide)
Item number: Cay41240-1
Q1-ALC-0315 is a cationic quaternary ammonium lipid derivative of the ionizable cationic lipid ALC-0315 (Cay-34337) that has been used in the generation of lipid nanoparticles (LNPs) for use in vivo. LNPs containing Q1-ALC-0315 and ALC-0315 as a cationic lipid pair (CLP) and encapsulating mRNA encoding a luciferase...
| Keywords: | 6-((2-hexyldecanoyl)oxy)-N-(6-((2-hexyldecanoyl)oxy)hexyl)-N-(4-hydroxybutyl)-N-methylhexan-1-aminium, monoiodide |
| Application: | Ionizable cationic lipid ALC-0315 cationic quaternary ammonium lipid derivative, LNP formation |
| MW: | 908.2 D |
From 44.00€
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