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Lipid C3
Item number: Cay39516-1
Lipid C3 is an ionizable cationic lipid (pKa = 5.05-5.671). It has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. Intracerebroventricular administration of LNPs containing lipid C3 and encapsulating mRNA encoding alpha-L-iduronidase (Idua) to neonates increase...
| Keywords: | C16-6,... |
| Application: | Ionizable cationic lipid, formation |
| CAS | 2639634-93-6 |
| MW: | 1533.6 D |
From 127.00€
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VL422
Item number: Cay39874-1
VL422 is an ionizable cationic lipid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA for gene editing in vitro and in vivo. LNPs containing VL422 and encapsulating Cas9 mRNA and sgRNA targeting the gene encoding...
| Keywords: | octanedioic acid, 1,1'-[2-[[[[3-(diethylamino)propoxy]carbonyl]oxy]methyl]-1,3-propanediyl] 8,8'-bis(1-octylnonyl) ester |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2765519-47-7 |
| MW: | 1052.6 D |
From 112.00€
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Lipid 50
Item number: Cay39877-1
Lipid 50 is an ionizable cationic amino lipid.Formal Name: 2-((4-(((2-(pyrrolidin-1-yl)ethyl)carbamoyl)oxy)decanoyl)oxy)propane-1,3-diyl (9Z,9'Z,12Z,12'Z)-bis(octadeca-9,12-dienoate). CAS Number: 2440135-57-7. Molecular Formula: C56H98N2O8. Formula Weight: 927.4. Purity: >95%. Formulation: (Request formulation...
| Keywords: | 2-((4-(((2-(pyrrolidin-1-yl)ethyl)carbamoyl)oxy)decanoyl)oxy)propane-1,3-diyl (9Z,9'Z,12Z,12'Z)-bis(octadeca-9,12-dienoate) |
| Application: | Ionizable cationic amino lipid |
| CAS | 2440135-57-7 |
| MW: | 927.4 D |
From 172.00€
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Lipid C-1
Item number: Cay39975-1
Lipid C-1 is an ionizable cationic amino lipid and a derivative of SM-102 (Cay-33474). It has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro. LNPs containing lipid C-1 and encapsulating an mRNA reporter induce higher luciferase expression in Calu-3 cells than SM-102.Formal...
| Keywords: | Lipid 142, 8-[(3-hydroxypropyl)[6-oxo-6-(undecyloxy)hexyl]amino]-octanoic acid, 1-octylnonyl ester |
| Application: | Ionizable cationic amino lipid, LNP formation |
| CAS | 2244715-87-3 |
| MW: | 724.2 D |
From 38.00€
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m-isobutyl Ibuprofen
Item number: Cay40127-10
m-isobutyl Ibuprofen is a potential impurity in commercial preparations of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor ibuprofen.Formal Name: alpha-methyl-3-(2-methylpropyl)-benzeneacetic acid. CAS Number: 66622-47-7. Synonyms: Ibuprofen Impurity A, meta-isobutyl Ibuprofen. Molecular Formula:...
| Keywords: | meta-isobutyl Ibuprofen, Ibuprofen Impurity A, alpha-methyl-3-(2-methylpropyl)-benzeneacetic acid |
| Application: | Commercial ibuprofen preparation potential impurity |
| CAS | 66622-47-7 |
| MW: | 206.3 D |
From 97.00€
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Eupafolin
Item number: Cay40138-1
Eupafolin is a flavonoid that has been found in E. adenophorum and has diverse biological activities. It inhibits iron-dependent lipid peroxidation in a cell-free assay (IC50 = 7.9 µM). Eupafolin (50-150 µM) inhibits prion protein 106-126 (PrP106-126) aggregation in a cell-free assay and reduces PrP106-126-induced...
| Keywords: | 6-Methoxyluteolin, Nepetin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one |
| Application: | Bioactive flavonoid |
| CAS | 520-11-6 |
| MW: | 316.3 D |
From 88.00€
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Ombuin
Item number: Cay40217-1
Ombuin is a flavonoid that has been found in B. balsamifera and has diverse biological activities. It is an antagonist of M1 muscarinic acetylcholine receptors (mAChRs, Ki = 42 µM in CHO-K1 cells expressing the human receptor). Ombuin is cytotoxic to HepG2 hepatocellular carcinoma cells (IC50 = 1.5 µg/ml). In vivo,...
| Keywords: | NSC 675952, 3,5-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one |
| Application: | Bioactive flavonoid |
| CAS | 529-40-8 |
| MW: | 330.3 D |
From 73.00€
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Formosanin C
Item number: Cay40236-1
Formosanin C is a diosgenin saponin that has been found in P. formosana and has diverse biological activities. It is active against C. albicans (MIC = 1 µg/ml) and inhibits C. albicans biofilm formation (MIC = 25 µg/ml). Formosanin C (0.625-5 µM) inhibits LPS-induced production of prostaglandin E2 (PGE2, Cay-14010)...
| Keywords: | NSC 306864, Paris Saponin II, Polyphyllin B, PS II, (3beta,25R)-spirost-5-en-3-yl... |
| Application: | Bioactive diosgenin saponin |
| CAS | 50773-42-7 |
| MW: | 1015.2 D |
From 72.00€
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C14-A1
Item number: Cay40256-1
C14-A1 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs). LNPs containing C14-A1 and encapsulating mRNA expressing forkhead box protein P3 (FOXP3) increase FOXP3 levels in primary human T cells. LNPs containing C14-A1 and encapsulating mRNA expressing FOXP3 also reduce...
| Keywords: | 1,1'-((5-(4-(2-((5-(bis(2-hydroxytetradecyl)amino)pentyl)(2-hydroxytetradecyl)amino)ethyl)piperazin-1-yl)pentyl)azanediyl)... |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 1361.4 D |
From 93.00€
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Artemitin
Item number: Cay40269-10
Artemitin is a flavonoid that has been found in A. annua and has diverse biological activities. It scavenges peroxyl radicals in a cell-free assay in a concentration-dependent manner. Artemitin inhibits 5-lipoxygenase (5-LO) with an IC50 value of 54.6 µM. It is active against P. falciparum (IC50 = 26 µM). Artemitin...
| Keywords: | Artemetin, Artemisetin, 2-(3,4-dimethoxyphenyl)-5-hydroxy-3,6,7-trimethoxy-4H-1-benzopyran-4-one |
| Application: | Bioactive flavonoid |
| CAS | 479-90-3 |
| MW: | 388.4 D |
From 212.00€
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5,7,3',4'-Tetramethoxyflavone
Item number: Cay40272-100
5,7,3',4'-Tetramethoxyflavone is a flavone that has been found in M. paniculata and has diverse biological activities. It selectively inhibits multidrug resistance-associated protein 1 (MRP1) over MRP2 (IC50s = 7.9 and >50 µM, respectively). 5,7,3',4'-Tetramethoxyflavone (0.03-30 µM) inhibits LPS-induced nitric...
| Keywords: | 5,7,3',4'-tetramethyl Luteolin ether, Methoxyluteolin, Tetramethyl camphoral,... |
| Application: | Bioactive flavone |
| CAS | 855-97-0 |
| MW: | 342.3 D |
From 53.00€
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8-Shogaol
Item number: Cay40273-1
8-Shogaol is a phenol that has been found in Z. officinale and has diverse biological activities. It is an inhibitor of TGF-beta-activated kinase 1 (TAK1, IC50 = 5.027 nM). 8-Shogaol is also an inhibitor of COX-2 (IC50 = 32 µM). It reduces IL-17-induced secretion of IL-8 from SW 982 synovial sarcoma cells and...
| Keywords: | 1-(4-hydroxy-3-methoxyphenyl)-4-dodecen-3-one |
| Application: | Bioactive polyphenol |
| CAS | 36700-45-5 |
| MW: | 304.4 D |
From 118.00€
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