No results were found for the filter!
Monascin
Item number: Cay39510-1
Monascin is an azaphilonoid pigment that has been found in the fungus Monascus and has diverse biological activities. It induces peroxisome proliferator-activated receptor alpha (PPARalpha) activity in a coactivator assay (IC50 = 2,038 nM) and inhibits oleic acid-induced fatty acid uptake, lipogenesis, and fatty...
| Keywords: | (3S,3aR,9aR)-3a,4,8,9a-tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propen-1-yl-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione |
| Application: | Bioactive azaphilonoid pigment |
| CAS | 21516-68-7 |
| MW: | 358.4 D |
From 429.00€
*
1-Stearoyl-sn-glycerol
Item number: Cay39519-100
1-Stearoyl-sn-glycerol is a monoacylglycerol that contains stearic acid (Cay-10011298) at the sn-1 position.Formal Name: octadecanoic acid, (2S)-2,3-dihydroxypropyl ester. CAS Number: 22610-61-3. Synonyms: MG(18:0/0:0/0:0), L-(+)-1-Monostearin, 1-Octadecanoyl-sn-glycerol. Molecular Formula: C21H42O4. Formula Weight:...
| Keywords: | 1-Octadecanoyl-sn-glycerol, L-(+)-1-Monostearin, MG(18:0/0:0/0:0), octadecanoic acid, (2S)-2,3-dihydroxypropyl ester |
| Application: | Monoacylglycerol |
| CAS | 22610-61-3 |
| MW: | 358.6 D |
From 83.00€
*
RP 70676
Item number: Cay39529-100
RP 70676 is an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT, IC50 = 44 nM for the rabbit enzyme). It reduces plasma and arterial cholesterol levels in rabbits when administered at a dose of 1 mg/kg.Formal Name: 1-[5-[(4,5-diphenyl-1H-imidazol-2-yl)thio]pentyl]-3,5-dimethyl-1H-pyrazole. CAS Number:...
| Keywords: | 1-[5-[(4,5-diphenyl-1H-imidazol-2-yl)thio]pentyl]-3,5-dimethyl-1H-pyrazole |
| Application: | ACAT inhibitor |
| CAS | 136609-26-2 |
| MW: | 416.6 D |
From 444.00€
*
A1-28
Item number: Cay39590-10
A1-28 is a disulfide bond-containing ionizable cationic lipid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA for genome editing in vitro.Formal Name: bis(2-(dodecyldisulfaneyl)ethyl)...
| Keywords: | AMAP-O16B, bis(2-(dodecyldisulfaneyl)ethyl)... |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 1142.9 D |
From 238.00€
*
BODIPY 480/508-Cholesteryl Linoleate
Item number: Cay39684-1
BODIPY 480/508-cholesteryl linoleate is a cell-permeable and fluorescently tagged derivative of cholesteryl linoleate (Cay-22597). BODIPY 480/508-cholesteryl linoleate displays excitation/emission maxima of 480/508 nm, respectively, and has been used to monitor cholesterol trafficking in isolated human...
| Keywords: | BODIPY 480/508-Cholesterol Linoleate,... |
| Application: | Fluorescently tagged cholesterol ester, cholesterol trafficking monitoring |
| CAS | 2260795-60-4 |
| MW: | 839 D |
From 295.00€
*
IAJD93
Item number: Cay39688-10
IAJD93 is an ionizable amphiphilic Janus dendrimer (IAJD) delivery system for mRNA (pKa = 6.25). It co-assembles with mRNA to form dendrimersome nanoparticles (DNPs) in acetate buffer. IAJD93 co-assembled with luciferase mRNA delivers the mRNA to the spleen, liver, lungs, and lymph nodes in mice.Formal Name:...
| Keywords: | Ionizable Amphiphilic Janus Dendrimer 93, 3-((2-ethylhexyl)oxy)-2,2-bis(((2-ethylhexyl)oxy)methyl)propyl... |
| Application: | Ionizable amphiphilic Janus dendrimer mRNA delivery system, dendrimersome nanoparticle formation |
| MW: | 671 D |
From 281.00€
*
IAJD249
Item number: Cay39689-10
IAJD249 is an ionizable amphiphilic Janus dendrimer (IAJD) delivery system for mRNA (pKa = 6.35). It co-assembles with mRNA to form dendrimersome nanoparticles (DNPs) in acetate buffer. IAJD249 co-assembled with luciferase mRNA delivers the mRNA to the spleen, liver, lungs, and lymph nodes in mice.Formal Name:...
| Keywords: | Ionizable Amphiphilic Janus Dendrimer 249, 3-(octyloxy)-2,2-bis((octyloxy)methyl)propyl... |
| Application: | Ionizable amphiphilic Janus dendrimer mRNA delivery system, dendrimersome nanoparticle formation |
| MW: | 671 D |
From 186.00€
*
Lipid 331
Item number: Cay39771-1
Lipid 331 is a biodegradable cyclic ionizable cationic lipid (pKa = 7.53) that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing lipid 331 and encapsulating 5-methoxyuridine-modified mRNA encoding ovalbumin induce IFN regulatory factor (IRF)...
| Keywords: | di((9Z,12Z)-octadeca-9,12-dien-1-yl)... |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 978.5 D |
From 186.00€
*
Ganoderenic Acid D
Item number: Cay39774-1
Ganoderenic acid D is a triterpenoid originally isolated from G. lucidum and has diverse biological activities. It inhibits angiotensin-converting enzyme (ACE, IC50 = 734 µM). Ganoderenic acid D is cytotoxic to HepG2 liver, HeLa cervical, and Caco-2 colon cancer cells (IC50s = 0.14, 0.18, and 0.26 mg/ml,...
| Keywords: | (7beta,20E)-7-hydroxy-3,11,15,23-tetraoxo-lanosta-8,20(22)-dien-26-oic acid |
| Application: | Bioactive triterpenoid |
| CAS | 100665-43-8 |
| MW: | 512.6 D |
From 103.00€
*
Ganodermanondiol
Item number: Cay39776-1
Ganodermanondiol is a triterpenoid that has been found in G. lucidum and has diverse biological activities. It inhibits the proliferation of Meth A sarcoma and LLC1 lung carcinoma cells (IC50s = 3.4 and 12.5 µg/ml, respectively). Ganodermanondiol (20 µM) reduces the viability of RAW 264.7 macrophages. It inhibits...
| Keywords: | 24S,25-dihydroxy-lanosta-7,9(11)-dien-3-one |
| Application: | Bioactive triterpenoid |
| CAS | 107900-76-5 |
| MW: | 456.7 D |
From 83.00€
*
Benzydamine (hydrochloride)
Item number: Cay39808-10
Benzydamine is a non-steroidal anti-inflammatory drug (NSAID). It decreases the viability of THP-1 monocytes, Saos-2 osteosarcoma, and HGF-1 gingival cancer cells (IC50s = 59.08, 30.79, and 52.06 µg/ml, respectively). Benzydamine (10 µg/ml) reduces LPS-induced increases in the levels of IL-6 and TNF-alpha secreted...
| Keywords: | N,N-dimethyl-3-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-1-propanamine, monohydrochloride |
| Application: | NSAID, COX inhibitor |
| CAS | 132-69-4 |
| MW: | 345.9 D |
From 44.00€
*
5,7,3',4',5'-Pentamethoxyflavone
Item number: Cay39820-10
5,7,3',4',5'-Pentamethoxyflavone is a flavonoid that has been found in M. paniculata and has diverse biological activities. It inhibits pancreatic lipase in a cell-free assay and reduces lipid accumulation in 3T3-L1 adipocytes in a concentration-dependent manner. 5,7,3',4',5'-Pentamethoxyflavone inhibits...
| Keywords: | 3',4',5',5,7-Pentamethoxyflavone, 5,7,3',4',5'-PMF, 5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one |
| Application: | Bioactive flavonoid |
| CAS | 53350-26-8 |
| MW: | 372.4 D |
From 68.00€
*