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6-trans Leukotriene B4
Item number: Cay35250-25
6-trans LTB4 is produced by the non-enzymatic hydrolysis of LTA4. Oxidative decomposition of cysteinyl-leukotrienes such as LTC4 in the presence of myeloperoxidase and hypochlorous acid can also produce 6-trans LTB4, but the physiologic importance of this mechanism is not clear. 6-trans LTB4 is relatively inactive...
| Keywords: | 5(S),12(R)-DiHETE, 6-trans LTB4, all-trans LTB4, 5S,12R-dihydroxy-6E,8E,10E,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 71652-82-9 |
| MW: | 336.5 D |
From 215.00€
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12(S)-HpETE
Item number: Cay44570-25
12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It activates human blood leukocyte 5-LO, resulting in the synthesis of 5(S)-HETE, leukotriene B4 (LTB4), and 5(S),12(S)-DiHETE. Rat lung metabolizes...
| Keywords: | 12S-hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 71774-10-2 |
| MW: | 336.5 D |
From 196.00€
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MEL-A
Item number: Cay33858-25
MEL-A is a glycolipid biosurfactant that is produced from vegetable oils by Pseudozyma yeasts. Mixtures of MEL-A isoforms have been used as moisturizing agents in cosmetics, as well as to improve the low-temperature fluidity of biodiesel and hydrocarbon fuels. This product is a mixture of MEL-A isoforms with...
| Keywords: | Mannosylerythritol Lipid A,... |
| Application: | Glycolipid biosurfactant |
547.00€
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Kdo2-Lipid A (ready-to-use)
Item number: AG-CU1-0001-M001
Defined substructure of the Re mutant of lipopolysaccharide (LPS), Endotoxin activity equal to Re LPS, Strong activator (<10ng/ml) of macrophages via toll-like receptor 4 (TLR4), Does not activate TLR2 or other TLRs as determined with splenocytes and macrophages from TLR4 deficient mice by IL-6 ELISA, Facilitates...
| Keywords: | (3-Deoxy-D-manno-octulosonic acid)2-Lipid A, TLR4, CD284, hToll, Toll-like receptor 4 activation |
| Application: | TLR4 activator |
| MW: | 2326,7 D |
143.00€
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(+)-Cloprostenol isopropyl ester
Item number: Cay10010016-10
(+)-Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent...
| Keywords: | (+)-16-m-chlorophenoxy tetranor Prostaglandin F2alpha isopropyl ester, (+)-5-cis Cloprostenol isopropyl ester,... |
| Application: | FP receptor agonist |
| CAS | 157283-66-4 |
| MW: | 467 D |
From 108.00€
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PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
Item number: Cay64920-1
The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH)...
| Keywords: | DPPI-3,4,5-P3, Phosphatidylinositol-3,4,5-triphosphate C-16, D-myo-inositol 1-[(2R)-2,3-bis[(1-oxohexadecyl)oxy]propyl... |
| Application: | Bioactive lipid assays |
| CAS | 1628353-02-5 |
| MW: | 1138.9 D |
From 73.00€
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Lipid-based Drug Delivery Tools
1-Palmitoyl-2-Oleoyl-sn-glycero-3-PC
Item number: Cay15102-100
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (1,2-POPC) is a phospholipid containing 16:0 and 18:1 fatty acids at the sn-1 and sn-2 positions, respectively. It belongs to a class of phospholipids that are a major component of biological membranes. This compound can be used for liposome production in order to study the...
| Keywords: | 1,2-POPC, 1-Palmitoyl-2-Oleoyl-sn-glycero-3-Phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine |
| Application: | Liposome production |
| CAS | 26853-31-6 |
| MW: | 760.1 D |
From 114.00€
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13(S)-HpODE
Item number: Cay48610-100
13(S)-HpODE is produced by the oxidation of linoleic acid by lipoxygenase-1 (LO-1) in many plants including soybean, flaxseed, apples, and tea leaves, and by 15-LO in mammals. In plants, 13(S)-HpODE is the preferred substrate for the garlic bulb divinyl ether synthase. In mammalian tissues, 13(S)-HpODE is generally...
| Keywords: | 13S-hydroperoxy-9Z,11E-octadecadienoic acid |
| Application: | Bioactive lipid studies |
| CAS | 33964-75-9 |
| MW: | 312.4 D |
From 97.00€
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Hydrocortisone
Item number: Cay20739-1
Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor, with an approximately 6- to 10-fold greater affinity for MR....
| Keywords: | Cortisol, Dihydrocostisone, NSC 10483, (11beta)-11,17,21-trihydroxy-pregn-4-ene-3,20-dione |
| Application: | Natural glucocorticoid |
| CAS | 50-23-7 |
| MW: | 362.5 D |
From 45.00€
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9(Z),11(E)-Conjugated Linoleic Acid
Item number: Cay90140-10
9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) that has been found in beef and milk fat. It binds to peroxisome proliferator-activated receptor alpha (PPARalpha, IC50 = 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse...
| Keywords: | cis-9,trans-11-Conjugated Linoleic Acid, 9Z,11E-CLA, 9Z,11E-octadecadienoic acid |
| Application: | Bioactive lipid assays |
| CAS | 2540-56-9 |
| MW: | 280.5 D |
From 128.00€
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11-dehydro Thromboxane B2-d4
Item number: Cay319500-25
11-dehydro Thromboxane B2-d4 (TXB2-d4) is intended for use as an internal standard for the quantification of 11-dehydro TXB2 (Cay-19500) by stable isotope dilution MS. TXB2 is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2....
| Keywords: | 11-keto TXB2-d4, 11-dehydro TXB2-d4, 9alpha,15S-dihydroxy-11-oxothromba-5Z,13E-dien-1-oic-3,3,4,4-d4 acid |
| Application: | Standard |
| CAS | 1240398-15-5 |
| MW: | 372.5 D |
From 271.00€
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Methyl-beta-cyclodextrin
Item number: Cay21633-5
Methyl-beta-cyclodextrin is a randomly methylated form of the cyclic oligosaccharide beta-cyclodextrin (Cay-23387). Methyl-beta-cyclodextrin contains seven D-(+)-glucopyranose units that contain randomized hydrogen or methyl groups. Methyl-beta-cyclodextrin has been used to improve the aqueous solubility of various...
| Keywords: | Randomly methylated beta-cyclodextrin, beta-cyclodextrin, methyl ethers |
| Application: | Solubility enhancer |
| CAS | 128446-36-6 |
From 62.00€
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