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FAHFA 18:1(9Z)/32-O-32:1(25Z)
Item number: Cay37879-1
FAHFA 18:1(9Z)/32-O-32:1(25Z) is an (O-acyl)-omega-hydroxy fatty acid (OAHFA) containing the monounsaturated fatty acid oleic acid (Cay-90260, Cay-24659) and the very long-chain omega -hydroxy fatty acid 25(Z)-dotriacontenoic acid.Formal Name: (Z)-32-(oleoyloxy)dotriacont-25-enoic acid. Synonyms: OAHFA 18:1(n-9,...
| Keywords: | OAHFA 18:1(n-9, cis)/omega-O-32:1(n-7, cis), (Z)-32-(oleoyloxy)dotriacont-25-enoic acid |
| Application: | (O-acyl)-omega-hydroxy fatty acid (OAHFA) |
| MW: | 759.3 D |
From 251.00€
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4-Hydroxyphenylglyoxylic Acid
Item number: Cay38121-10
4-Hydroxyphenylglyoxylic acid is an inhibitor of carnitine palmitoyltransferase 1 (CPT1) and an active metabolite of the prodrug oxfenicine (Cay-33698). It inhibits CPT1 in isolated rat liver mitochondria when used at concentrations ranging from 200 to 1,000 µM and inhibits oleate oxidation in isolated rat...
| Keywords: | UK 22486, 4-hydroxy-alpha-oxo-benzeneacetic acid |
| Application: | Oxfenicine active metabolite, CPT1 inhibitor |
| CAS | 15573-67-8 |
| MW: | 166.1 D |
From 62.00€
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1,2-Diheptadecanoyl-sn-glycero-3-PE
Item number: Cay38319-10
1,2-Diheptadecanoyl-sn-glycero-3-PE is a glycerophospholipid containing heptadecanoic acid (Cay-19722) at the sn-1 and sn-2 positions. It has been used as an internal standard for the detection of phosphatidylethanolamines in human adipose tissue.Formal Name: heptadecanoic acid,...
| Keywords: | 1,2-Heptadecyloyl-sn-glycero-3-Phosphatidylethanolamine, 1,2-Heptadecyloyl-sn-glycero-3-Phosphoethanolamine, 17:0/17:0-PE,... |
| Application: | Glycerophospholipid |
| CAS | 140219-78-9 |
| MW: | 720 D |
From 91.00€
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AR-9281
Item number: Cay38346-10
AR-9281 is an inhibitor of soluble epoxide hydrolase (sEH, IC50 = 7 nM for the human enzyme). It reduces LPS-induced increases in plasma levels of dihydroxyeicosatrienoic acids (DiHETs), prostaglandin E2 (PGE2, Cay-14010), and PGD2 (Cay-12010) in rats when administered at a dose of 3 mg/kg. AR-9281 (1 and 3 mg/kg)...
| Keywords: | APAU, UC1153, N-(1-acetyl-4-piperidinyl)-N'-tricyclo[3.3.1.13,7]dec-1-yl-urea |
| Application: | Soluble epoxide hydrolase (sEH) inhibitor |
| CAS | 913548-29-5 |
| MW: | 319.4 D |
From 104.00€
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Lipid 10
Item number: Cay38705-10
Lipid 10 is an ionizable cationic lipid (pKa = 6.2-6.5). Lipid nanoparticles (LNPs) containing lipid 10 and encapsulating siRNA for the gene encoding cytoskeleton-associated protein 5 (CKAP5) reduce its gene expression and protein levels in vitro and selectively reduce cell viability in a variety of genetically...
| Keywords: | EA-PIP, 4-methyl-1-piperazinepropanoic acid, 2-[di-(9Z,12Z)-9,12-octadecadien-1-ylamino]ethyl ester |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2430034-02-7 |
| MW: | 712.2 D |
From 153.00€
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C12-SPM
Item number: Cay38784-10
C12-SPM is a polyamine branched-chain lipidoid. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of siRNA targeting the host protein kinase protein kinase C-related kinase 2 (PRK2) to inhibit hepatitis C virus (HCV) replication in Huh7 cells and a...
| Keywords: | C12-Spermine, 13,17,22,26-tetrakis(2-hydroxydodecyl)-13,17,22,26-tetraazaoctatriacontane-11,28-diol |
| Application: | Polyamine branched-chain lipidoid, LNP formation |
| CAS | 2055647-81-7 |
| MW: | 1308.3 D |
From 157.00€
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Beclomethasone Dipropionate
Item number: Cay38880-250
Beclomethasone dipropionate is a glucocorticoid receptor agonist and prodrug form of beclomethasone 17-propionate (Cay-38884). Beclomethasone dipropionate is converted to beclomethasone 17-propionate or beclomethasone 21-propionate via esterases, which are subsequently hydrolyzed to beclomethasone (Cay-33196). It...
| Keywords: | BC-DP, BDP, Beclomethasone 17,21-dipropionate,... |
| Application: | Beclomethasone 17-propionate prodrug, glucocorticoid receptor agonist |
| CAS | 5534-09-8 |
| MW: | 521 D |
From 110.00€
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Beclomethasone 17-Propionate
Item number: Cay38884-1
Beclomethasone 17-propionate is a glucocorticoid receptor agonist and an active metabolite of the glucocorticoid prodrug beclomethasone dipropionate (Cay-38880). It is formed from beclomethasone dipropionate via esterases and is subsequently hydrolyzed to beclomethasone (Cay-33196). Beclomethasone 17-propionate...
| Keywords: | 17-BMP, Beclometasone 17-Propionate, Beclomethasone 17-Monopropionate,... |
| Application: | Beclomethasone dipropionate active metabolite, glucocorticoid receptor agonist |
| CAS | 5534-18-9 |
| MW: | 465 D |
From 181.00€
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1,2-Dipalmitoyl-3-trimethylammoniumpropane (chloride)
Item number: Cay38907-10
DPTAP is a cationic lipid that has been used as a transfection reagent in vitro and in vivo and in the formation of liposomes and microbubbles. Microbubbles containing DPTAP and encapsulating the microRNA (miRNA) miR-145 reduce atherosclerotic plaque area by 48.04% using ultrasound-targeted microbubble destruction...
| Keywords: | 16:0 TAP, DPTAP, N,N,N-trimethyl-2,3-bis[(1-oxohexadecyl)oxy]-1-propanaminium, monochloride |
| Application: | Cationic lipid, liposome formation, transfection reagent |
| CAS | 139984-36-4 |
| MW: | 646.5 D |
From 78.00€
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Lipid AX4
Item number: Cay39070-10
Lipid AX4 is an ionizable cationic lipid (pKa = 6.89) that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. Administration of LNPs containing lipid AX4 and encapsulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant mRNA encoding the...
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2735814-23-8 |
| MW: | 1451.2 D |
From 235.00€
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(R)-2-(3-(2-Ethoxyphenoxy)piperidin-1-yl)pyrimidine-5-car...
Item number: Cay39257-1
(R)-2-(3-(2-Ethoxyphenoxy)piperidin-1-yl)pyrimidine-5-carboxylic acid is an intermediate in the synthesis of the diacylglycerol acyltransferase 2 (DGAT-2) inhibitor ervogastat (Cay-37929).Formal Name: 2-[(3R)-3-(2-ethoxyphenoxy)-1-piperidinyl]-5-pyrimidinecarboxylic acid. CAS Number: 1809064-89-8. Molecular Formula:...
| Keywords: | 2-[(3R)-3-(2-ethoxyphenoxy)-1-piperidinyl]-5-pyrimidinecarboxylic acid |
| Application: | Ervogastat synthesis intermediate |
| CAS | 1809064-89-8 |
| MW: | 343.4 D |
From 78.00€
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C12-113
Item number: Cay39335-10
C12-113 is an ionizable cationic lipidoid. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA encoding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein in mice.Formal Name:...
| Keywords: | 1,1',1'',1'''-[(methylimino)bis(2,1-ethanediylnitrilo)]tetrakis-2-dodecanol |
| Application: | Ionizable cationic lipidoid, LNP formation |
| CAS | 1220890-27-6 |
| MW: | 854.5 D |
From 157.00€
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