Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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Sphingosine-1-phosphate (d18:1(14Z))
Sphingosine-1-phosphate (d18:1(14Z))

Item number: Cay27020-1

Sphingosine-1-phosphate (d18:1(14Z)) is an atypical sphingolipid that contains a cis double bond at the 14-15 position rather than a trans double bond at the 4-5 position as in sphingosine-1-phosphate (d18:1) (Cay-62570).Formal Name: (2S,3R,Z)-2-amino-3-hydroxyoctadec-14-en-1-yl dihydrogen phosphate. Synonyms: S1P...
Keywords: S1P (d18:1(14Z)), (2S,3R,Z)-2-amino-3-hydroxyoctadec-14-en-1-yl dihydrogen phosphate
Application: Atypical sphingolipid
MW: 379.5 D
From 157.00€ *
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Myristic Acid-13C
Myristic Acid-13C

Item number: Cay29463-1

Myristic acid-13C is intended for use as an internal standard for the quantification of myristic acid (Cay-13351) by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of...
Keywords: C14:0-13C, tetradecanoic-1-13C acid
Application: GC-MS, LC-MS internal standard, quantification, N-myristoyltransferase substrate
CAS 57677-52-8
MW: 229.4 D
From 157.00€ *
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Dioctanoyl Glycol
Dioctanoyl Glycol

Item number: Cay31515-10

Dioctanoyl glycol is a diacylglycerol kinase (DGK) inhibitor (Ki = 58 µM). It reduces basal and thrombin-stimulated phosphatidic acid levels in washed isolated human platelets when used at concentrations of 30, 100, and 500 µM.Formal Name: octanoic acid, 1,1'-(1,2-ethanediyl) ester. CAS Number: 627-86-1. Synonyms:...
Keywords: 8:0 Ethylene Glycol, diC8-Ethylene Glycol, Dioctanoyl Glycol, Ethylene Glycol Dioctanoate, NSC 97300, octanoic acid,...
Application: DGK inhibitor
CAS 627-86-1
MW: 314.5 D
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(S)-Canadine
(S)-Canadine

Item number: Cay33805-1

(S)-Canadine is an alkaloid and intermediate in the biosynthesis of berberine (Cay-10006427) that has been found in H. canadensis.Formal Name: 5,8,13,13aS-tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine. CAS Number: 5096-57-1. Synonyms: (-)-Canadine, (S)-Tetrahydroberberine. Molecular...
Keywords: (-)-Canadine, (S)-Tetrahydroberberine, 5,8,13,13aS-tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine
Application: Alkaloid, insecticidal agent
CAS 5096-57-1
MW: 339.4 D
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Isoscopoletin
Isoscopoletin

Item number: Cay34117-10

Isoscopoletin is a coumarin that has been found in D. fragrans and has diverse biological activities and is an active metabolite of scoparone (Cay-20046). It is formed from scoparone by the cytochrome P450 (CYP) isoform Cyp2c29 in mouse liver microsomes. Isoscopoletin is cytotoxic to A549 lung, MCF-7 breast, and...
Keywords: 7-methoxy-6-Hydroxycoumarin, 7-Methoxyesculetin, Esculetin 7-methyl ether, 6-hydroxy-7-methoxy-2H-1-benzopyran-2-one
Application: Bioactive coumarin, active scoparone metabolite
CAS 776-86-3
MW: 192.2 D
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Farnesyl Alcohol
Farnesyl Alcohol

Item number: Cay13268-25

Farnesyl alcohol is an isoprenoid that has been found in aromatic plants and has diverse biological activities. It is an agonist of peroxisome proliferator-activator receptor alpha (PPARalpha) and PPARgamma (EC50s = 5.5 and 28 µM, respectively, in a reporter assay using CV-1 cells) and increases the expression of...
Keywords: Farnesol, FCI 119a, NSC 60597, 3,7,11-trimethyl-2,6,10-dodecatrien-1-ol
Application: Bioactive isoprenoid
CAS 4602-84-0
MW: 222.4 D
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Luteolin 7-O-Rutinoside
Luteolin 7-O-Rutinoside

Item number: Cay34035-1

Luteolin 7-O-rutinoside is a polyketide-derived flavonoid glycoside that has been found in V. bugulifolium and has diverse biological activities. It scavenges DPPH (Cay-14805) radicals in a cell-free assay when used at concentrations ranging from 1 to 50 µM. Luteolin 7-O-rutinoside is active against B. subtilis, S....
Keywords: Luteolin 7-Rutinoside, Luteolin 7-beta-Rutinoside, Scolymoside, Skolimoside,...
Application: Bioactive flavonoid glycoside
CAS 20633-84-5
MW: 594.5 D
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Dehydroepiandrosterone Sulfate 17-(O-carboxymethyl)oxime (sodium salt)
Dehydroepiandrosterone Sulfate 17-(O-carboxymethyl)oxime...

Item number: Cay35658-10

Dehydroepiandrosterone sulfate 17-(O-carboxymethyl)oxime is a derivative of dehydroepiandrosterone sulfate (Cay-15873).Formal Name: [[[(3beta)-3-(sulfooxy)androst-5-en-17-ylidene]amino]oxy]-acetic acid, monosodium salt. Synonyms: DHA-S 17-(O-carboxymethyl)oxime, DHEAS 17-(O-carboxymethyl)oxime. Molecular Formula:...
Keywords: DHA-S 17-(O-carboxymethyl)oxime, DHEAS 17-(O-carboxymethyl)oxime,...
Application: Dehydroepiandrosterone sulfate derivative
MW: 464.5 D
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Crebanine
Crebanine

Item number: Cay36176-1

Crebanine is an aporphine alkaloid that has been found in Stephania venosa and has diverse biological activities. It is an antagonist of alpha7 nicotinic acetylcholine receptors (nAChRs, IC50 = 19.1 µM) and inhibits sodium currents (INa) in isolated guinea pig ventricular myocytes (IC50 = 283 µM). Crebanine is...
Keywords: (-)-Crebanine, (7R)-6,7,7a,8-tetrahydro-9,10-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline
Application: Aporphine alkaloid
CAS 25127-29-1
MW: 339.4 D
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Lipid 14
Lipid 14

Item number: Cay38589-10

Lipid 14 is an ionizable cationic amino lipid that has been used in the formation of lipid nanoparticles (LNPs). LNPs containing lipid 14 and encapsulating mRNA encoding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein receptor-binding domain (RBD), also known as the surface...
Keywords: ((2-((4-(dimethylamino)butanoyl)oxy)ethyl)azanediyl)bis(octane-8,1-diyl) bis(2-hexyldecanoate)
Application: Ionizable cationic amino lipid, LNP formation
CAS 2430034-05-0
MW: 907.5 D
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1O14
1O14

Item number: Cay38150-10

1O14 is an ionizable cationic lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). 1O14-containing LNPs have been used for the delivery of IL-1beta siRNA to induce gene silencing and hepatoprotective effects in a mouse model of acute liver injury induced by LPS...
Keywords: 15,19,28-tris(2-hydroxytetradecyl)-15,19,24,28-tetraazadotetracontane-13,30-diol
Application: Ionizable cationic lipid, LNP formation
MW: 1264.2 D
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YK-009
YK-009

Item number: Cay38282-1

YK-009 is an ionizable cationic lipid (pKa = 6.512) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant mRNA in YK-009-containing LNPs induces the production of IgG that...
Keywords: 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]-hexanoic acid, 2-octyldecyl ester
Application: Ionizable cationic lipid, LNP formation
CAS 2761458-86-8
MW: 654.1 D
From 115.00€ *
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293 from 348 pages