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11-dehydro Thromboxane B2
Item number: Cay19500-50
Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. 11-dehydro TXB2 is one of the main plasma metabolites of TXB2 and can be used as a marker for in vivo TXA2 synthesis. The mean plasma level in human males...
| Keywords: | 11-dehydro TXB2, 11-keto TXB2, 9alpha,15S-dihydroxy-11-oxothromba-5Z,13E-dien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 67910-12-7 |
| MW: | 368.5 D |
From 161.00€
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12(S)-HEPE
Item number: Cay32550-25
12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for...
| Keywords: | 12S-hydroxy-5Z,8Z,10E,14Z,17Z-eicosapentaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 116180-17-7 |
| MW: | 318.5 D |
From 228.00€
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13(S)-HpOTrE
Item number: Cay45220-100
13(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced in soybeans by the action of soybean LO-2 on esterified alpha-linolenic acid. Incubation of soybean seedling biomembranes with soybean LO-2 catalyzes the formation of both 9- and 13-HpOTrE in a molar ratio of 10:1. In plants, 13(S)-HpOTrE can be...
| Keywords: | 13S-hydroperoxy-9Z,11E,15Z-octadecatrienoic acid |
| Application: | Bioactive lipid assays |
| CAS | 67597-26-6 |
| MW: | 310.4 D |
From 163.00€
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Leukotriene E4-d5
Item number: Cay10007858-25
Leukotriene E4-d5 (LTE4-d5) contains five deuterium atoms at the 19, 19', 20, 20 and 20 positions. It is intended for use as an internal standard for the quantification of LTE4 by GC- or LC-mass spectrometry. LTE4 is produced by the action of dipeptidase on LTD4, leaving only the cysteinyl group still attached to...
| Keywords: | LTE4-d5, 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic-19,19,20,20,20-d5 acid |
| Application: | Standard |
| CAS | 1240398-14-4 |
| MW: | 444.6 D |
From 433.00€
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Lipoxin B4
Item number: Cay90420-25
Lipoxin B4 (LXB4) is a positional isomer of LXA4 (Cay-90410) produced by the metabolism of 15-HETE (Cay-34700) or 15(S)-HpETE (Cay-44720) by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 (LTB4, Cay-20110) and inhibits...
| Keywords: | LXB4, 5S,14R,15S-trihydroxy-6E,8Z,10E,12E-eicosatetraenoic acid |
| Application: | Bioactive lipid studies |
| CAS | 98049-69-5 |
| MW: | 352.5 D |
From 407.00€
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11(Z)-Vaccenyl Acetate
Item number: Cay10010101-5
The mating and social behaviors of insects are largely orchestrated by a suite of volatile hydrocarbon pheromones. 11(Z)-Vaccenyl Acetate is the male-specific mating pheromone of the fruit fly D. melanogaster. It acts selectively through the Or67d odorant receptor to control mating behavior in both male and female...
| Keywords: | (11Z)-11-octadecen-1-ol, acetate |
| Application: | Mating pheromone |
| CAS | 6186-98-7 |
| MW: | 310.5 D |
From 36.00€
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(±)10-HDHA
Item number: Cay33400-25
(±)10-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)10-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.Formal Name:...
| Keywords: | (±)10-HDoHE, 10-hydroxy Docosahexaenoic Acid, (±)10-hydroxy-4Z,7Z,11E,13Z,16Z,19Z-docosahexaenoic acid |
| Application: | Oxidative stress marker |
| CAS | 90780-50-0 |
| MW: | 344.5 D |
From 115.00€
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Oleoyl Ethanolamide-d4
Item number: Cay9000552-100
Oleoyl ethanolamide-d4 contains four deuterium atoms at the hydroxyethyl 1,1',2, and 2' positions. It is intended for use as an internal standard for the quantification of oleoyl ethanolamide by GC- or LC-mass spectrometry. Oleoyl ethanolamide (OEA) is an analog of the endocannabinoid AEA found in brain tissue and...
| Keywords: | OEA-d4, Oleic Acid Ethanolamide-d4, N-(2-hydroxyethyl-1',1,2,2'-d4)-9Z-octadecenamide |
| Application: | Standard |
| CAS | 946524-36-3 |
| MW: | 329.6 D |
From 57.00€
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9-Nitrooleate
Item number: Cay10008042-1
Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate (LNO2, Cay-10037), cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules. LNO2 isomers serve as potent endogenous ligands for PPARgamma and can also decompose or be metabolized...
| Keywords: | 9-nitro-9-trans-Octadecenoic Acid, 9-Nitrooleic Acid, 9-nitro-9E-octadecenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 875685-44-2 |
| MW: | 327.5 D |
From 44.00€
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Ganglioside GD1a . disodium salt (bovine brain)
Item number: AG-CN2-9003-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Keywords: | GD1a . 2Na, Disialoganglioside GD1a . 2Na |
| Application: | Acidic glycosphingolipid |
| CAS | 12707-58-3 |
| MW: | 1836,1 D |
From 110.00€
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(S)-Bromoenol lactone
Item number: Cay10006801-1
The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent phospholipases (iPLA2) are a PLA2 subfamily closely associated with the release of arachidonic acid in response to physiologic stimuli....
| Keywords: | (S)-BEL, 6E-(bromoethylene)tetrahydro-3S-(1-naphthalenyl)-2H-pyran-2-one |
| Application: | iPLA2beta inhibitor |
| CAS | 478288-94-7 |
| MW: | 317.2 D |
From 49.00€
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L-161,982
Item number: Cay10011565-1
Prostaglandin E2 (PGE2) exerts its effects through four separate G coupled-protein receptors (EP1-4). L-161,982 is a potent and selective EP4 receptor antagonist. It demonstrates selective binding to human EP4 receptors with a Ki value of 0.024 µM compared to other receptors of the prostanoid family, EP1, EP2, EP3,...
| Keywords: | N-[[4'-[[3-butyl-1,5-dihydro-5-oxo-1-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl]methyl][1,1'-biphenyl]-2-yl]sulfony... |
| Application: | EP4 receptor antagonist |
| CAS | 147776-06-5 |
| MW: | 654.7 D |
From 56.00€
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