No results were found for the filter!
C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)
Item number: Cay24879-1
C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide (Cay-24870, Cay-24871, Cay-24872) that contains an adamantanyl group in place of the fatty acyl chain. It inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay when used at a...
| Keywords: | AdaGb3, Adamantyl Gb3, C2 Adamantanyl Ceramide Trihexoside (d18:1/2:0),... |
| Application: | Bioactive sphingolipid |
| CAS | 261155-87-7 |
| MW: | 962.17 D |
631.00€
*
Aranidipine
Item number: Cay40813-10
Aranidipine is an antagonist of voltage-gated calcium channel Cav3.2. It inhibits inward currents in Xenopus oocytes expressing human Cav3.2 channels when used at a concentration of 10 µM. Aranidipine (10 mg/kg) decreases mean blood pressure and increases heart rate in spontaneously hypertensive rats (SHRs). It...
| Keywords: | MPC-1304, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-yridinedicarboxylic acid, 3-methyl 5-(2-oxopropyl) ester |
| Application: | Cav3.2 antagonist |
| CAS | 86780-90-7 |
| MW: | 388.4 D |
From 73.00€
*
Pseudoginsenoside RT5
Item number: Cay42388-1
Pseudoginsenoside RT5 is an ocotillol-type ginsenoside that has been found in P. quinquefolium. SMILES C[C@]12[C@]3([C@@]([C@@H](C[C@]1([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])[C@H](C2)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO)C)O)([H])[C@]([C@]6(O[C@H](CC6)C(C)(O)C)C)([H])CC3)C InChi Code...
| Keywords: | 24(R)-Pseudoginsenoside RT5, Ginsenoside RT-5, (3beta,6alpha,12beta,24R)-20,24-epoxy-3,12,25-trihydroxydammaran-6-yl,... |
| Application: | Ginsenoside |
| CAS | 98474-78-3 |
| MW: | 654.87 D |
From 56.00€
*
Grayanotoxin I
Item number: Cay42644-100
Grayanotoxin I is a diterpene toxin that has been found in R. ponticum nectar, a component of mad honey. It increases resting sodium permeability in squid axonal membranes when used at a concentration of 10 µM. Grayanotoxin I (0.25, 0.5, and 1 mg/kg) induces proteinuria and reduces serum levels of alanine...
| Keywords: | Acetylandromedol, Andromedotoxin, Asebotoxin, GTX I, NSC 26711, Rhodotoxin, grayanotoxane-3beta,5,6beta,10,14R,16-hexol,... |
| Application: | Diterpene toxin, reversible Nav1.x agonist |
| CAS | 4720-09-6 |
| MW: | 412.52 D |
From 186.00€
*
Androst-5-enediol Sulfate (sodium salt)
Item number: Cay43450-1
Androst-5-enediol sulfate is a metabolite of 5-androstenediol. SMILES C[C@]12C(C[C@@H](OS([O-])(=O)=O)CC2)=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4O.[Na+] InChi Code...
| Keywords: | 5-Androstenediol 3-sulfate, androst-5-ene-3beta,17beta-diol, 3-(hydrogen sulfate), monosodium salt |
| Application: | 5-Androstenediol metabolite |
| CAS | 131211-33-1 |
| MW: | 392.49 D |
From 142.00€
*
Pregnanolone
Item number: Cay42751-1
Pregnanolone is a neurosteroid and an active metabolite of pregnenolone (Cay19864). It is formed from pregnenolone via the intermediates progesterone (Cay15876) and 5beta-dihydroprogesterone (Cay34644). Pregnanolone enhances the binding of flunitrazepam to GABAA receptors in rat brain homogenate (EC50 = 237 nM) and...
| Keywords: | 3alpha,5beta-P, 3alpha,5beta-Tetrahydroprogesterone, 5beta-Pregnan-3alpha-ol-20-one, Eltanolone, NSC 82867, SKF 6455,... |
| Application: | Pregnenolone active metabolite, neurosteroid |
| CAS | 128-20-1 |
| MW: | 318.5 D |
From 49.00€
*
5beta-Cholanic Acid-3,7-dione
Item number: Cay43575-1
5beta-Cholanic acid-3,7-dione is a synthetic bile acid. It decreases bile volume and bile levels of cholic acid and cholesterol in rabbits when administered at a dose of 5 mg/kg. SMILES C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](CC(CC4)=O)([H])CC3=O)C InChi Code...
| Keywords: | 3,7-Diketochenodeoxycholic Acid, 3,7-Dioxo-5beta-cholan-24-oic Acid, Dehydrochenodeoxycholic Acid,... |
| Application: | Synthetic bile acid |
| CAS | 859-97-2 |
| MW: | 388.55 D |
From 44.00€
*
Montelukast (sodium salt)
Item number: Cay10008318-10
Montelukast is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 4.9 nM in HEK293 cell membranes expressing the human receptor). It is selective for CysLT1 over CysLT2 receptors (IC50 = >10,000 nM in COS-7 cell membranes expressing the human receptor). Montelukast inhibits bronchoconstriction induced by...
| Keywords: | MK-476,... |
| Application: | CysLT1 receptor antagonist |
| CAS | 151767-02-1 |
| MW: | 608.2 D |
From 29.00€
*
(±)14(15)-DiHETE
Item number: Cay10006998-25
(±)14(15)-DiHETE is an oxylipin and a metabolite of the omega-3 fatty acid eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). It is formed via cytochrome P450-mediated epoxidation of EPA to (±)14(15)-EpETE (Cay-10173), followed by conversion of the epoxide to a diol by soluble epoxide hydrolase.Formal...
| Keywords: | (±)14,15-dihydroxy-eicosa-5,8,11,17-Tetraenoic Acid, (±)14,15-dihydroxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| MW: | 336.5 D |
From 157.00€
*
Lipid-based Drug Delivery Tools
C16 Sphingomyelin (d18:1/16:0)
Item number: Cay10007946-1
C16 Sphingomyelin is a naturally occurring sphingolipid. Levels of C16 sphingomyelin are elevated in the prefrontal cortex and cerebellum in a rat model of diabetes induced by streptozotocin (STZ, Cay-13104), as well as in the liver in mouse models of Niemann-Pick type C1 disease. Plasma levels of C16 sphingomyelin...
| Keywords: | N-Palmitoyl-D-erythro-Sphingosylphosphorylcholine, Palmitoyl Sphingomyelin, SM(d18:1/16:0), Sphingomyelin (d18:1/16:0),... |
| Application: | Bioactive Lipid Assays |
| CAS | 6254-89-3 |
| MW: | 703 D |
From 112.00€
*
(±)9(10)-DiHOME-d4
Item number: Cay10009993-25
(±)9(10)-DiHOME-d4 is intended for use as an internal standard for the quantification of 9(10)-DiHOME by GC- or LC-MS. (±)9(10)-DiHOME is the diol form of (±)9(10)-EpOME (Cay-52400), a cytochrome P450-derived epoxide of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) also known as leukotoxin. It is formed from...
| Keywords: | Leukotoxin diol-d4, (±)9,10-dihydroxy-12Z-octadecenoic-9,10,12,13-d4 acid |
| Application: | Standard |
| MW: | 318.5 D |
From 112.00€
*
25(R)-27-hydroxy Cholesterol
Item number: Cay14790-1
The liver X receptors (LXRalpha and LXRbeta) are nuclear hormone receptors whose native ligands, oxysterols, induce the expression of genes involved in cholesterol and fatty acid metabolism. 27-hydroxy Cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRalpha and LXRbeta in...
| Keywords: | (25R)-26-hydroxy Cholesterol, (25R)-cholest-5-ene-3beta,26-diol |
| Application: | LXR alpha / beta activator |
| CAS | 20380-11-4 |
| MW: | 402.7 D |
From 85.00€
*