Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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Stearoyl Ethanolamide
Stearoyl Ethanolamide

Item number: Cay90245-5

Stearoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called anandamides. Stearoyl ethanolamide is the most abundant of several fatty acid ethanolamides produced by the PLD hydrolysis of mouse neuroblastoma cell membrane phospholipids. The specific role of stearoyl ethanolamide...
Keywords: Ceramid, Stearic Acid Ethanolamide, N-(2-hydroxyethyl)-octadecanamide
Application: Bioactive lipid assays
CAS 111-57-9
MW: 327.6 D
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Ganglioside GQ1b . tetrasodium salt (bovine brain)
Ganglioside GQ1b . tetrasodium salt (bovine brain)

Item number: AG-CN2-9007-C500

Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
Keywords: GQ1b . 4Na, Tetrasialoganglioside GQ1b . 4Na
Application: Acidic glycosphingolipid
CAS 68652-37-9
MW: 2416,6 D
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Lutein
Lutein

Item number: Cay10010811-1

Lutein is a dietary carotenoid that has been found in eggs and yellow-colored fruits and vegetables and has diverse biological activities. It reduces hyperglycemia-induced mitochondrial DNA damage and production of reactive oxygen species (ROS) and promotes mitochondrial biogenesis in ARPE-19 cells when used at a...
Keywords: E 161b, Xanthophyll, (6'R)-beta,epsilon-carotene-3R,3'R-diol
Application: Lipid-soluble antioxidant
CAS 127-40-2
MW: 568.9 D
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14(S)-HDHA
14(S)-HDHA

Item number: Cay15253-25

14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA, Cay-90310). It is a precursor to the pro-resolving mediator maresin 1 (Cay-10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis.Formal Name:...
Keywords: 14(S)-hydroxy Docosahexaenoic Acid, 14(S)-HDoHE, 14S-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid
Application: Oxidative stress marker
CAS 119433-37-3
MW: 344.5 D
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Linoleoyl Ethanolamide
Linoleoyl Ethanolamide

Item number: Cay90155-5

Linoleoyl ethanolamide is an endocannabinoid detected in porcine brain and murine peritoneal macrophages which contains linoleate in place of the arachidonate moiety of arachidonyl ethanolamide (AEA). It has weak affinity for the cannabinoid 1 (CB1) and CB2 receptors, exhibiting Ki values of 10 µM and 25 µM,...
Keywords: LEA, N-(2-hydroxyethyl)-9Z,12Z-octadecadienamide
Application: Bioactive lipid assays
CAS 68171-52-8
MW: 323.5 D
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(±)18-HETE
(±)18-HETE

Item number: Cay10010638-25

(±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. When formed by the CYP2E1 isoform, 18-HETE is comprised 100% of the (R) isomer. 18(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, whereas 18(S)-HETE does not affect perfusion pressure. 18-HETE has...
Keywords: (±)18-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 133268-58-3
MW: 320.5 D
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Chenodeoxycholic Acid
Chenodeoxycholic Acid

Item number: Cay10011286-1

Chenodeoxycholic acid (CDCA) is a hydrophobic primary bile acid. It is formed from cholesterol in the liver via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. CDCA is a farnesoid X receptor (FXR) agonist that binds to FXRs in a TR-FRET assay (EC50 = 13 µM) and...
Keywords: Anthropodeoxycholic Acid, CDCA, Fluibil, Hekbilin, Kebilis, Ulmenide, (3alpha,5beta,7alpha)-3,7-dihydroxy-cholan-24-oic acid
Application: Bioactive lipid assays
CAS 474-25-9
MW: 392.6 D
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9-PAHSA
9-PAHSA

Item number: Cay17037-5

Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to a...
Keywords: 9-[(1-oxohexadecyl)oxy]-octadecanoic acid
Application: Branched fatty acid ester of hydroxy fatty acid (FAHFA)
CAS 1481636-31-0
MW: 538.9 D
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9(S)-HOTrE
9(S)-HOTrE

Item number: Cay39420-100

9(S)-HOTrE is a monohydroxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase on alpha-linolenic acid. 9(S)-HOTrE is predominantly localized in cellular ester lipids of Glechoma hederacea leaves and is partially released during artificial dehydration. The biological role of 9(S)-HOTrE in G....
Keywords: 9S-hydroxy-10E,12Z,15Z-octadecatrienoic acid
Application: Bioactive lipid assays
CAS 89886-42-0
MW: 294.4 D
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2-Arachidonyl Glycerol ether
2-Arachidonyl Glycerol ether

Item number: Cay62165-1

2-Arachidonyl glycerol ether (2-AG ether) selectively binds to cannabinoid (CB) receptor 1 (Kis = 21.2 and >3,000 nM for CB1 and CB2, respectively, in a radioligand binding assay). It is a potent and selective agonist of CB1 and GPR55 with EC50 values of 10, 37, and >30,000 nM for CB1, GPR55, and CB2, respectively....
Keywords: 2-AG ether, Noladin, 5Z,8Z,11Z,14Z-eicosatetraen-2-glyceryl ether
Application: CB1 receptor agonist
CAS 222723-55-9
MW: 364.6 D
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DMG-PEG(2000)
DMG-PEG(2000)

Item number: Cay33945-500

DMG-PEG(2000) is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of fumarylacetoacetate hydrolase (FAH) mRNA in DMG-PEG(2000)-containing LNPs increases survival in a mouse model of hereditary tyrosinemia type 1 (HT-1). Formulations...
Keywords: 1,2-Dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000,...
Application: Lipid excipient
CAS 160743-62-4
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Docosahexaenoic Acid (peroxide free)
Docosahexaenoic Acid (peroxide free)

Item number: Cay17932-10

Docosahexaenoic acid (DHA) is a long-chain omega-3 polyunsaturated fatty acid (PUFA) found in fish and algal oils. It comprises approximately 40% of total brain PUFAs and is abundant in grey matter and retinal membranes. DHA typically represents 0.52-7.5% of human total plasma fatty acids. It is produced from...
Keywords: 4,7,10,13,16,19-Docosahexaenoic Acid, C22:6 n-3, C22:6(4Z,7Z,10Z,13Z,16Z,19Z), Cervonic Acid, DHA,...
Application: Long-chain omega-3 PUFA
CAS 6217-54-5
MW: 328.5 D
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