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Resolvin D3
Item number: Cay13834-10
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response. Resolvin D3 (RvD3) is a DHA-derived product first identified in...
| Keywords: | RvD3, 4S,11R,17S-trihydroxy-5Z,7E,9E,13Z,15E,19Z-docosahexaenoic acid |
| Application: | Antiinflammatory lipid mediator |
| CAS | 916888-47-6 |
| MW: | 376.5 D |
From 228.00€
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C8 Ceramide-1-phosphate (d18:1/8:0)
Item number: Cay62547-1
C8 ceramide-1-phosphate is a short-chain analog of the naturally occurring ceramide-1-phosphate. The effects of C8 ceramide-1-phosphate are essentially the opposite of C8 ceramide, it induces DNA synthesis and cell division. The effects of C8 ceramide-1-phosphate can be attenuated by simultaneous treatment with C2...
| Keywords: | C8 Ceramide-1-phosphate, Ceramide-1-phosphate (d18:1/8:0), CerP(d18:1/8:0), N-octanoyl-Ceramide-1-phosphate,... |
| Application: | Bioactive lipid assays |
| CAS | 158983-53-0 |
| MW: | 505.7 D |
From 147.00€
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Arachidonoyl Ethanolamide-d4
Item number: Cay10011178-500
Arachidonoyl ethanolamide-d4 (AEA-d4) contains four deuterium atoms at the hydroxyethyl 1,1',2, and 2' positions. It is intended for use as an internal standard for the quantification of AEA by GC- or LC-mass spectrometry. AEA is the ethanolamine amide of arachidonic acid, first isolated from porcine brain. It is an...
| Keywords: | AEA-d4, Anandamide-d4, N-(2-hydroxyethyl-1,1,2,2-d4)-5Z,8Z,11Z,14Z-eicosatetraenamide |
| Application: | Standard |
| CAS | 946524-40-9 |
| MW: | 351.6 D |
From 68.00€
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SEW2871
Item number: Cay10006440-10
Sphingosine-1-phosphate receptor 1 (S1P1) is one of five high affinity G protein-coupled S1P receptors which mediate a variety of effects including lymphocyte recirculation in the blood. Non-selective S1P receptor agonists, such as FTY720, produce clinical immunosuppression useful for preventing transplant rejection...
| Keywords: | 5-[4-phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole |
| Application: | S1P1 receptor agonist |
| CAS | 256414-75-2 |
| MW: | 440.4 D |
From 49.00€
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N-Oleoyl Dopamine
Item number: Cay10115-5
N-Oleoyl dopamine (ODA) is a selective, endogenous vanilloid receptor 1 (VR1) agonist isolated from bovine brain. Structurally, it is the amide of oleic acid and dopamine and is therefore a "hybrid" analog which incorporates components of both the anandamide-like and dopamine neurotransmitter pathways. ODA binds to...
| Keywords: | ODA, N-[2-(3,4-dihydroxyphenyl)ethyl]-9Z-octadecenamide |
| Application: | VR1 agonist |
| CAS | 105955-11-1 |
| MW: | 417.6 D |
From 67.00€
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11beta-Prostaglandin F2alpha
Item number: Cay16520-1
11beta-Prostaglandin F2alpha (11beta-PGF2alpha) is the primary metabolite of PGD2 (Cay-12010). It is formed from PGD2 via the NADPH-dependent aldo-keto reductase PGF synthase (PGFS, Cay-10007940) in the liver or lung. 11beta-PGF2alpha induces contraction of isolated cat iris sphincter, which endogenously expresses...
| Keywords: | 11-epi PGF2alpha, 11beta-PGF2alpha, 9alpha,11beta-PGF2alpha,... |
| Application: | Bioactive lipid assays |
| CAS | 38432-87-0 |
| MW: | 354.5 D |
From 208.00€
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all-trans Retinal
Item number: Cay18449-100
all-trans Retinal is a natural retinoid that is derived from vitamin A. It is the oxidation product of all-trans retinol and associates with cellular retinol-binding protein-I (CRBP-I) and CRBP-II (Kds = 50 and 90 nM, respectively), which are involved in the intracellular transport of retinol. all-trans Retinal is...
| Keywords: | Retinaldehyde, Vitamin A aldehyde, retinal |
| Application: | Natural retinoid |
| CAS | 116-31-4 |
| MW: | 284.4 D |
From 68.00€
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10(S)-hydroxy Stearic Acid
Item number: Cay44258-1
10(S)-hydroxy Stearic acid is a hydroxy fatty acid and minor metabolite of oleic acid (Cay90260, Cay24659) formed by gut microbiota and other bacteria. It inhibits the proliferation of A549 lung cancer and Caco-2 colon cancer cells when used at concentrations of 50 and 100 µM. SMILES CCCCCCCC[C@H](O)CCCCCCCCC(O)=O...
| Keywords: | 10(S)-HODA, 10(S)-HSA, 10(S)-hydroxy ODA, 10(S)-Hydroxyoctadecanoic Acid, FA 18:0,O, (S)-10-hydroxy-octadecanoic acid |
| Application: | Hydroxy fatty acid |
| CAS | 67042-09-5 |
| MW: | 300.48 D |
From 147.00€
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(±)17(18)-DiHETE
Item number: Cay10006999-25
Eicosapentaenoic acid (EPA, Cay-90110) is an omega-3 fatty acid abundantly available in marine organisms. (±)17(18)-DiHETE is one of the major metabolites produced when eicosapentaenoic acid (EPA) is incubated with various rat tissue homogenates or cynomolgus monkey seminal vesicles. The route of production of...
| Keywords: | (±)17,18-dihydroxy-eicosa-5,8,11,14-Tetraenoic Acid, (±)17,18-dihydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| MW: | 336.5 D |
From 157.00€
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19(S)-HETE
Item number: Cay10007766-25
19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators...
| Keywords: | 19S-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 115461-40-0 |
| MW: | 320.5 D |
From 217.00€
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15-deoxy-Delta12,14-Prostaglandin J2
Item number: Cay18570.1-1
This formulation of 15-deoxy-Delta12,14-PGJ2 contains 90-95% of the trans,trans-Delta12,14 isomer, and 5-10% of other double bond isomers which have similar PPARgamma ligand activity (see Catalog No. 18570).Formal Name: 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid. CAS Number: 87893-55-8. Synonyms:...
| Keywords: | 15-deoxy-Delta12,14-PGJ2, 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid |
| Application: | PPARgamma ligand |
| CAS | 87893-55-8 |
| MW: | 316.4 D |
From 110.00€
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Stearoyl Ethanolamide
Item number: Cay90245-5
Stearoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called anandamides. Stearoyl ethanolamide is the most abundant of several fatty acid ethanolamides produced by the PLD hydrolysis of mouse neuroblastoma cell membrane phospholipids. The specific role of stearoyl ethanolamide...
| Keywords: | Ceramid, Stearic Acid Ethanolamide, N-(2-hydroxyethyl)-octadecanamide |
| Application: | Bioactive lipid assays |
| CAS | 111-57-9 |
| MW: | 327.6 D |
From 93.00€
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