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(±)4-HDHA
Item number: Cay33200-25
(±)4-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Enzymatic transformation of DHA by RBL-1 cells also produces 4-HDHA. However, the enzymatic product is most likely the S-isomer. (±)4-HDHA is a...
| Keywords: | (±)4-HDoHE, 4-hydroxy Docosahexaenoic Acid, (±)4-hydroxy-5E,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid |
| Application: | Oxidative stress marker |
| CAS | 90906-40-4 |
| MW: | 344.5 D |
From 106.00€
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(±)5-HEPE
Item number: Cay32200-25
(±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine...
| Keywords: | (±)-5-hydroxy-6E,8Z,11Z,14Z,17Z-eicosapentaenoic acid |
| Application: | Bioactive lipid studies |
| CAS | 83952-40-3 |
| MW: | 318.5 D |
From 161.00€
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17(S)-HDHA
Item number: Cay10009799-50
17(S)-HDHA is a hydroxy fatty acid formed from docosahexaenoic acid (DHA, Cay-90310) by 15-lipoxygenase (15-LO) and is a precursor to 17(S)-resolvins. 17(S)-HDHA inhibits platelet 12-LO (IC50 = 0.4 µM). It inhibits TNF-alpha-induced expression of IL1B in a human glial cell line (IC50 = ~0.5 nM). 17(S)-HDHA (100 nM)...
| Keywords: | 17(S)-HDoHE, 17(S)-hydroxy Docosahexaenoic Acid, 17S-hydroxy-4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 92693-03-3 |
| MW: | 344.5 D |
From 96.00€
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Stearic Acid
Item number: Cay10011298-500
Stearic acid is a long-chain saturated fatty acid. It is a major component of cocoa butter and has also been found in beef fat and vegetable oils. Unlike many long-chain saturated fatty acids, dietary stearic acid does not induce hypercholesterolemia or raise LDL-cholesterol.Formal Name: octadecanoic acid. CAS...
| Keywords: | C18:0, Octadecanoic Acid, octadecanoic acid |
| Application: | Lipid assays |
| CAS | 57-11-4 |
| MW: | 284.5 D |
16.00€
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tetranor-PGDM
Item number: Cay12850-25
Prostaglandin D2 (PGD2, Cay-12010) is synthesized by hematopoietic-type PGD-synthase (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. PGD2 is also produced in the brain by lipocalin-PGD-synthase also known as beta-trace. In the brain, PGD2 produces normal...
| Keywords: | tetranor-PGD Metabolite, tetranor-Prosatglandin D Metabolite,... |
| Application: | Metabolic studies |
| CAS | 70803-91-7 |
| MW: | 328.4 D |
From 221.00€
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Bromoenol lactone
Item number: Cay70700-5
BEL is a selective, potent, irreversible, mechanism-based inhibitor of myocardial cytosolic calcium-independent phospholipase A2 (iPLA2) with a Ki value of 180 nM. BEL also inhibits macrophage iPLA2 in a concentration-dependent manner with an IC50 value of 60 nM and is an effective enzyme-activated irreversible...
| Keywords: | BEL, Haloenol lactone, HELSS, 6E-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one |
| Application: | iPLA2 inhibitor |
| CAS | 88070-98-8 |
| MW: | 317.2 D |
From 164.00€
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(±)14(15)-EpETE
Item number: Cay10173-25
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty...
| Keywords: | (±)14,15 EEQ, (±)14,15-epoxy Eicosatetraenoic Acid, (±)14,15-epoxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 131339-24-7 |
| MW: | 318.5 D |
From 66.00€
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Resolvin D3
Item number: Cay13834-10
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response. Resolvin D3 (RvD3) is a DHA-derived product first identified in...
| Keywords: | RvD3, 4S,11R,17S-trihydroxy-5Z,7E,9E,13Z,15E,19Z-docosahexaenoic acid |
| Application: | Antiinflammatory lipid mediator |
| CAS | 916888-47-6 |
| MW: | 376.5 D |
From 209.00€
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C8 Ceramide-1-phosphate (d18:1/8:0)
Item number: Cay62547-1
C8 ceramide-1-phosphate is a short-chain analog of the naturally occurring ceramide-1-phosphate. The effects of C8 ceramide-1-phosphate are essentially the opposite of C8 ceramide, it induces DNA synthesis and cell division. The effects of C8 ceramide-1-phosphate can be attenuated by simultaneous treatment with C2...
| Keywords: | C8 Ceramide-1-phosphate, Ceramide-1-phosphate (d18:1/8:0), CerP(d18:1/8:0), N-octanoyl-Ceramide-1-phosphate,... |
| Application: | Bioactive lipid assays |
| CAS | 158983-53-0 |
| MW: | 505.7 D |
From 130.00€
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(±)-Jasmonic Acid
Item number: Cay88300-100
(±)-Jasmonic acid is a plant growth regulator and a derivative of alpha-linolenic acid (Cay-90210, Cay-21910). It decreases chlorophyll levels in green and etiolated barley leaf segments when used at concentrations of 10 and 50 µM. (±)-Jasmonic acid (10-1,000 µM) inhibits elongation of rice seedlings. It increases...
| Keywords: | 3-oxo-2R-(2Z)2-penten-1R-yl-cyclopentaneacetic acid |
| Application: | Plant growth regulator |
| CAS | 77026-92-7 |
| MW: | 210.3 D |
From 58.00€
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Arachidonoyl Ethanolamide-d4
Item number: Cay10011178-500
Arachidonoyl ethanolamide-d4 (AEA-d4) contains four deuterium atoms at the hydroxyethyl 1,1',2, and 2' positions. It is intended for use as an internal standard for the quantification of AEA by GC- or LC-mass spectrometry. AEA is the ethanolamine amide of arachidonic acid, first isolated from porcine brain. It is an...
| Keywords: | AEA-d4, Anandamide-d4, N-(2-hydroxyethyl-1,1,2,2-d4)-5Z,8Z,11Z,14Z-eicosatetraenamide |
| Application: | Standard |
| CAS | 946524-40-9 |
| MW: | 351.6 D |
From 49.00€
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tetranor-PGEM-d6
Item number: Cay314840-25
tetranor-Prostaglandin E metabolite-d6 (tetranor-PGEM-d6) is intended for use as an internal standard for the quantification of tetranor-PGEM (Cay-14840) by GC- or LC-MS. tetranor-PGEM is the major urinary metabolite of PGE2 (Cay-14010). Urine levels of tetranor-PGEM are increased in patients with diabetic...
| Keywords: | tetranor-Prostaglandin E Metabolite-d6,... |
| Application: | Standard |
| CAS | 1240398-16-6 |
| MW: | 334.4 D |
From 365.00€
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