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4A3-SC10
Item number: Cay44320-1
4A3-SC10 is an ionizable cationic lipid (pKa = 6.57) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing 4A3-SC10 selectively accumulate in the liver, kidney, and spleen in mice. LNPs containing 4A3-SC10 and encapsulating an mRNA reporter...
| Keywords: | 4A3-SC-10 |
| Application: | Ionizable cationic lipid, LNP generation, in vitro/in vivo mRNA delivery |
| CAS | 1857340-80-7 |
| MW: | 1579.4 D |
From 68.00€
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10(S)-hydroxy Stearoyl Ethanolamide
Item number: Cay9004508-1
10(S)-hydroxy Stearoyl ethanolamide is a fatty amide. InChI: InChI=1S/C20H41NO3/c1-2-3-4-5-8-11-14-19(23)15-12-9-6-7-10-13-16-20(24)21-17-18-22/h19,22-23H,2-18H2,1H3,(H,21,24)/t19-/m0/s1 InChIKey: UUWUSZRXJDUQKH-IBGZPJMESA-N SMILES: O=C(NCCO)CCCCCCCC[C@@H](O)CCCCCCCC
| Keywords: | 10(S)-HSEA, 10(S)-hydroxy Octadecanoyl Ethanolamide, 10(S)-hydroxy Octadecanoyl-EA, 10(S)-hydroxy ODEA, 10(S)-hydroxy... |
| Application: | Fatty amide |
| MW: | 343.6 D |
From 146.00€
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N,N-ditetradecylamine-pSar50-acetyl
Item number: Cay44164-10
N,N-ditetradecylamine-pSar50-acetyl is an amine-functionalized hydrophilic polymer and a polysarcosine-conjugated form of ditetradecylamine. Polysarcosines (pSars) have been used as alternatives to PEGylated lipids in lipid nanoparticles (LNPs). Liposomes containing pSar exhibit similar physicochemical properties in...
| Keywords: | (C14)2-pSar50-acetyl, Dimyristylamine-pSar50-acetyl, N,N-ditetradecylamine-Polysarcosine50-acetyl,... |
| Application: | Amine-functionalized hydrophilic polymer, LNP use |
From 216.00€
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DMPE-pSar50-acetyl
Item number: Cay44165-10
DMPE-pSar50-acetyl is an amine-functionalized hydrophilic polymer and a polysarcosine-conjugated form of 1,2-dimyristoyl-sn-glycero-3-PE (1,2-DMPE, Cay-15090). Polysarcosines (pSars) have been used as alternatives to PEGylated lipids in lipid nanoparticles (LNPs). Liposomes containing pSar exhibit similar...
| Keywords: | 1,2-Dimyristoyl-sn-glycero-3-Phosphoethanolamine-Polysarcosine50-acetyl,... |
| Application: | Amine-functionalized hydrophilic polymer, LNP use |
From 216.00€
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DMPE-PSar50-H
Item number: Cay44168-1
DMPE-PSar50-H is an amine-functionalized hydrophilic polymer and a polysarcosine-conjugated form of 1,2-dimyristoyl-sn-glycero-3-PE (1,2-DMPE, Cay-15090). Polysarcosines (PSars) have been used as alternatives to PEGylated lipids in lipid nanoparticles (LNPs). Liposomes containing PSar exhibit similar physicochemical...
| Keywords: | 1,2-Dimyristoyl-sn-glycero-3-Phosphoethanolamine-Polysarcosine50,... |
| Application: | Amine-functionalized hydrophilic polymer, LNP use |
From 38.00€
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iPr-pSar20-succ-tocopherol
Item number: Cay44169-1
iPr-pSar20-succ-tocopherol is an amine-functionalized hydrophilic polymer and a polysarcosine-conjugated form of isopropylamine. Polysarcosines (pSars) have been used as alternatives to PEGylated lipids in lipid nanoparticles (LNPs). Liposomes containing pSar exhibit similar physicochemical properties in vitro to...
| Keywords: | Isopropylamine-Polysarcosine20-tocopherol succinate, pSar20-VitE, Tocopheryl-Polysarcosine succinate, TPSS,... |
| Application: | Amine-functionalized hydrophilic polymer, LNP use |
From 38.00€
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Tauro-beta-muricholic Acid (sodium salt)
Item number: Cay20289-1
Tauro-beta-muricholic acid (TbetaMCA) is a competitive and reversible antagonist of the farnesoid X receptor (FXR, IC50 = 40 µM) and a taurine-conjugated form of the murine-specific primary bile acid beta-muricholic acid (Cay-20287). TbetaMCA accumulates in germ-free mice under normal conditions but is reduced after...
| Keywords: | Tauro-beta-muricholate, TbetaMCA, 2-[[(3alpha,5beta,6beta,7beta)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic... |
| Application: | FXR antagonist |
| CAS | 145022-92-0 |
| MW: | 537.7 D |
From 116.00€
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1-Oleoyl-2-acetyl-sn-glycerol
Item number: Cay62600-10
OAG is a cell-permeable analog of the PKC-activating second messenger DAG. It activates PKC in platelets, resulting in the phosphorylation of a 40 kDa protein. OAG is metabolized to its corresponding phosphatidic acid (1-oleoyl-2-acetyl-3-phosphoglycerol), most likely through the action of a diglycerol kinase.Formal...
| Keywords: | OAG, 1-O-9Z-octadecenoyl-2-O-acetyl-sn-glycerol |
| Application: | Bioactive lipid assays |
| CAS | 86390-77-4 |
| MW: | 398.6 D |
From 85.00€
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Arachidonoyl Glycine-d8
Item number: Cay10007531-100
Arachidonoyl glycine-d8 (NAGly-d8) contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of NAGly by GC- or LC-mass spectrometry. NAGly has been isolated from cell cultures treated with arachidonoyl ethanolamide (AEA),...
| Keywords: | N-Arachidonyl Glycine-d8, NAGly-d8, N-[1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl]-glycine,5,6,8,9,11,12,14,15-d8 |
| Application: | Standard |
| CAS | 1159908-44-7 |
| MW: | 369.6 D |
From 56.00€
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Fumonisin B2
Item number: Cay13227-1
Fumonisin B2 (FB2) is a mycotoxin that has been found in F. moniliforme. It is cytotoxic against a panel of seven rat hepatoma cell lines (IC50s = 3-50 µg/ml), as well as MDCK cells (IC50 = 2 µg/ml). FB2 (125-1,000 µM) is also cytotoxic to primary rat hepatocytes and induces hepatocyte nodule formation, a marker of...
| Keywords: | FB2,... |
| Application: | Apoptosis inducer |
| CAS | 116355-84-1 |
| MW: | 705.8 D |
From 192.00€
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15-keto Prostaglandin E2
Item number: Cay14720-1
15-keto Prostaglandin E2 (15-keto PGE2) is a metabolite of PGE2 (Cay-14010) formed by 15-hydroxy prostaglandin dehydrogenase (15-PGDH). Unlike PGE2, 15-keto PGE2 does not bind effectively to the PGE2 receptors EP2 and EP4 expressed in CHO cells (Kis = 2.6 and 15 µM, respectively) or induce adenylate cyclase activity...
| Keywords: | 15-keto PGE2, 15-keto-PGE2, 9,15-dioxo-11alpha-hydroxy-prosta-5Z,13E-dien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 26441-05-4 |
| MW: | 350.5 D |
From 97.00€
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Tauro-alpha-muricholic Acid (sodium salt)
Item number: Cay20288-1
Tauro-alpha-muricholic acid (TalphaMCA) is an antagonist of the farnesoid X receptor (FXR, IC50 = 28 µM) and a taurine-conjugated form of the murine-specific primary bile acid alpha-muricholic acid (Cay-20291). TalphaMCA is common in rodents but has also been found in small amounts in human serum.Formal Name:...
| Keywords: | Tauro-alpha-muricholate, TalphaMCA,... |
| Application: | Farnesoid X receptor (FXR) antagonist |
| CAS | 2260905-08-4 |
| MW: | 537.7 D |
260.00€
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