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(±)-Jasmonic Acid-d5
Item number: Cay29076-5
(±)-Jasmonic acid-d5 is intended for use as an internal standard for the quantification of jasmonic acid by GC- or LC-MS. Jasmonic acid (JA) is a plant growth regulator and derivative of alpha-linolenic acid (Cay-90210, Cay-21910) that can exist in four stereoisomeric forms. (-)-3(R),7(R)-JA and (+)-3(S),7(S)-JA...
| Keywords: | 3-oxo-2-(2Z)2-penten-1-yl-cyclopentane-2,4,4-d3-acetic-2,2-d2 acid |
| Application: | GC-MS, LC-MS, internal standard, plant growth regulator |
| CAS | 2750534-78-0 |
| MW: | 215.3 D |
From 360.00€
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Lipid-based Drug Delivery Tools
SM-102
Item number: Cay33474-50
SM-102 is an ionizable cationic amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of luciferase mRNA in SM-102-containing LNPs induces hepatic luciferase expression in mice. Formulations containing SM-102 have been used in the development...
| Keywords: | 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-octanoic acid, 1-octylnonyl ester |
| Application: | Ionizable amino lipid |
| CAS | 2089251-47-6 |
| MW: | 710.2 D |
From 147.00€
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Tirzepatide (sodium salt)
Item number: Cay39748-5
Tirzepatide is an agonist of glucagon-like peptide 1 receptor (GLP-1R) and gastric inhibitory polypeptide (GIP) receptor. It induces cAMP production in HEK293 cells expressing human GLP-1R or human GIP receptor (EC50s = 6.54 and 1.01 nM, respectively). Tirzepatide (100 nM) induces receptor internalization in HEK293...
| Keywords: | LY3298176,... |
| Application: | Dual GLP-1R / GIPR agonist |
| MW: | 4813.5 D |
From 42.00€
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4A3-SCC-10
Item number: Cay41276-10
4A3-SCC-10 is a disulfide bond-containing biodegradable ionizable cationic lipid (pKa = 6.22) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing 4A3-SCC-10 and encapsulating a Cy5-RNA reporter have improved endosomal escape ability over...
| Keywords: | ((methylazanediyl)bis(propane-3,1-diyl))bis(8,14-dioxo-7,15-dioxa-3,4,18,19-tetrathia-11-azahenicosane-11,1,21-triyl)... |
| Application: | Disulfide bond-containing biodegradable ionizable cationic lipid, LNP formation |
| MW: | 1948.1 D |
From 68.00€
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G0-C14
Item number: Cay37414-1
G0-C14 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vitro and in vivo. Administration of LNPs containing G0-C14 and encapsulating siRNA targeting CaMKIIgamma increases plaque stability and promotes macrophage efferocytosis of apoptotic...
| Keywords: | N-[2-[bis(2-hydroxytetradecyl)amino]ethyl]-16-hydroxy-14-(2-hydroxytetradecyl)-4,7-bis[3-[[2-[(2-hydroxytetradecyl)amino]e... |
| Application: | Ionizable cationic lipid, LNP generation |
| CAS | 1510653-27-6 |
| MW: | 1790.91 D |
From 97.00€
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Lipid Compound 48
Item number: Cay43418-1
Lipid compound 48 is an ionizable cationic lipid. InChI: InChI=1S/C45H89NO5/c1-5-8-11-14-19-26-33-42(4)50-44(48)36-29-22-17-24-31-38-46(40-41-47)39-32-25-18-23-30-37-45(49)51-43(34-27-20-15-12-9-6-2)35-28-21-16-13-10-7-3/h42-43,47H,5-41H2,1-4H3 InChIKey: BPRGRMGYJPIPFS-UHFFFAOYSA-N SMILES:...
| Keywords: | 8-[(2-hydroxyethyl)[8-[(1-methylnonyl)oxy]-8-oxooctyl]amino]-octanoic acid, 1-octylnonyl ester |
| Application: | Ionizable cationic lipid |
| CAS | 2089251-73-8 |
| MW: | 724.21 D |
From 73.00€
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1-Hexadecyl-3-methylimidazolium hexafluorophosphate
Item number: Cay44014-10
1-Hexadecyl-3-methylimidazolium hexafluorophosphate (C16mimPF6) is a long alkyl-chain imidazolium-based ionic liquid (LIL). It has been used in the formation of inclusion complexes with beta-cyclodextrin and as an electrolyte additive in aluminum-air batteries. Incorporation of C16mimPF6 (10-30 mol%) into...
| Keywords: | 1-Palmityl-3-methylimidazolium hexafluorophosphate, C16mimPF6, HDMIM.PF6, HMIH, 3-hexadecyl-1-methyl-1H-imidazolium,... |
| Application: | Ionic liquid |
| CAS | 219947-95-2 |
| MW: | 452.51 D |
From 44.00€
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Lipid ND-O1
Item number: Cay43010-1
Lipid ND-O1 is an ether-containing ionizable cationic lipid (pKa = 6.6) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vitro and in vivo. LNPs containing ND-O1 and encapsulating Cy5-labeled siRNA selectively accumulate in the liver over the spleen, heart, kidney, and...
| Keywords: | SM-86 Analog-2, heptadecan-9-yl 8-((8-(2-(hexyloxy)ethoxy)-8-oxooctyl)(2-hydroxyethyl)amino)octanoate |
| Application: | Ether-containing ionizable cationic lipid, LNP generation |
| MW: | 712.15 D |
From 88.00€
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Isostearic Acid
Item number: Cay43258-100
Isostearic acid is a branched-chain fatty acid. Formulations containing isosteric acid have been used in skin creams and cosmetics as emulsifiers and texturing agents. InChI: InChI=1S/C18H36O2/c1-17(2)15-13-11-9-7-5-3-4-6-8-10-12-14-16-18(19)20/h17H,3-16H2,1-2H3,(H,19,20) InChIKey: XDOFQFKRPWOURC-UHFFFAOYSA-N...
| Keywords: | Isooctadecanoic Acid, 16-methyl-heptadecanoic acid |
| Application: | Branched-chain fatty acid |
| CAS | 2724-58-5 |
| MW: | 284.48 D |
From 112.00€
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Lucidenic Acid D
Item number: Cay43525-1
Lucidenic acid D is a triterpenoid that has been found in G. lucidum and has antiviral and anti-inflammatory activities. It decreases levels of Epstein-Barr virus (EBV) early antigen in EBV-infected Raji cells in a concentration-dependent manner. Lucidenic acid D decreases ear edema induced by phorbol 12-myristate...
| Keywords: | Lucidenic Acid D2, (5alpha,12beta)-12-(acetyloxy)-4,4,14-trimethyl-3,7,11,15- tetraoxo-chol-8-en-24-oic acid |
| Application: | Triterpenoid, antiviral, antiinflammatory agent |
| CAS | 98665-16-8 |
| MW: | 514.62 D |
From 142.00€
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VT-1161
Item number: Cay43577-1
VT-1161 is an antifungal agent. It selectively binds to C. albicans lanosterol 14-alpha-demethylase (Kd = 39 nM), also known as cytochrome P450 (CYP) isoform CYP51, over human lanosterol 14-alpha-demethylase at 86 µM and does not inhibit human CYP2C9, CYP2C19, or CYP3A4 (IC50s = 99, 72, and 65 µM, respectively)....
| Keywords: | Oteseconazole,... |
| Application: | Antifungal agent, ergosterol biosynthesis inhibitor |
| CAS | 1340593-59-0 |
| MW: | 527.4 D |
From 97.00€
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Rilapladib
Item number: Cay43593-10
Rilapladib is an inhibitor of platelet-activating factor acetylhydrolase (PAF-AH), also known as lipoprotein-associated phospholipase A2 (Lp-PLA2, IC50 = 230 pM). InChI:...
| Keywords: | SB 659032, 2-[[(2,3-difluorophenyl)methyl]thio]-N-... |
| Application: | PAF-AH inhibitor |
| CAS | 412950-08-4 |
| MW: | 735.81 D |
From 409.00€
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