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HET0016
Item number: Cay75780-10
20-HETE is a major biologically active cytochrome P450 (CYP450) metabolite of arachidonic acid in the kidney and liver. It regulates renal vascular and tubular functions as well as vascular tone in the cerebral circulation. HET0016 is an inhibitor of 20-HETE formation in human renal microsomes with an IC50 of 8.9...
| Keywords: | N-hydroxy-N'-(4-n-butyl-2-methylphenyl)Formamidine, N-(4-butyl-2-methylphenyl)-N'-hydroxy-methanimidamide |
| Application: | Bioactive lipid assays |
| CAS | 339068-25-6 |
| MW: | 206.3 D |
From 26.00€
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ALC-0315
Item number: Cay34337-100
ALC-0315 is an ionizable cationic amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of severe acute respiratory coronavirus 2 (SARS-CoV-2) mRNA in ALC-0315-containing LNPs induces the production of IgG that binds to the SARS-CoV-2...
| Keywords: | 2-hexyl-decanoic acid, 1,1'-[[(4-hydroxybutyl)imino]di-6,1-hexanediyl] ester |
| Application: | Ionizable amino lipid, lipid nanoparticle formation |
| CAS | 2036272-55-4 |
| MW: | 766.3 D |
From 281.00€
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(±)14(15)-DiHET
Item number: Cay51651-25
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. (±)14(15)-DiHET is the urinary metabolite of (±)14(15)-EET (Cay-50651) which has been documented by GC-MS to be elevated in pregnancy-induced hypertension.Formal Name:...
| Keywords: | (±)14,15-DiHETrE, (±)14,15-dihydroxy-5Z,8Z,11Z-eicosatrienoic acid |
| Application: | Bioactive lipid studies |
| MW: | 338.5 D |
From 157.00€
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(±)14(15)-EET-d11
Item number: Cay10006410-25
(±)14(15)-EET-d11 is intended for use as an internal standard for the quantification of (±)14(15)-EET (Cay-50651) by GC- or LC-MS. 14(S),15(R)-EET and 14(R),15(S)-EET are formed via epoxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) by a variety of cytochrome P450 (CYP) isoforms. 14(S),15(R)-EET...
| Keywords: | (±)14,15-EET-d11, (±)14,15-EpETrE-d11, (±)14(15)-epoxy-5Z,8Z,11Z-eicosatrienoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid |
| Application: | Standard |
| MW: | 331.5 D |
From 273.00€
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N-butyryl-L-Homoserine lactone
Item number: Cay10007898-10
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators...
| Keywords: | C4-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-butanamide |
| Application: | Bioactive lipid assays |
| CAS | 67605-85-0 |
| MW: | 171.2 D |
From 49.00€
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Prostaglandin H2
Item number: Cay17020-100
Prostaglandin H2 (PGH2) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor. PGH2 is the precursor for all 2-series PGs and thromboxanes (TXs), and is a TP receptor agonist which irreversibly aggregates human platelets at 50-100...
| Keywords: | PGH2, 9alpha,11alpha-epidioxy-15S-hydroxy-prosta-5Z,13E-dien-1-oic acid |
| Application: | TP receptor agonist |
| CAS | 42935-17-1 |
| MW: | 352.5 D |
From 127.00€
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Tauro-omega-muricholic Acid (sodium salt)
Item number: Cay28842-1
Tauro-omega-muricholic acid is a taurine-conjugated form of the secondary bile acid omega-muricholic acid (Cay-20292). Hepatic levels of tauro-omega-muricholic acid are decreased in mice following a diet supplemented with cholic, deoxycholic, chenodeoxycholic, or ursodeoxycholic acid and in a high-fat diet-induced...
| Keywords: | TOMCA, T-omega-MCA,... |
| Application: | Taurine-conjugated, secondary bile acid |
| CAS | 2456348-84-6 |
| MW: | 537.7 D |
From 286.00€
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12(S)-HHTrE
Item number: Cay34590-25
12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of human platelets. It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. 12(S)-HHTrE is a natural lipid agonist of the leukotriene B2 receptor BLT2 in...
| Keywords: | 12(S)-HHT, 12S-hydroxy-5Z,8E,10E-heptadecatrienoic acid |
| Application: | Bioactive lipid studies |
| CAS | 54397-84-1 |
| MW: | 280.4 D |
From 181.00€
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Arachidonoyl Glycine
Item number: Cay90051-5
Arachidonoyl glycine (N-arachidonyl glycine, NAGly) has been isolated from cell cultures treated with arachidonoyl ethanolamide (AEA, anandamide), from extracts of mammalian brain, and has also been synthesized as an analog of AEA for structure/activity testing. NAGly may be produced endogenously via oxidation of...
| Keywords: | N-Arachidonyl Glycine, NAGly, N-[1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl]-glycine |
| Application: | Analgesic activities |
| CAS | 179113-91-8 |
| MW: | 361.5 D |
From 62.00€
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Pentadecanoic Acid
Item number: Cay17399-50
Pentadecanoic acid is a 15:0 saturated fatty acid found in esterified form in the lipids of many bacterial species and in the milk fat of ruminants. It has been used as a biological marker for the intake of dairy fat in the assessment of metabolic risk factors.Formal Name: Pentadecanoic acid. CAS Number: 1002-84-2....
| Keywords: | C15:0, NSC 28486, Pentadecylic Acid, Pentadecanoic acid |
| Application: | Dairy fat intake biological marker |
| CAS | 1002-84-2 |
| MW: | 242.4 D |
From 54.00€
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3-hydroxy Lauric Acid methyl ester
Item number: Cay24643-10
3-hydroxy Lauric acid methyl ester is a hydroxylated fatty acid methyl ester that has been found in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by P. putida and D. tsuruhatensis. [Matreya, LLC. Catalog No. 1732]Formal Name: 3-hydroxy-dodecanoic acid, methyl ester. CAS Number: 72864-23-4....
| Keywords: | Methyl 3-Hydroxydodecanoate, Methyl beta-Hydroxydodecanoate, 3-hydroxy-dodecanoic acid, methyl ester |
| Application: | Hydroxylated fatty acid methyl ester |
| CAS | 72864-23-4 |
| MW: | 230.3 D |
From 60.00€
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13,14-dihydro-15-keto Prostaglandin E2
Item number: Cay14650-1
13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 (Cay-14010) and the primary PGE2 metabolite in plasma. It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG Delta13 reductase. Unlike PGE2, 13,14-dihydro-15-keto PGE2 does not bind effectively to the PGE2...
| Keywords: | 13,14-dihydro-15-keto PGE2, 9,15-dioxo-11alpha-hydroxy-prost-5Z-en-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 363-23-5 |
| MW: | 352.5 D |
From 103.00€
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