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Lipid PPz-2R1
Item number: Cay43160-1
Lipid PPz-2R1 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing lipid PPz-2R1 and encapsulating an mRNA reporter selectively accumulate in lungs over the heart, liver, spleen, and kidneys in mice. LNPs...
| Keywords: | piperazine-1,4-diylbis(hexane-6,1-diyl) bis(2-hexyldecanoate) |
| Application: | Ionizable cationic lipidoid, LNP formation |
| CAS | 2832061-40-0 |
| MW: | 763.29 D |
103.00€
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Lipid H7T4-4
Item number: Cay43860-1
Lipid H7T4-4 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing lipid H7T4-4 and encapsulating an mRNA reporter induce luciferase expression in AsPC-1 pancreatic cancer cells in vitro and in an AsPC-1 mouse...
| Keywords: | 1,1',1'',1'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetrakis(tetradecan-2-ol) |
| Application: | Ionizable cationic lipid, LNP generation |
| MW: | 1021.78 D |
From 138.00€
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BSA-NBD-Stearate Saturated Fatty Acid Complex (1 mM)
Item number: Cay44253-5
BSA-NBD-Stearate saturated fatty acid complex is composed of NBD-stearic acid (Cay-10011299) and fatty acid-free bovine serum albumin (BSA) at an approximately 6:1 molar ratio of NBD-stearate:BSA. It can be used for efficient fatty acid delivery to cells in culture for the purpose of monitoring fatty acid oxidation...
| Keywords: | Bovine Serum Albumin-NBD-Octadecanoic Acid, Bovine Serum Albumin-NBD-Stearate Saturated Fatty Acid, BSA-NBD-Octadecanoic Acid |
| Application: | Fatty acid substrate, cell culture |
309.00€
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BP Lipid 229
Item number: Cay44269-10
BP lipid 229 is an ionizable cationic lipid (pKa = 5.8) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro. LNPs containing BP lipid 229 and encapsulating an mRNA reporter induce luciferase expression in HeLa cells. InChI:...
| Keywords: | 8,8'-[(2-hydroxyethyl)imino]bis-octanoic acid, 1,1'-bis(1-octylnonyl) |
| Application: | Ionizable cationic lipid, LNP generation |
| CAS | 2089251-55-6 |
| MW: | 822.4 D |
From 53.00€
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BP Lipid 700
Item number: Cay44388-10
BP lipid 700 is an ionizable cationic lipid. InChI: InChI=1S/C42H83NO7/c1-5-9-13-17-19-23-27-39(25-21-15-11-7-3)41(45)49-37-35-47-33-30-43(29-32-44)31-34-48-36-38-50-42(46)40(26-22-16-12-8-4)28-24-20-18-14-10-6-2/h39-40,44H,5-38H2,1-4H3, InChIKey: XWFJVICUTRYVHP-UHFFFAOYSA-N, SMILES:...
| Keywords: | ((((2-hydroxyethyl)azanediyl)bis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-hexyldecanoate) |
| Application: | Ionizable cationic lipid |
| CAS | 2985008-78-2 |
| MW: | 714.13 D |
From 53.00€
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(±)18-HEPE
Item number: Cay32840-25
(±)18-HEPE is produced by non-enzymatic oxidation of eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). 18-HEPE levels are increased in the plasma and heart, as well as in the supernatant of cultured peritoneal macrophages isolated from fat-1 transgenic mice that are capable of endogenously producing...
| Keywords: | (±)-18-hydroxy-5Z,8Z,11Z,14Z,16E-eicosapentaenoic acid |
| Application: | Bioactive lipid studies |
| CAS | 141110-17-0 |
| MW: | 318.5 D |
From 192.00€
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25-Hydroxyvitamin D3
Item number: LKT-H9815.1
25-hydroxyvitamin D3 (25-OH D3), or calcidiol/calcifediol, is a pro-hormone for calcitriol that restores bone mineralization in vitamin D-deficient models. 25-OH D3 is the major circulating metabolite of vitamin D3. Vitamin D signaling also regulates Ca2+ homeostasis. 25-OH D3 activates the vitamin D receptor and...
| Keywords: | Calcifediol, calcidiol, 25-hydroxycholecalciferol |
| Application: | Vitamin D3 metabolite |
| CAS | 19356-17-3 |
| MW: | 400,64 D |
From 184.00€
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Ganglioside GD1b . disodium salt (bovine brain)
Item number: AG-CN2-9004-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Keywords: | GD1b . 2Na, Disialoganglioside GD1b . 2Na |
| Application: | Acidic glycosphingolipid |
| CAS | 19553-76-5 |
| MW: | 1836,1 D |
193.00€
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(±)8(9)-DiHET
Item number: Cay51351-25
(±)8(9)-DiHET is an oxylipin and a racemic mixture of the arachidonic acid metabolites 8(S),9(R)-DiHET and 8(R),9(S)-DiHET. It is formed from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) via an (±)8(9)-EET (Cay-50351) intermediate by epoxide hydrolases. (±)8(9)-DiHET (1 µM) induces cAMP production in...
| Keywords: | (±)8,9-DiHETrE, (±)8,9-dihydroxy-5Z,11Z,14Z-eicosatrienoic acid |
| Application: | Bioactive lipid assays |
| CAS | 192461-96-4 |
| MW: | 338.5 D |
From 151.00€
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Palmitoyl Ethanolamide-d4
Item number: Cay10007824-100
Palmitoyl ethanolamide-d4 (PEA-d4) is intended for use as an internal standard for the quantification of PEA (Cay-90350) by GC- or LC-MS. PEA is an endogenous fatty N-acyl ethanolamine and a derivative of the endocannabinoid arachidonoyl ethanolamide (AEA, Cay-90050). It selectively activates peroxisome...
| Keywords: | Palmidrol-d4, PEA-7,7,8,8-d4, N-(2-hydroxyethyl)-hexadecanamide-7,7,8,8-d4 |
| Application: | Standard |
| CAS | 1159908-45-8 |
| MW: | 303.5 D |
From 38.00€
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URB597
Item number: Cay10046-10
URB597 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH), the enzyme that hydrolyzes anandamide (AEA, Cay-90050) and other simple esters and amides with long unsaturated acyl chains (IC50 = 4.6 nM and 0.5 nM in brain membranes and intact neurons, respectively). URB597 exhibits both...
| Keywords: | (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamate |
| Application: | FAAH inhibitor |
| CAS | 546141-08-6 |
| MW: | 338.4 D |
From 52.00€
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5(S),15(S)-DiHETE
Item number: Cay35280-25
5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE. It potentiates the degranulation of human PMNL in response to PAF, but not fMLP, calcium ionophore A23187, or LTB4. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED50 value of 0.3 µM.Formal Name: 5S,15S-dihydroxy-6E,8Z,10Z,13E-eicosatetraenoic...
| Keywords: | 5S,15S-dihydroxy-6E,8Z,10Z,13E-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 82200-87-1 |
| MW: | 336.5 D |
From 145.00€
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