No results were found for the filter!
URB597
Item number: Cay10046-10
URB597 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH), the enzyme that hydrolyzes anandamide (AEA, Cay-90050) and other simple esters and amides with long unsaturated acyl chains (IC50 = 4.6 nM and 0.5 nM in brain membranes and intact neurons, respectively). URB597 exhibits both...
| Keywords: | (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamate |
| Application: | FAAH inhibitor |
| CAS | 546141-08-6 |
| MW: | 338.4 D |
From 44.00€
*
(±)14(15)-DiHET
Item number: Cay51651-25
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. (±)14(15)-DiHET is the urinary metabolite of (±)14(15)-EET (Cay-50651) which has been documented by GC-MS to be elevated in pregnancy-induced hypertension.Formal Name:...
| Keywords: | (±)14,15-DiHETrE, (±)14,15-dihydroxy-5Z,8Z,11Z-eicosatrienoic acid |
| Application: | Bioactive lipid studies |
| MW: | 338.5 D |
From 132.00€
*
N-butyryl-L-Homoserine lactone
Item number: Cay10007898-10
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators...
| Keywords: | C4-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-butanamide |
| Application: | Bioactive lipid assays |
| CAS | 67605-85-0 |
| MW: | 171.2 D |
From 44.00€
*
Prostaglandin H2
Item number: Cay17020-100
Prostaglandin H2 (PGH2) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor. PGH2 is the precursor for all 2-series PGs and thromboxanes (TXs), and is a TP receptor agonist which irreversibly aggregates human platelets at 50-100...
| Keywords: | PGH2, 9alpha,11alpha-epidioxy-15S-hydroxy-prosta-5Z,13E-dien-1-oic acid |
| Application: | TP receptor agonist |
| CAS | 42935-17-1 |
| MW: | 352.5 D |
From 103.00€
*
DMG-PEG(2000)
Item number: Cay33945-500
DMG-PEG(2000) is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of fumarylacetoacetate hydrolase (FAH) mRNA in DMG-PEG(2000)-containing LNPs increases survival in a mouse model of hereditary tyrosinemia type 1 (HT-1). Formulations...
| Keywords: | 1,2-Dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000,... |
| Application: | Lipid excipient |
| CAS | 160743-62-4 |
From 184.00€
*
C12-200
Item number: Cay36699-50
C12-200 is a branched-chain ionizable cationic lipidoid. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA, siRNA, or self-amplifying RNA (saRNA). Administration of human erythropoietin (EPO) mRNA or factor VII siRNA in C12-200-containing LNPs...
| Keywords: | 1,1'-[[2-[4-[2-[[2-[bis(2-hydroxydodecyl)amino]ethyl](2-hydroxydodecyl)amino]ethyl]-1-piperazinyl]ethyl]imino]bis-2-dodecanol |
| Application: | Branched-chain ionizable lipidoid |
| CAS | 1220890-25-4 |
| MW: | 1136.9 D |
From 144.00€
*
12(S)-HHTrE
Item number: Cay34590-25
12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of human platelets. It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. 12(S)-HHTrE is a natural lipid agonist of the leukotriene B2 receptor BLT2 in...
| Keywords: | 12(S)-HHT, 12S-hydroxy-5Z,8E,10E-heptadecatrienoic acid |
| Application: | Bioactive lipid studies |
| CAS | 54397-84-1 |
| MW: | 280.4 D |
From 166.00€
*
Arachidonoyl Glycine
Item number: Cay90051-5
Arachidonoyl glycine (N-arachidonyl glycine, NAGly) has been isolated from cell cultures treated with arachidonoyl ethanolamide (AEA, anandamide), from extracts of mammalian brain, and has also been synthesized as an analog of AEA for structure/activity testing. NAGly may be produced endogenously via oxidation of...
| Keywords: | N-Arachidonyl Glycine, NAGly, N-[1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl]-glycine |
| Application: | Analgesic activities |
| CAS | 179113-91-8 |
| MW: | 361.5 D |
From 57.00€
*
H1L1A1B3
Item number: Cay41199-5
H1L1A1B3 is an ionizable cationic lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of circular RNA (circRNA) in vitro and in vivo. LNPs containing H1L1A1B3 and encapsulating circRNA encoding IL-12 induce IL-12 production four times more...
| Keywords: | 7-(cyclohexylamino)-6-(N-(3-(dimethylamino)propyl)-4-methylnonanamido)-7-oxoheptyl dodecanoate |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 664.1 D |
From 136.00€
*
DSPE-PEG(2000) Maleimide
Item number: Cay42013-10
DSPE-PEG(2000) maleimide is a PEGylated derivative of 1,2-distearoyl-rac-3-PE (DSPE). It has been used in the synthesis of lipid nanoparticles (LNPs) for the delivery of siRNA or small molecule anticancer agents in vitro and in vivo. LNPs containing DSPE-PEG(2000) maleimide and encapsulating siRNAs targeting mRNA...
| Keywords: | 1,2-Distearoyl-rac-glycero-3-Phosphoethanolamine-PEG-2000 Maleimide,... |
| Application: | PEGylated DSPE derivative, LNP formation |
| CAS | 185844-12-6 |
From 134.00€
*
15(R)-15-methyl Prostaglandin D2
Item number: Cay12720-1
15(R)-15-methyl Prostaglandin D2 (15(R)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2 (Cay-12010). The physiological actions of PGD2 include regulation of sleep, lowering of body temperature, inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 mediates its effects...
| Keywords: | 15(R)-15-methyl PGD2, 9alpha,15R-dihydroxy-11-oxo-15-methyl-prosta-5Z,13E-dien-1-oic acid |
| Application: | CRTH2 receptor agonist, DP2 receptor agonist |
| CAS | 210978-26-0 |
| MW: | 366.5 D |
From 48.00€
*
Pentadecanoic Acid
Item number: Cay17399-50
Pentadecanoic acid is a 15:0 saturated fatty acid found in esterified form in the lipids of many bacterial species and in the milk fat of ruminants. It has been used as a biological marker for the intake of dairy fat in the assessment of metabolic risk factors.Formal Name: Pentadecanoic acid. CAS Number: 1002-84-2....
| Keywords: | C15:0, NSC 28486, Pentadecylic Acid, Pentadecanoic acid |
| Application: | Dairy fat intake biological marker |
| CAS | 1002-84-2 |
| MW: | 242.4 D |
From 49.00€
*