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(±)5(6)-DiHET
Item number: Cay51211-25
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET (Cay-50211, Cay-10007260) by epoxide hydrolases. 5(6)-DiHET can be used to quantify 5(6)-EET due to the conversion of 5(6)-EET to 5(6)-delta-lactone in solution. 5(6)-DiHET activates large-conductance calcium-activated...
| Keywords: | (±)5,6-DiHETrE, (±)5,6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid |
| Application: | Bioactive lipid assays |
| CAS | 213382-49-1 |
| MW: | 338.5 D |
From 138.00€
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TOFA
Item number: Cay10005263-5
Inhibition of fatty acid synthase (FASN) by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines. TOFA is an inhibitor of fatty acid synthesis blocking the synthesis of malonyl-CoA by acetyl-CoA carboxylase (ACC). Both cerulenin (at about 10 µg/ml) and TOFA (at about 1...
| Keywords: | 5-(Tetradecyloxy)-2-furoic Acid, RMI 14514, 5-(tetradecyloxy)-2-furancarboxylic acid |
| Application: | Bioactive lipid assays |
| CAS | 54857-86-2 |
| MW: | 324.5 D |
From 56.00€
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Prostaglandin A2
Item number: Cay10210-1
Prostaglandin A2 (PGA2) is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. PGA2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity. At a 25 µM concentration, PGA2 blocks the cell cycle...
| Keywords: | Medullin, PGA2, 9-oxo-15S-hydroxy-prosta-5Z,10,13E-trien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 13345-50-1 |
| MW: | 334.5 D |
From 79.00€
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Heneicosapentaenoic Acid methyl ester
Item number: Cay11622-5
Heneicosapentaenoic Acid (HPA) is a fatty acid present in trace amounts in the green algae Bryopsis pennata Lamouroux and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA) except elongated with one carbon on the carboxyl end, placing the first double bond in the Delta6 position. HPA...
| Keywords: | HPA methyl ester, 6Z,9Z,12Z,15Z,18Z-heneicosapentaenoic acid, methyl ester |
| Application: | Lipid studies |
| CAS | 65919-53-1 |
| MW: | 330.5 D |
From 161.00€
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Sphingosine (d18:1)
Item number: Cay10007907-10
Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase. Phosphorylation of sphingosine by sphingosine kinases 1 and 2 (SPHK 1, SPHK 2) produces...
| Keywords: | (-)-Sphingosine, D-erythro-Sphingosine C-18, 2S-amino-4E-octadecene-1,3R-diol |
| Application: | Bioactive lipid assays |
| CAS | 123-78-4 |
| MW: | 299.5 D |
From 73.00€
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Resolvin D2-d5
Item number: Cay11184-10
Resolvin D2-d5 (RvD2-d5) is intended for use as an internal standard for the quantification of resolvin D2 (Cay-10007279) by GC- or LC-MS. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). In addition to being anti-inflammatory, resolvins...
| Keywords: | 7(S),16(R),17(S)-Resolvin D2-d5, RvD2-d5, 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-21,21',22,22,22-d5 docosahexaenoic acid |
| Application: | Standard, bioactive lipid assays |
| CAS | 1881277-33-3 |
| MW: | 381.5 D |
From 302.00€
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(±)12-HETE
Item number: Cay34550-25
(±)12-HETE is a racemic mixture of the arachidonic acid metabolites 12(R)-HETE (Cay-34560) and 12(S)-HETE (Cay-34570). It is formed via non-enzymatic oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). 12(S)- and 12(R)-HETE are formed by 12S- and 12R-lipoxygenase-mediated oxidation of arachidonic...
| Keywords: | (±)12-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid studies |
| CAS | 71030-37-0 |
| MW: | 320.5 D |
From 118.00€
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(±)9(10)-DiHOME
Item number: Cay53400-100
(±)9(10)-DiHOME is the diol form of (±)9(10)-EpOME (Cay-52400), a cytochrome P450-derived epoxide of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) also known as leukotoxin. It is formed from 9(10)-EpOME by soluble epoxide hydrolase (sEH) in neutrophils. It is toxic to Sf21 cells expressing sEH and to...
| Keywords: | Leukotoxin diol, (±)9,10-dihydroxy-12Z-octadecenoic acid |
| Application: | Cytotoxic agent |
| CAS | 263399-34-4 |
| MW: | 314.5 D |
From 53.00€
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Leukotriene C4-d5
Item number: Cay10006198-25
Leukotriene C4-d5 (LTC4-d5) contains five deuterium atoms at the 19, 19', 20, 20 and 20 positions. It is intended for use as an internal standard for the quantification of LTC4 by GC- or LC-mass spectrometry. LTC4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione...
| Keywords: | LTC4-d5, 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-d5-eicosatetraenoic acid |
| Application: | Standard |
| CAS | 1441421-73-3 |
| MW: | 630.8 D |
From 433.00€
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Lipoxin A4-d5
Item number: Cay10007737-10
Lipoxin A4-d5 (LXA4-d5) contains five deuterium atoms at the 19, 19', 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of LXA4 by GC- or LC-mass spectrometry (MS). LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or...
| Keywords: | 5(S),6(R),15(S)-TriHETE-d5, 5(S),6(R)-LXA4-d5, 5S,6R,15S-trihydroxyicosa-7E,9E,11Z,13E-tetraenoic-19,19,20,20,20-d5 acid |
| Application: | Standard |
| CAS | 1622429-53-1 |
| MW: | 357.5 D |
From 295.00€
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Quercetin (hydrate)
Item number: Cay10005169-5
Quercetin is an abundant flavonoid that has been isolated from a variety of fruits and vegetables and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and...
| Keywords: | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, hydrate |
| Application: | Bioactìve flavonoid |
| CAS | 849061-97-8 |
| MW: | 302.2 D |
53.00€
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C2 Adamantanyl Glucosylceramide (d18:1/2:0)
Item number: Cay24623-1
C2 Adamantanyl glucosylceramide (AdaGluCer) is a bioactive sphingolipid. It increases levels of glycosphingolipids in Vero cells at low concentrations (=20 µM) but decreases them at high concentrations (>40 µM). Pretreatment of microsomes with AdaGluCer increases production of adamantanyl lactosylceramide...
| Keywords: | AdaGluCer(d18:1/2:0), Adamantanyl GluCer(d18:1/2:0), Adamantanyl Glucosylceramide (d18:1/2:0), N-(1-Adamantaneacetyl)... |
| Application: | Bioactive sphingolipid |
| MW: | 635.87 D |
344.00€
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