Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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1-Oleoyl-2-hydroxy-sn-glycero-3-PA
1-Oleoyl-2-hydroxy-sn-glycero-3-PA

Item number: Cay10010093-5

1-Oleoyl-2-hydroxy-sn-glycero-3-PA (1-Oleoyl LPA) is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by...
Keywords: 1-Oleoyl LPA, Oleoyl-sn-3-Glycerophosphate, 1-O-9Z-octadecenoyl-sn-glyceryl-3-phosphoric acid
Application: Bioactive lipid assays
CAS 65528-98-5
MW: 436.5 D
From 36.00€ *
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C16 Ceramide (d18:1/16:0)
C16 Ceramide (d18:1/16:0)

Item number: Cay10681-1

C16 Ceramide is a sphingolipid. It incorporates into the mitochondrial outer membrane and forms channels that increase its permeability. C16 Ceramide levels are increased by PPMP or MAPP in isolated human neutrophils and are correlated with an increase in apoptosis. It accumulates in the lungs of patients with...
Keywords: Cer(d18:1/16:0), Ceramide (d18:1/16:0), N-Palmitoyl-D-erythro-Sphingosine, Palmitoyl Ceramide,...
Application: Bioactive lipid assays
CAS 24696-26-2
MW: 537.9 D
From 31.00€ *
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beta-Muricholic Acid
beta-Muricholic Acid

Item number: Cay20287-1

beta-Muricholic acid (beta-MCA) is a murine-specific primary bile acid. Dietary administration of beta-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet. Dietary administration of beta-MCA also dissolves 100% of gallstones in a gallstone-susceptible...
Keywords: 5beta-Cholanic Acid-3alpha,6beta,7beta-triol, beta-MCA, (5beta)-3alpha,6beta,7beta-trihydroxy-cholan-24-oic acid
CAS 2393-59-1
MW: 408.6 D
From 161.00€ *
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(±)5(6)-DiHET
(±)5(6)-DiHET

Item number: Cay51211-25

5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET (Cay-50211, Cay-10007260) by epoxide hydrolases. 5(6)-DiHET can be used to quantify 5(6)-EET due to the conversion of 5(6)-EET to 5(6)-delta-lactone in solution. 5(6)-DiHET activates large-conductance calcium-activated...
Keywords: (±)5,6-DiHETrE, (±)5,6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid
Application: Bioactive lipid assays
CAS 213382-49-1
MW: 338.5 D
From 126.00€ *
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Resolvin D2-d5
Resolvin D2-d5

Item number: Cay11184-10

Resolvin D2-d5 (RvD2-d5) is intended for use as an internal standard for the quantification of resolvin D2 (Cay-10007279) by GC- or LC-MS. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). In addition to being anti-inflammatory, resolvins...
Keywords: 7(S),16(R),17(S)-Resolvin D2-d5, RvD2-d5, 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-21,21',22,22,22-d5 docosahexaenoic acid
Application: Standard, bioactive lipid assays
CAS 1881277-33-3
MW: 381.5 D
From 231.00€ *
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(±)12-HETE
(±)12-HETE

Item number: Cay34550-25

(±)12-HETE is a racemic mixture of the arachidonic acid metabolites 12(R)-HETE (Cay-34560) and 12(S)-HETE (Cay-34570). It is formed via non-enzymatic oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). 12(S)- and 12(R)-HETE are formed by 12S- and 12R-lipoxygenase-mediated oxidation of arachidonic...
Keywords: (±)12-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid
Application: Bioactive lipid studies
CAS 71030-37-0
MW: 320.5 D
From 99.00€ *
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Leukotriene C4-d5
Leukotriene C4-d5

Item number: Cay10006198-25

Leukotriene C4-d5 (LTC4-d5) contains five deuterium atoms at the 19, 19', 20, 20 and 20 positions. It is intended for use as an internal standard for the quantification of LTC4 by GC- or LC-mass spectrometry. LTC4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione...
Keywords: LTC4-d5, 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-d5-eicosatetraenoic acid
Application: Standard
CAS 1441421-73-3
MW: 630.8 D
From 398.00€ *
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(±)19(20)-DiHDPA
(±)19(20)-DiHDPA

Item number: Cay10007001-50

Docosahexaenoic acid (DHA, Cay-90310) is an essential fatty acid and the most abundant omega-3 fatty acid in neural tissues, especially in the retina and brain. (±)19(20)-DiHDPA is one of the major metabolites produced when DHA is incubated with NADPH-supplemented rat liver microsomes. DHA is also slowly metabolized...
Keywords: (±)19,20-DiHDoPE, (±)19,20-dihydroxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid
Application: Bioactive lipid assays
MW: 362.5 D
From 116.00€ *
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9(S)-HODE
9(S)-HODE

Item number: Cay38410-100

9(S)-HODE is a metabolite of the omega-6 polyunsaturated fatty acid linoleic acid (Cay-90150, Cay-90150.1, Cay-21909). It is formed from linoleic acid by lipoxygenases. 9(S)-HODE (68 µM) increases transactivation of peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma in reporter assays using...
Keywords: 9S-hydroxy-10E,12Z-octadecadienoic acid
Application: Bioactive lipid studies
CAS 73543-67-6
MW: 296.5 D
From 161.00€ *
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Filipin III
Filipin III

Item number: Cay70440-1

Filipin III is a polyene and an active component of the polyene antibiotic filipin complex (Cay-25073). It is active against various fungi, including B. dermatitidis, C. neoformans, H. capsulatum, C. albicans, and T. mentagrophytes (MICs = 1-10 µg/ml). Filipin III induces hemolysis of isolated rabbit erythrocytes...
Keywords: 4S,6S,8S,10R,12R,14R,16S,27S-octahydroxy-3R-(1R-hydroxy-hexyl)17,28R-dimethyl-oxacyclooctacosa-17E,19E,21E,21E,23E,25E-pen...
Application: Bioactive lipid assays
CAS 480-49-9
MW: 654.8 D
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(±)18-HEPE
(±)18-HEPE

Item number: Cay32840-25

(±)18-HEPE is produced by non-enzymatic oxidation of eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). 18-HEPE levels are increased in the plasma and heart, as well as in the supernatant of cultured peritoneal macrophages isolated from fat-1 transgenic mice that are capable of endogenously producing...
Keywords: (±)-18-hydroxy-5Z,8Z,11Z,14Z,16E-eicosapentaenoic acid
Application: Bioactive lipid studies
CAS 141110-17-0
MW: 318.5 D
From 161.00€ *
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Resolvin D5
Resolvin D5

Item number: Cay10007280-10

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D5 (RvD5) is a DHA-derived...
Keywords: 7(S),17(S)-diHDHA, 7(S),17(S)-Resolvin D5, RvD5, 7S,17S-dihydroxy-4Z,8E,10Z,13Z,15E,19Z-docosahexaenoic acid
Application: Lipid mediator
CAS 578008-43-2
MW: 360.5 D
From 209.00€ *
Review
16 from 331 pages