Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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17-Octadecynoic Acid
17-Octadecynoic Acid

Item number: Cay90270-1

17-Octadecynoic Acid (17-ODYA) is a fatty acid alkyne. It is a suicide inhibitor of leukotriene B4 20-hydroxylase and renal CYP450 omega-hydroxylase. 17-ODYA (10 µM) completely inhibits the bradykinin-dependent transport of sodium chloride in rat TALH cells. It has been used as a click chemistry probe for labeling...
Keywords: 17-ODYA, Alk-16
Application: Bioactive lipid assays
CAS 34450-18-5
MW: 280.5 D
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Docosahexaenoyl Ethanolamide
Docosahexaenoyl Ethanolamide

Item number: Cay10007534-5

Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant omega-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for...
Keywords: DEA, DHEA, Synaptamide, N-(2-hydroxyethyl)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenamide
Application: Bioactive lipid assays
CAS 162758-94-3
MW: 371.6 D
From 53.00€ *
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6-keto Prostaglandin F1alpha-d4
6-keto Prostaglandin F1alpha-d4

Item number: Cay315210-25

6-keto Prostaglandin F1alpha-d4 (6-keto PGF1alpha-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 6-keto PGF1alpha (Cay-15210) by GC- or LC-MS. 6-keto PGF1alpha is the inactive, non-enzymatic hydrolysis product of PGI2....
Keywords: 6-keto PGF1alpha-d4, 6-oxo-9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic-3,3,4,4-d4 acid
Application: Standard
CAS 82414-64-0
MW: 374.5 D
From 102.00€ *
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C16 Ceramide (d18:1/16:0)
C16 Ceramide (d18:1/16:0)

Item number: Cay10681-1

C16 Ceramide is a sphingolipid. It incorporates into the mitochondrial outer membrane and forms channels that increase its permeability. C16 Ceramide levels are increased by PPMP or MAPP in isolated human neutrophils and are correlated with an increase in apoptosis. It accumulates in the lungs of patients with...
Keywords: Cer(d18:1/16:0), Ceramide (d18:1/16:0), N-Palmitoyl-D-erythro-Sphingosine, Palmitoyl Ceramide,...
Application: Bioactive lipid assays
CAS 24696-26-2
MW: 537.9 D
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8-iso Prostaglandin F2alpha-d4
8-iso Prostaglandin F2alpha-d4

Item number: Cay316350-25

8-iso PGF2alpha-d4 is intended for use as an internal standard for the quantification of 8-iso PGF2alpha by GC- or LC-mass spectrometry. 8-iso Prostaglandin F2alpha (8-iso PGF2alpha) is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It circulates in human...
Keywords: 15-F2t-Isoprostane-d4, 8-epi PGF2alpha-d4, 8-Isoprostane-d4, iPF2alpha-III-d4,...
Application: Standard
CAS 211105-40-7
MW: 358.5 D
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5(S)-HpETE
5(S)-HpETE

Item number: Cay44230-25

5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. It is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs. 5(S)-HpETE (1 µM) mediates the induction of the proto-oncogene c-fos in TNF-stimulated TA1 cells.Formal Name:...
Keywords: 5S-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 71774-08-8
MW: 336.5 D
From 159.00€ *
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(±)11(12)-DiHET
(±)11(12)-DiHET

Item number: Cay51511-25

Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. (±)11(12)-DiHET relaxes U-46619 (Cay-16450)-contracted artery rings with approximately 70% of the magnitude of (±)11(12)-EET (Cay-50511).Formal Name: (±)11,12-dihydroxy-5Z,8Z,14Z-eicosatrienoic...
Keywords: (±)11,12-DiHETrE, (±)11,12-dihydroxy-5Z,8Z,14Z-eicosatrienoic acid
Application: Bioactive lipid studies
MW: 338.5 D
From 159.00€ *
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(±)19(20)-DiHDPA
(±)19(20)-DiHDPA

Item number: Cay10007001-50

Docosahexaenoic acid (DHA, Cay-90310) is an essential fatty acid and the most abundant omega-3 fatty acid in neural tissues, especially in the retina and brain. (±)19(20)-DiHDPA is one of the major metabolites produced when DHA is incubated with NADPH-supplemented rat liver microsomes. DHA is also slowly metabolized...
Keywords: (±)19,20-DiHDoPE, (±)19,20-dihydroxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid
Application: Bioactive lipid assays
MW: 362.5 D
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Resolvin D5
Resolvin D5

Item number: Cay10007280-10

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D5 (RvD5) is a DHA-derived...
Keywords: 7(S),17(S)-diHDHA, 7(S),17(S)-Resolvin D5, RvD5, 7S,17S-dihydroxy-4Z,8E,10Z,13Z,15E,19Z-docosahexaenoic acid
Application: Lipid mediator
CAS 578008-43-2
MW: 360.5 D
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9(S)-HODE
9(S)-HODE

Item number: Cay38410-100

9(S)-HODE is a metabolite of the omega-6 polyunsaturated fatty acid linoleic acid (Cay-90150, Cay-90150.1, Cay-21909). It is formed from linoleic acid by lipoxygenases. 9(S)-HODE (68 µM) increases transactivation of peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma in reporter assays using...
Keywords: 9S-hydroxy-10E,12Z-octadecadienoic acid
Application: Bioactive lipid studies
CAS 73543-67-6
MW: 296.5 D
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Filipin III
Filipin III

Item number: Cay70440-1

Filipin III is a polyene and an active component of the polyene antibiotic filipin complex (Cay-25073). It is active against various fungi, including B. dermatitidis, C. neoformans, H. capsulatum, C. albicans, and T. mentagrophytes (MICs = 1-10 µg/ml). Filipin III induces hemolysis of isolated rabbit erythrocytes...
Keywords: 4S,6S,8S,10R,12R,14R,16S,27S-octahydroxy-3R-(1R-hydroxy-hexyl)17,28R-dimethyl-oxacyclooctacosa-17E,19E,21E,21E,23E,25E-pen...
Application: Bioactive lipid assays
CAS 480-49-9
MW: 654.8 D
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Eicosapentaenoic Acid-d5
Eicosapentaenoic Acid-d5

Item number: Cay10005056-50

Eicosapentaenoic acid-d5 (EPA-d5) is intended for use as an internal standard for the quantification of EPA (Cay-90110, Cay-90110.1, Cay-26415) by GC- or LC-MS. EPA is an omega-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively,...
Keywords: EPA-d5, Timnodonic Acid-d5, 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic-19,19,20,20,20-d5 acid
Application: Bioactive lipid assays
CAS 1197205-73-4
MW: 307.5 D
From 97.00€ *
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15 from 345 pages