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Item number: Cay90270-1
17-Octadecynoic Acid (17-ODYA) is a fatty acid alkyne. It is a suicide inhibitor of leukotriene B4 20-hydroxylase and renal CYP450 omega-hydroxylase. 17-ODYA (10 µM) completely inhibits the bradykinin-dependent transport of sodium chloride in rat TALH cells. It has been used as a click chemistry probe for labeling...
| Keywords: | 17-ODYA, Alk-16 |
| Application: | Bioactive lipid assays |
| CAS | 34450-18-5 |
| MW: | 280.5 D |
From 38.00€
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Item number: Cay10007534-5
Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant omega-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for...
| Keywords: | DEA, DHEA, Synaptamide, N-(2-hydroxyethyl)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenamide |
| Application: | Bioactive lipid assays |
| CAS | 162758-94-3 |
| MW: | 371.6 D |
From 53.00€
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Item number: Cay315210-25
6-keto Prostaglandin F1alpha-d4 (6-keto PGF1alpha-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 6-keto PGF1alpha (Cay-15210) by GC- or LC-MS. 6-keto PGF1alpha is the inactive, non-enzymatic hydrolysis product of PGI2....
| Keywords: | 6-keto PGF1alpha-d4, 6-oxo-9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic-3,3,4,4-d4 acid |
| Application: | Standard |
| CAS | 82414-64-0 |
| MW: | 374.5 D |
From 102.00€
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Item number: Cay10681-1
C16 Ceramide is a sphingolipid. It incorporates into the mitochondrial outer membrane and forms channels that increase its permeability. C16 Ceramide levels are increased by PPMP or MAPP in isolated human neutrophils and are correlated with an increase in apoptosis. It accumulates in the lungs of patients with...
| Keywords: | Cer(d18:1/16:0), Ceramide (d18:1/16:0), N-Palmitoyl-D-erythro-Sphingosine, Palmitoyl Ceramide,... |
| Application: | Bioactive lipid assays |
| CAS | 24696-26-2 |
| MW: | 537.9 D |
From 38.00€
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Item number: Cay316350-25
8-iso PGF2alpha-d4 is intended for use as an internal standard for the quantification of 8-iso PGF2alpha by GC- or LC-mass spectrometry. 8-iso Prostaglandin F2alpha (8-iso PGF2alpha) is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It circulates in human...
| Keywords: | 15-F2t-Isoprostane-d4, 8-epi PGF2alpha-d4, 8-Isoprostane-d4, iPF2alpha-III-d4,... |
| Application: | Standard |
| CAS | 211105-40-7 |
| MW: | 358.5 D |
From 295.00€
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Item number: Cay44230-25
5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. It is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs. 5(S)-HpETE (1 µM) mediates the induction of the proto-oncogene c-fos in TNF-stimulated TA1 cells.Formal Name:...
| Keywords: | 5S-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 71774-08-8 |
| MW: | 336.5 D |
From 159.00€
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Item number: Cay51511-25
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. (±)11(12)-DiHET relaxes U-46619 (Cay-16450)-contracted artery rings with approximately 70% of the magnitude of (±)11(12)-EET (Cay-50511).Formal Name: (±)11,12-dihydroxy-5Z,8Z,14Z-eicosatrienoic...
| Keywords: | (±)11,12-DiHETrE, (±)11,12-dihydroxy-5Z,8Z,14Z-eicosatrienoic acid |
| Application: | Bioactive lipid studies |
| MW: | 338.5 D |
From 159.00€
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Item number: Cay10007001-50
Docosahexaenoic acid (DHA, Cay-90310) is an essential fatty acid and the most abundant omega-3 fatty acid in neural tissues, especially in the retina and brain. (±)19(20)-DiHDPA is one of the major metabolites produced when DHA is incubated with NADPH-supplemented rat liver microsomes. DHA is also slowly metabolized...
| Keywords: | (±)19,20-DiHDoPE, (±)19,20-dihydroxy-4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid |
| Application: | Bioactive lipid assays |
| MW: | 362.5 D |
From 127.00€
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Item number: Cay10007280-10
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D5 (RvD5) is a DHA-derived...
| Keywords: | 7(S),17(S)-diHDHA, 7(S),17(S)-Resolvin D5, RvD5, 7S,17S-dihydroxy-4Z,8E,10Z,13Z,15E,19Z-docosahexaenoic acid |
| Application: | Lipid mediator |
| CAS | 578008-43-2 |
| MW: | 360.5 D |
From 228.00€
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Item number: Cay38410-100
9(S)-HODE is a metabolite of the omega-6 polyunsaturated fatty acid linoleic acid (Cay-90150, Cay-90150.1, Cay-21909). It is formed from linoleic acid by lipoxygenases. 9(S)-HODE (68 µM) increases transactivation of peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma in reporter assays using...
| Keywords: | 9S-hydroxy-10E,12Z-octadecadienoic acid |
| Application: | Bioactive lipid studies |
| CAS | 73543-67-6 |
| MW: | 296.5 D |
From 174.00€
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Item number: Cay70440-1
Filipin III is a polyene and an active component of the polyene antibiotic filipin complex (Cay-25073). It is active against various fungi, including B. dermatitidis, C. neoformans, H. capsulatum, C. albicans, and T. mentagrophytes (MICs = 1-10 µg/ml). Filipin III induces hemolysis of isolated rabbit erythrocytes...
| Keywords: | 4S,6S,8S,10R,12R,14R,16S,27S-octahydroxy-3R-(1R-hydroxy-hexyl)17,28R-dimethyl-oxacyclooctacosa-17E,19E,21E,21E,23E,25E-pen... |
| Application: | Bioactive lipid assays |
| CAS | 480-49-9 |
| MW: | 654.8 D |
From 177.00€
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Item number: Cay10005056-50
Eicosapentaenoic acid-d5 (EPA-d5) is intended for use as an internal standard for the quantification of EPA (Cay-90110, Cay-90110.1, Cay-26415) by GC- or LC-MS. EPA is an omega-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively,...
| Keywords: | EPA-d5, Timnodonic Acid-d5, 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic-19,19,20,20,20-d5 acid |
| Application: | Bioactive lipid assays |
| CAS | 1197205-73-4 |
| MW: | 307.5 D |
From 97.00€
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