No results were found for the filter!
8-iso Prostaglandin E1
Item number: Cay13360-10
Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 µg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2alpha.Formal Name:...
| Keywords: | 8-epi PGE1, 8-iso PGE1, Ovinonic acid, 9-oxo-11alpha,15S-dihydroxy-(8beta)-prost-13E-en-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 21003-46-3 |
| MW: | 354.5 D |
From 70.00€
*
tetranor-PGEM
Item number: Cay14840-25
tetranor-Prostaglandin E metabolite (tetranor-PGEM) is the major urinary metabolite of PGE2 (Cay-14010). Urine levels of tetranor-PGEM are increased in patients with diabetic nephropathy. Increased urine levels are also associated with a higher risk of breast cancer in postmenopausal women with a body mass index...
| Keywords: | tetranor-Prostaglandin E Metabolite, 9,15-dioxo-11alpha-hydroxy-13,14-dihydro-2,3,4,5-tetranor-prostan-1,20-dioic acid |
| Application: | Bioactive lipid assays |
| CAS | 24769-56-0 |
| MW: | 328.4 D |
From 182.00€
*
17-Octadecynoic Acid
Item number: Cay90270-1
17-Octadecynoic Acid (17-ODYA) is a fatty acid alkyne. It is a suicide inhibitor of leukotriene B4 20-hydroxylase and renal CYP450 omega-hydroxylase. 17-ODYA (10 µM) completely inhibits the bradykinin-dependent transport of sodium chloride in rat TALH cells. It has been used as a click chemistry probe for labeling...
| Keywords: | 17-ODYA, Alk-16 |
| Application: | Bioactive lipid assays |
| CAS | 34450-18-5 |
| MW: | 280.5 D |
From 23.00€
*
Docosahexaenoic Acid-d5
Item number: Cay10005057-50
Docosahexaenoic acid-d5 (DHA-d5) is intended for use as an internal standard for the quantification of DHA (Cay-90310) by GC- or LC-MS. DHA is a long-chain omega-3 polyunsaturated fatty acid (PUFA) found in fish and algal oils. It comprises approximately 40% of total brain PUFAs and is abundant in grey matter and...
| Keywords: | Cervonic Acid-d5, DHA-d5, 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic-21,21,22,22,22-d5 acid |
| Application: | Standard |
| CAS | 1197205-71-2 |
| MW: | 333.5 D |
From 94.00€
*
Docosahexaenoyl Ethanolamide
Item number: Cay10007534-5
Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant omega-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for...
| Keywords: | DEA, DHEA, Synaptamide, N-(2-hydroxyethyl)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenamide |
| Application: | Bioactive lipid assays |
| CAS | 162758-94-3 |
| MW: | 371.6 D |
From 48.00€
*
Tauroursodeoxycholic Acid
Item number: Cay20277-500
Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid (Cay-15121). TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears. It demonstrates anti-apoptotic activity in rodent models of tauopathy, Huntington's...
| Keywords: | 3alpha,7beta-dihydroxy-5beta-cholanoyl Taurine, TUDCA, UR-906,... |
| Application: | Secondary bile acid taurine conjugate |
| CAS | 14605-22-2 |
| MW: | 499.7 D |
From 78.00€
*
13(S)-HODE
Item number: Cay38610-100
13(S)-HODE is produced by incubation of linoleic acid with plant and mammalian lipoxygenases. It has been shown to inhibit the adhesion of tumor cells to the endothelium at concentrations around 1 µM, and down regulates the expression of the IRGpIIb/IIIa receptor.Formal Name: 13S-hydroxy-9Z,11E-octadecadienoic acid....
| Keywords: | 13S-hydroxy-9Z,11E-octadecadienoic acid |
| Application: | Adhesion inhibitor |
| CAS | 29623-28-7 |
| MW: | 296.5 D |
From 82.00€
*
8-iso Prostaglandin F2alpha-d4
Item number: Cay316350-25
8-iso PGF2alpha-d4 is intended for use as an internal standard for the quantification of 8-iso PGF2alpha by GC- or LC-mass spectrometry. 8-iso Prostaglandin F2alpha (8-iso PGF2alpha) is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It circulates in human...
| Keywords: | 15-F2t-Isoprostane-d4, 8-epi PGF2alpha-d4, 8-Isoprostane-d4, iPF2alpha-III-d4,... |
| Application: | Standard |
| CAS | 211105-40-7 |
| MW: | 358.5 D |
From 226.00€
*
Iloprost
Item number: Cay18215-1
Iloprost is a second generation structural analog of prostacyclin (PGI) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the human recombinant IP and EP1 receptors with a Ki of 11 nM. Iloprost constricts the isolated...
| Keywords: | Ciloprost, 6,9alpha-methylene-11alpha,15S-dihydroxy-16-methyl-prosta-5E,13E-dien-18-yn-1-oic acid |
| Application: | PGI analog |
| CAS | 78919-13-8 |
| MW: | 360.5 D |
From 35.00€
*
5(S)-HpETE
Item number: Cay44230-25
5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. It is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs. 5(S)-HpETE (1 µM) mediates the induction of the proto-oncogene c-fos in TNF-stimulated TA1 cells.Formal Name:...
| Keywords: | 5S-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 71774-08-8 |
| MW: | 336.5 D |
From 146.00€
*
(±)11(12)-DiHET
Item number: Cay51511-25
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. (±)11(12)-DiHET relaxes U-46619 (Cay-16450)-contracted artery rings with approximately 70% of the magnitude of (±)11(12)-EET (Cay-50511).Formal Name: (±)11,12-dihydroxy-5Z,8Z,14Z-eicosatrienoic...
| Keywords: | (±)11,12-DiHETrE, (±)11,12-dihydroxy-5Z,8Z,14Z-eicosatrienoic acid |
| Application: | Bioactive lipid studies |
| MW: | 338.5 D |
From 133.00€
*
Arachidonic Acid (sodium salt)
Item number: Cay10006607-100
Polyunsaturated fatty acids (PUFAs) are essential nutrients that show distinct deficiency syndromes when not present in adequate amounts in the diet. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free...
| Keywords: | Sodium Arachidonate, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, monosodium salt |
| Application: | Bioactive lipid assays |
| CAS | 6610-25-9 |
| MW: | 326.5 D |
From 69.00€
*