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1-Arachidonoyl Glycerol
Item number: Cay62150-1
The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands. 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand. However, 2-AG is chemically unstable and undergoes rapid...
| Keywords: | 1-AG, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 1-glyceryl ester |
| Application: | CB1 receptor agonist |
| CAS | 35474-99-8 |
| MW: | 378.6 D |
From 35.00€
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Lipid-based Drug Delivery Tools
1,2-Dimyristoyl-sn-glycero-3-PE
Item number: Cay15090-250
Phosphatidylethanolamines (PEs) are phospholipids found in biological membranes, serving both structural and functional roles. Different types of PEs are commonly used in the generation of micelles, liposomes, and other types of artificial membranes. 1,2-Dimyristoyl-sn-glycero-3-PE (1,2-DMPE) is a phospholipid...
| Keywords: | 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine, DMPE, 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine |
| Application: | Phospholipid |
| CAS | 998-07-2 |
| MW: | 635.9 D |
From 69.00€
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Arachidonoyl Ethanolamide-d8
Item number: Cay390050-100
Arachidonoyl ethanolamide-d8 (AEA-8) contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of AEA by GC- or LC-mass spectrometry. AEA is the ethanolamine amide of arachidonic acid, first isolated from porcine brain. It is...
| Keywords: | AEA-d8, Anandamide-d8, N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide-5,6,8,9,11,12,14,15-d8 |
| Application: | Standard |
| CAS | 924894-98-4 |
| MW: | 355.6 D |
From 67.00€
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(±)5-HETE
Item number: Cay34210-25
(±)5-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. It contains equal amounts of 5(S)-HETE and 5(R)-HETE. (±)5-HETE induces the aggregation of isolated neutrophils with an IC50 value of 200 nM.Formal Name: (±)5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid....
| Keywords: | (±)5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid studies |
| CAS | 73307-52-5 |
| MW: | 320.5 D |
From 99.00€
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(±)12(13)-EpOME
Item number: Cay52450-250
(±)12(13)-EpOME is the 12,13-cis epoxide form of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909). It is formed primarily via linoleic acid metabolism by the cytochrome P450 (CYP) isoforms CYP2J2, CYP2C8, and CYP2C9, however, CYP1A1 can contribute to (±)12(13)-EpOME production when pharmacologically induced....
| Keywords: | (±)12,13-EODE, (±)-Vernolic Acid, Isoleukotoxin, (±)12(13)epoxy-9Z-octadecenoic acid |
| Application: | Bioactive lipid studies |
| MW: | 296.5 D |
From 53.00€
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Ganglioside GM1 . sodium salt (bovine brain)
Item number: AG-CN2-9000-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Keywords: | GM1 . Na, Monosialoganglioside GM1 . Na |
| Application: | Acidic glycosphingolipid |
| CAS | 37758-47-7 |
| MW: | 1545,8 D |
From 99.00€
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1,2,3-Triheptadecanoyl Glycerol
Item number: Cay16489-1
1,2,3-Triheptadecanoyl glycerol is a triacylglycerol that contains heptadecanoic acid (Cay-19722) at the sn-1, sn-2, and sn-3 positions.Formal Name: heptadecanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester. CAS Number: 2438-40-6. Synonyms: Glycerol Triheptadecanoate, TG(17:0/17:0/17:0). Molecular Formula: C54H104O6....
| Keywords: | Glycerol Triheptadecanoate, TG(17:0/17:0/17:0), heptadecanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester |
| Application: | Saturated triacylglycerol |
| CAS | 2438-40-6 |
| MW: | 849.4 D |
From 44.00€
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Prostaglandin J2
Item number: Cay18500-500
Prostaglandin J2 (PGJ2) is a metabolite of PGD2 (Cay-12010) and an agonist of the prostaglandin D2 (PGD2) receptor subtypes DP1 and DP2/CRTH. It is formed from PGD2 by spontaneous dehydration. PGJ2 binds to DP1 and DP2/CRTH receptors (Kis = 0.9 and 6.6 nM, respectively) and either increases or inhibits the...
| Keywords: | PGJ2, 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 60203-57-8 |
| MW: | 334.5 D |
From 121.00€
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DMPC (1,2-Dimyristoyl-sn-glycero-3-phosphocholine) (14:0 PC)
Item number: IAX-700-400-5050
1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid utilized in liposomes and lipid bilayers for the study of biological membranes. Its utility extends to investigating the influence of lipids on enzymatic activity and protein function when formulated into nanodiscs, LNP or liposomes....
| Keywords: | 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (14:0 PC) |
| Application: | Synthetic phospholipid |
| CAS | 18194-24-6 |
| MW: | 677,9 D |
From 74.00€
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Xestospongin C
Item number: Cay64950-10
Xestospongin C is a marine natural product which was first isolated from Pacific basin sponges, and noted to have vasodilatory properties. Xestospongin C antagonizes the calcium-releasing action of inositol-1,4,5-trisphosphate (IP3) at the receptor level. Inositol phosphates are important signal transduction...
| Keywords: | Araguspongine E, XeC,... |
| Application: | Bioactive lipid assays |
| CAS | 88903-69-9 |
| MW: | 446.7 D |
From 117.00€
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N-Arachidonoyl Dopamine
Item number: Cay90057-5
N-Arachidonoyl dopamine (NADA) is an arachidonoyl amino acid and cannabinoid (CB) receptor 1 agonist (Ki = 250 nM in rat brain membranes, which highly express CB1 receptors). It is selective for CB1 over CB2 receptors (Ki = 12,000 nM in rat spleen membranes, which highly express CB2 receptors). NADA induces...
| Keywords: | NADA, N-[2-(3,4-dihydroxyphenyl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide |
| Application: | CB1 agonist |
| CAS | 199875-69-9 |
| MW: | 439.6 D |
From 74.00€
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gamma-Linolenic Acid
Item number: Cay90220-50
gamma-Linolenic acid (GLA) is an omega-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM. GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model...
| Keywords: | GLA, 6Z,9Z,12Z-octadecatrienoic acid |
| Application: | LTB4 receptor antagonist |
| CAS | 506-26-3 |
| MW: | 278.4 D |
From 35.00€
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